Brain age gap reduction following exercise mirrors clinical improvements in schizophrenia spectrum disorders [0.03%]
运动干预可缩小精神分裂症谱系障碍患者的脑年龄差距并改善临床症状
Deniz Yilmaz,Sergi Papiol,Daniel Keeser et al.
Deniz Yilmaz et al.
Schizophrenia spectrum disorders (SSD) are associated with accelerated brain aging, reflected in an increased brain age gap. This gap serves as a biomarker, indicating poorer brain health, cognitive deficits, and greater severity in specifi...
OPM-MEG in multiple sclerosis: Proof of principle, and the effect of naturalistic posture [0.03%]
多发性硬化病的OPM-MEG检查：初步理论及自然体位的影响
Benjamin J Sanders,Christopher G S Gilmartin,Lukas Rier et al.
Benjamin J Sanders et al.
Multiple Sclerosis (MS) is a common neurological disorder in which myelin damage affects neuronal signalling. Magnetoencephalography (MEG - the measurement of magnetic fields generated by neuronal currents) offers metrics of brain function ...
Deep convolutional neural networks outperform vanilla machine learning when predicting language outcomes after stroke [0.03%]
深度卷积神经网络在预测卒中后语言预后方面优于常规机器学习
Thomas M H Hope,Howard Bowman,Alex P Leff et al.
Thomas M H Hope et al.
Background: Current medicine cannot confidently predict patients' language skills after stroke. In recent years, researchers have sought to bridge this gap with machine learning. These models appear to benefit from access...
The impact of prenatal alcohol and tobacco exposure on white matter integrity in 8-12-year-old children [0.03%]
孕期酒精和烟草暴露对8至12岁儿童大脑白质完整性的影响
Annerine Roos,Deborah Jonker,Eric Kan et al.
Annerine Roos et al.
The combined impact of prenatal alcohol exposure (PAE) and prenatal tobacco exposure (PTE) on white-matter integrity in pre-adolescence is poorly understood. We aimed to explore white-matter integrity in children aged 8- to 12-years with PA...
Comparison of thalamic atlases and segmentation techniques in defining motor and sensory nuclei for deep brain stimulation targeting in essential tremor [0.03%]
震颤性必要震颤的深脑刺激靶点定位中运动和感觉核团的丘脑 atlas 和分割方法比较
Mathew E Zilberman,Kelvin L Chou,Parag G Patil et al.
Mathew E Zilberman et al.
Introduction: Many thalamic atlases are available for deep brain stimulation (DBS) applications, but their usage and clinical validation vary. This study investigated the effectiveness of six atlases in DBS targeting for ...
Cortical tortuosity as a potential clinical biomarker for Alzheimer's disease: A 3D MRI analysis of brain morphological changes [0.03%]
皮层扭曲度作为阿尔茨海默病的临床生物标志物的潜力：一种关于大脑形态变化的三维磁共振成像分析方法
Maria-Julieta Mateos,James J Lah,Deqiang Qiu
Maria-Julieta Mateos
Background: Alzheimer's disease (AD) is characterized by progressive brain morphological changes that are not fully captured by traditional volumetric measures. Cortical tortuosity, a novel measure of cortical folding com...
Selective association of EEG microstates with clinical symptoms and mutation status in monogenic Alzheimer disease [0.03%]
单基因阿尔茨海默病中EEG微状态与临床症状和突变状态的选择性关联
Charlotte Johansson,Thomas Koenig,Una Smailovic et al.
Charlotte Johansson et al.
EEG microstates are transient and short-lasting periods of stable scalp potential fields that are associated with disturbed temporal dynamics of large-scale brain networks, affected by early synaptic loss in Alzheimer disease (AD). We inves...
Understanding the development of neural abnormalities in adolescents with mental health problems: A longitudinal study [0.03%]
纵向研究理解青少年心理健康问题引起的神经异常发展
Jiangyun Hou,Laurens van de Mortel,Weijian Liu et al.
Jiangyun Hou et al.
Background: Many mental health problems are neurodevelopmental in nature and have an onset during childhood. These disorders are associated with neural abnormalities, but it is unclear when these emerge and how this relat...
Brain white matter microstructure associations with blood markers of the GSH redox cycle in schizophrenia [0.03%]
精神分裂症患者大脑髓鞘结构与谷胱甘肽氧化还原循环血液标志物之间的关系
Tommaso Pavan,Pascal Steullet,Yasser Alemán-Gómez et al.
Tommaso Pavan et al.
In groups of patients suffering from schizophrenia (SZ), redox dysregulation was reported in both peripheral fluids and brain. It has been hypothesized that such dysregulation, including alterations of the glutathione (GSH) cycle could part...
Association of quantitative susceptibility mapping signal in gray matter with clinical characteristics and aging-related MRI markers: The Multi-Ethnic Study of Atherosclerosis [0.03%]
基于多族裔动脉粥样硬化研究的灰质定量磁敏感信号与临床特征和衰老相关MRI标志物的关系研究
Susan R Heckbert,Paul N Jensen,Tanweer Rashid et al.
Susan R Heckbert et al.
Background and objectives: In neuropathologic studies, iron accumulation in gray matter (GM) is associated with aging and specific neurological diseases, but less is known about its correlates in community-based populatio...