Validation of deep-learning-based MRI-to-CT attenuation correction for striatal and extrastriatal [123I]I-FP-CIT SPECT measurement [0.03%]
基于深度学习的MRI至CT衰减校正验证在纹状体和非纹状体中进行[123I]FP-CIT SPECT测量中的应用
Sebastian Kalytta,Hendrik Theis,Kathrin Giehl et al.
Sebastian Kalytta et al.
Purpose: Attenuation correction is critical for accurate SPECT brain imaging and to quantify uptake ratios in neurological and psychiatric disorders. This prospective study aimed to validate the use of deep-learning-based...
Age-dependent alterations in anterior cingulate excitation-inhibition balance in major depressive disorder revealed by 7-Tesla magnetic resonance spectroscopy [0.03%]
利用7-特斯拉磁共振光谱术探讨抑郁症患者前扣带回兴奋/抑制平衡的年龄相关变化
Yujiro Yoshihara,Taro Suwa,Manabu Kubota et al.
Yujiro Yoshihara et al.
Background: Altered excitation-inhibition (E/I) balance has been implicated in the pathophysiology of major depressive disorder (MDD), but previous magnetic resonance spectroscopy (MRS) findings have been inconsistent, pa...
Fronto-striatal neurometabolite signatures of impulsivity in early abstinence from methamphetamine [0.03%]
冰毒戒断早期冲动行为的额底代谢物标志物谱型研究
Alexandru M Dumitrescu,M Frances Vest,Jennifer M Loftis et al.
Alexandru M Dumitrescu et al.
Background: Methamphetamine use is associated with neurometabolite alterations and increased impulsivity, but relationships between neurometabolites and specific impulsivity dimensions remain unclear, particularly during ...
Cerebellar structure is abnormal in schizophrenia and deviates from bipolar disorder [0.03%]
小脑结构在精神分裂症中异常并偏离双相情感障碍
Mahmoud Rashidi,Jayden Morales,Zachary Brodnick et al.
Mahmoud Rashidi et al.
The cerebellum has been implicated in schizophrenia-related structural and functional deficits, with posterior Crus I and II most consistently affected. Source-based morphometry (SBM) involves applying independent component analysis to gray...
A comparative study of deep learning for cortical lesion MRI segmentation with explainability analysis in multiple sclerosis [0.03%]
一种用于多发性硬化症皮质病变MRI分割的深度学习比较研究及其可解释性分析
Nataliia Molchanova,Alessandro Cagol,Mario Ocampo-Pineda et al.
Nataliia Molchanova et al.
Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic resonan...
A spectral- topological network signature of drug-resistant epilepsy: a phase 1-2 study on resting-state EEG-based diagnostic biomarkers of drug resistance [0.03%]
基于静息态EEG的难治性癫痫诊断生物标志物Ⅰ-Ⅱ期研究：一种谱-拓扑网络特征.signature-of-drug-resistant-epilepsy-a-phase-1-2-study-on-resting-state-eeg-based-diagnostic-biomarkers-of-drug-resistance
B M Sancetta,J Lanzone,M A G Matarrese et al.
B M Sancetta et al.
Objective: Drug-resistant epilepsy (DRE) is increasingly recognized as a disorder of large-scale brain networks. Here, we evaluated a candidate resting-state EEG-based biomarker for identifying DRE in a diagnostic context...
Age-related changes to brain energetics revealed by PET/MRI imaging [0.03%]
PET/MRI成像揭示与年龄相关的脑能量代谢变化
Connor W J Bevington,Sahib Dhaliwal,Jessamyn McKenzie et al.
Connor W J Bevington et al.
Aging is accompanied by several neurophysiological changes. Of recent interest are age-related changes in brain energetics-how the brain produces and uses energy. In vitro, preclinical, and genetic investigations point to a general decline ...
Structural-functional multilayer brain network properties and outcome of combined repetitive transcranial magnetic stimulation and psychotherapy for obsessive-compulsive disorder [0.03%]
经颅磁刺激联合心理治疗对强迫症患者预后的结构功能多层脑网络属性的影响研究
Sophie M D D Fitzsimmons,Coen Coomans,Lucas Breedt et al.
Sophie M D D Fitzsimmons et al.
Background: Repetitive transcranial magnetic stimulation (rTMS) is a promising treatment for obsessive-compulsive disorder (OCD), but response rates are variable. Pre-treatment characteristics of the stimulated region can...
Effects of antidepressant medications on brain tissue microstructure in persistent depressive disorder across two randomized controlled trials [0.03%]
两类抗抑郁药物对难治性抑郁症患者脑白质微观结构影响的随机对照研究
Ravi Bansal,David J Hellerstein,Siddhant Sawardekar et al.
Ravi Bansal et al.
Background: Prior studies have reported abnormalities in brain volumes and white matter microarchitecture in persistent depressive disorder(PDD). Randomized controlled trials(RCTs) yoked with brain MRIs are needed to disc...
Large scale functional and effective connectivity alterations cross the Huntington's disease integrated staging system [0.03%]
亨廷顿病整合分期系统的连接性改变
Murat Demirtas,Dorian Pustina,Andrew Wood et al.
Murat Demirtas et al.
Huntington's disease (HD) is a progressive neurodegenerative disease with severe motor, cognitive and behavioral symptoms. There is a recent impetus to develop treatments that slow progression before clinical signs emerge. Such early interv...