Krueppel-like factors transcriptionally regulate idiopathic pulmonary fibrosis [0.03%]
Krüppelin样因子转录调节特发性肺纤维化
Aritra Bhattacharyya,Alak Kumar Shyamal
Aritra Bhattacharyya
Idiopathic pulmonary fibrosis (IPF) is a devastating interstitial lung disease (ILD) characterized by excessive inflammation and deposition of extracellular matrix (ECM) in the pulmonary niche, ultimately leading to decline of pulmonary fun...
Early rehabilitation after acute exacerbation of idiopathic pulmonary fibrosis: A nationwide observational study [0.03%]
特发性肺纤维化急性加重后的早期康复：一项全国性的观察研究
Nobuyasu Awano,Shotaro Aso,Takehiro Izumo et al.
Nobuyasu Awano et al.
Background: Despite strong recommendations for pulmonary rehabilitation in stable idiopathic pulmonary fibrosis, its efficacy during acute exacerbation (AE-IPF) remains unclear. This study aimed to investigate the effect ...
Inhaled granulocyte-macrophage colony-stimulating for autoimmune pulmonary alveolar proteinosis: From pathogenesis to clinical practice [0.03%]
吸入性粒细胞-巨噬细胞集落刺激因子治疗自身免疫性肺泡蛋白沉积症：从发病机制到临床实践
Ryushi Tazawa
Ryushi Tazawa
Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare, diffuse lung disease characterized by surfactant accumulation in the alveoli, leading to impaired gas exchange and progressive respiratory insufficiency. It is caused by neutralizi...
Association between fentanyl dose and willingness to undergo repeat bronchoscopy in a standardized EBUS-GS-TBB setting [0.03%]
不同剂量芬太尼对超声支气管镜经支气管针吸活检镇痛效果的影响
Kazuya Monden,Ayumi Akamatsu,Yohei Takada et al.
Kazuya Monden et al.
Background: Discomfort experienced during bronchoscopy may limit patients' willingness to undergo repeat procedures. Although guidelines recommend benzodiazepine-opioid sedation, evidence regarding optimal opioid dosing r...
Systemic artery-to-pulmonary artery fistula and ectopic pancreas successfully treated for hemoptysis by transarterial embolization and subsequent surgical resection: a case report [0.03%]
支气管动脉-肺动脉瘘及支气管异位胰腺导致咯血的血管介入栓塞治疗和外科手术切除1例报告
Rie Watanabe,Keiko Tanimura,Ryo Kimura et al.
Rie Watanabe et al.
A 79-year-old woman presented with progressive hemoptysis. Computed tomography revealed a systemic artery-to-pulmonary artery fistula (SA-PAF) extending from the left upper lobe to the anterior mediastinum. The SA-PAF was treated with trans...
The JRS guideline for the management of chronic obstructive pulmonary disease 7th edition 2026 [0.03%]
日本呼吸器学会慢性阻塞性肺疾患管理ガイドライン第七版(2026)
Hisatoshi Sugiura,Naoya Fujino,Yoko Shibata et al.
Hisatoshi Sugiura et al.
Chronic obstructive pulmonary disease (COPD) remains a major cause of morbidity and mortality in Japan, with an estimated prevalence of 8.6% among adults over 40 years of age, yet fewer than 10% of affected individuals receive a formal diag...
Prevalence and functional impact of respiratory sarcopenia in a COPD-enriched smoking cohort [0.03%]
吸烟伴COPD高风险受试者中呼吸肌群萎缩的流行病学特征及其临床影响研究
Yuji Yoshioka,Naoya Tanabe,Yohei Oshima et al.
Yuji Yoshioka et al.
Background: Respiratory sarcopenia, defined as a combination of respiratory muscle weakness and decreased respiratory muscle mass, is a novel concept with unclear prevalence and clinical relevance in the chronic obstructi...
Revisiting nursing- and healthcare-associated pneumonia in Japan: Microbiology, multidrug resistance, and clinical outcomes compared with community-acquired pneumonia [0.03%]
日本医疗保健相关性肺炎的再评价：微生物学、多药耐药和临床结局与社区获得性肺炎的比较
Yusuke Tomita,Hiroshi Moro,Nobumasa Aoki et al.
Yusuke Tomita et al.
Background: In Japan, nursing- and healthcare-associated pneumonia (NHCAP) is used to describe pneumonia in patients with substantial exposure to healthcare and nursing care services. A systematic review and meta-analysis...
Investigation of factors affecting the accuracy of portable monitors in Japanese professional drivers with suspected obstructive sleep apnea [0.03%]
日本职业司机阻塞性睡眠呼吸暂停可疑情况下影响便携式监测准确性的因素调查研究
Masako Ueyama,Hiroyuki Kokuto,Shoji Kudoh et al.
Masako Ueyama et al.
Background: Portable monitors (PMs) are widely used for obstructive sleep apnea (OSA) screening in Japan. Appropriate interpretation of PM results and decisions regarding subsequent polysomnography (PSG) are essential to ...
Donor selection in living-donor lung transplantation for familial pulmonary fibrosis: A narrative review and single-center practical approach [0.03%]
家族性肺纤维化活体供体肺移植的供者选择：叙事综述及单中心实践方法
Tomohiro Handa,Toyofumi Fengshi Chen-Yoshikawa,Hidenori Kawasaki et al.
Tomohiro Handa et al.
In Japan, living-donor lobar lung transplantation (LDLLT) remains an important therapeutic option because of the persistent shortage of brain-dead donors. Interstitial lung diseases (ILDs) are a major indication for transplantation; however...