The effect of pharmacotherapy for attention deficit hyperactivity disorder on risk of seizures in pediatric patients as assessed in an insurance claims database [0.03%]
一项基于保险理赔数据库的注意缺陷多动障碍儿童患者的药物治疗对癫痫风险影响的研究
Andrew T McAfee,Karen C Holdridge,Catherine B Johannes et al.
Andrew T McAfee et al.
Purpose: To estimate the rate of new-onset seizure in ADHD patients in relation to ADHD pharmacotherapy. Methods: A retrospective cohor...
Robert J Flanagan
Robert J Flanagan
The recognition, management, and if possible prevention, of major cardiovascular, central nervous system, haematological, and metabolic adverse effects, including diabetes mellitus and weight gain, of antipsychotics and some other drugs use...
Advances in machine learning prediction of toxicological properties and adverse drug reactions of pharmaceutical agents [0.03%]
药物机器学习预测毒理学性质及不良反应的新进展
Xiao Hua Ma,Rong Wang,Yin Xue et al.
Xiao Hua Ma et al.
As part of the intensive efforts in facilitating drug discovery, computational methods have been explored as low-cost and efficient tools for predicting various toxicological properties and adverse drug reactions (ADR) of pharmaceutical age...
Immune monitoring to predict the development of infections after immunosuppression for solid organ transplantation and autoimmune diseases [0.03%]
免疫监测在实体器官移植和自身免疫性疾病免疫抑制后感染发生风险中的预测作用
Javier Carbone,Nallibe Lanio,Antonio Gallego et al.
Javier Carbone et al.
Infections are relevant complications that cause morbidity in solid organ transplantation and autoimmune diseases. Infection represents a leading single cause of death in these patients. Identification of patients at risk for development of...
Demissie Alemayehu
Demissie Alemayehu
We consider the management of safety signals that arise in the context of endpoint trials. Such trials have design features which permit the detection of signals that otherwise may be missed in more traditional settings. However, the approa...