Adverse Drug Reaction Profile of Capecitabine-based Chemotherapy Regimen and its Predisposing Factors in Patients Attending a Tertiary Care Hospital in South India [0.03%]
卡培他滨化疗方案不良反应的临床特征及其影响因素分析——南印度一家三级医院的回顾性研究
Avishek Amar,Jayanthi Mathaiyan,Biswajit Dubashi
Avishek Amar
Background: Capecitabine, an important drug used for solid tumors involving the gastrointestinal tract, is known to be associated with many Adverse Drug Reactions (ADRs) leading to dose modification or discontinuation. ...
The Impact of Non-Steroidal Anti-Inflammatory Drugs on Gastrointestinal Bleeding: Review on Risk Scoring for Better Prediction [0.03%]
非甾体抗炎药导致胃肠出血的影响：综述评分以更好预测风险
Dwi Aris Agung Nugrahaningsih,- Mustofa,Woro Rukmi Pratiwi et al.
Dwi Aris Agung Nugrahaningsih et al.
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed for pain relief and inflammation management; however, they can lead to serious upper gastrointestinal (GI) issues, including ulcers, bleeding, and perforations. This rev...
DRESS Syndrome with Cold Agglutinins: An Unusual Immune Response to Anticonvulsants [0.03%]
药物致敏引起的冷凝集素病并DRESS综合征
Sumit Jaiswal,Sourabh Pathania,Gaurav Sharma et al.
Sumit Jaiswal et al.
Introduction: DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) is a rare adverse drug reaction characterized by cutaneous and systemic manifestations, with a mortality rate of up to 10%. In this study, we des...
Evaluating the Impact of SGLT-2 Inhibitors on Frailty in Older Adults: A Clinical Review [0.03%]
钠-葡萄糖协同转运蛋白-2抑制剂对老年人脆弱性影响的临床评价
Sulthan Al Rashid,Abinaya Vannapatti Gopalakrishnan,Naina Mohamed Pakkir Maideen et al.
Sulthan Al Rashid et al.
Background: Sodium-glucose cotransporter-2 (SGLT-2) inhibitors, including empagliflozin, canagliflozin, and dapagliflozin, have demonstrated significant cardiovascular and renal benefits in managing type 2 diabetes mellit...
Simran Kaur,Simran Yadav,Vishesh Sahu et al.
Simran Kaur et al.
Introduction/objective: Biosimilars, a class of biologic medications that are highly similar to reference biologics, have emerged as cost-effective alternatives to their expensive originator counterparts. Due to their com...
Afifa Akram,Radhakrishan Gaur,Indu SIngh et al.
Afifa Akram et al.
Objective: This review investigates the regulatory framework for dermocosmetic bioactive in functional skincare, focusing on products with both cosmetic and pharmaceutical characteristics. The global regulatory environmen...
A Review on Process Analytical Technology as a Driver of Pharmaceutical Manufacturing for the Improvement of Quality while Reducing Costs [0.03%]
从改善质量及降低成本的角度探讨过程分析技术对药品制造的推动作用的综述
Ritwik Adak,Arinya Jana,Biplab Debnath et al.
Ritwik Adak et al.
Process analytical technology has emerged as a possible game-changing platform in the pharmaceutical business to improve process knowledge while also improving product quality and lowering production costs. This paper outlines the underlyin...
Identification and Detection of Pharmaceutical Impurities for Ensuring Safety Standard of Medicine: Hyphenated Analytical Techniques and Toxicity Measurements [0.03%]
药物安全标准中的杂质识别与检测：联用技术及其毒性测量
S K Azizuddin,Asif Husain,Mohammad Rashid et al.
S K Azizuddin et al.
Impurity separation and detection are essential processes in the pharmaceutical industry to preserve the quality of drugs as the impurities have the potential to significantly impair the therapeutic efficacy of an active ingredient and have...
Safety Profile of Amantadine: A Comprehensive Analysis of Real-World Adverse Events from the FDA Adverse Event Reporting System Database [0.03%]
金刚烷胺的安全性评估：来自美国食品药品监督管理局不良事件通报系统数据库的meta分析
Wenpei Chen,Xianjun Chen
Wenpei Chen
Background: Traumatic Brain Injury (TBI) is a significant public health issue, often leading to long-term cognitive, physical, and emotional impairments. Amantadine has emerged as a treatment option due to its potential n...
Optimizing Antibiotic use and Awareness in Hospitals: Establishing Effective Antimicrobial Stewardship Pathways [0.03%]
医院抗菌药物优化使用与管理认知：建立有效的抗菌药物管理工作路径
Bianca Maria Donida,Grazia Mingolla,Antonio Manfredi
Bianca Maria Donida
Background: Antibiotic resistance poses a significant challenge in healthcare, requiring effective management of antibiotic use. This study examines systemic antibiotic consumption at ASST Bergamo Ovest, a northern Italia...