Advancements in Colon Cancer Therapy: A Review on Docetaxel and the Role of Nanotechnology in Enhancing Efficacy [0.03%]
结肠癌治疗的进展：关于多西他赛的综述及纳米技术在提高疗效中的作用
Komal,Dinesh Kumar,Sharib Raza Khan et al.
Komal et al.
Docetaxel exhibits high protein binding and P450-mediated metabolism, which influences its pharmacokinetics. As a taxane-family chemotherapeutic agent, it stabilizes microtubules and disrupts cell division. Combining docetaxel with agents l...
Ajita Kapur,Munish Sharma,Kapil Hazarika
Ajita Kapur
Introduction: Acute parotid gland enlargement is an extremely rare post-surgical complication. Several etiological factors have been proposed, including preoperative dehydration, medications that cause an increase in visc...
Pharmacovigilance - Technological Advancements, Recent Developments and Innovations [0.03%]
药物警戒技术进展及创新举措
Virendra S Gomase
Virendra S Gomase
Pharmacovigilance is an important subject in medicine and healthcare, which aims to prevent side effects and other drug-related problems by identifying, evaluating, understanding, and avoiding them. Its main objectives are ensuring that a d...
Transdermal Drug Delivery Systems: Integrating Modern Technology for Enhanced Therapeutics [0.03%]
经皮药物输送系统：整合现代技术以增强治疗效果
Tanvi Kathuria,Renu Saharan,Sanchit Dhankhar et al.
Tanvi Kathuria et al.
Background: In recent years, transdermal drug delivery systems (TDDS) have gained popularity as a non-invasive, patient-friendly medication delivery method. ...
Extreme and Severe Systemic Pain Caused by Rifampicin: A Case Report of a Rare Allergic Reaction [0.03%]
由利福平引起的严重全身疼痛性过敏反应：一例罕见病例报告
Tong-Xin Li,Yan-Mei Xiong,Wen-Wan Gao et al.
Tong-Xin Li et al.
Background: Rifampicin is a first-line anti-tuberculosis drug, but it may cause severe allergic adverse reactions. Case presentation: T...
Comprehensive Review of Gestational Diabetes: Pathophysiology, Pharmacological Management and the Role of Pharmaceutical Care [0.03%]
妊娠期糖尿病综述：病理生理、药理管理及药物治疗的作用
Abdulkadir Abdu,Hossamaldeen Bakrey
Abdulkadir Abdu
This review addresses the significant part pharmacological treatment plays in treating gestational diabetes mellitus (GDM), therefore enhancing the results for mother and child. Talking about the frequency and relevance of GDM would help to...
Rhabdomyolysis Following Trimethoprim-Sulfamethoxazole Therapy: A Case Report and Review of the Literature [0.03%]
复方新诺明治疗后发生横纹肌溶解症一例及文献复习
Mahjoubi Yasmine Salem,Zgolli Fatma,Dahmani Israa et al.
Mahjoubi Yasmine Salem et al.
Background: Trimethoprim-Sulfamethoxazole (TMP-SMX) is a commonly used antibiotic for the treatment of several infections, such as urinary tract infections, respiratory infections, and in certain cases, septic arthritis. ...
Reported Postoperative Surgical Site Infections in Tertiary Care Hospitals, Systematic Review of Recent Literature [0.03%]
三级医院术后手术部位感染的报告:近期文献综述
Soam Nadeem,Afra Abdul Hameed,Syed Wasif Gillani et al.
Soam Nadeem et al.
Purpose: The objective of this systematic review is to evaluate the patterns of postsurgical site infections, pre-surgical antibiotics prophylaxis, and related clinical outcomes in the recently published literature. ...
Priya Mehta,Pooja Sapovadia,Bhargav Purohit
Priya Mehta
Background: Clomipramine, a Tricyclic Antidepressant (TCA), is known for its efficacy in treating Obsessive-compulsive Disorder (OCD). However, it is associated with several side effects, including urinary retention. This...
Efficacy and Safety of Adding 1μg/Kg Dexmedetomidine to 20ml Bupivacaine in Supraclavicular Brachial Plexus Block: A Randomized Trial [0.03%]
右美托咪定添加至布比卡因为 supraclavicular brachial plexus block 的有效性和安全性：一项随机试验
Basma M Ghoniem,Gamal Hendawy Shams,Wafaa Abdelsalam et al.
Basma M Ghoniem et al.
Background: For surgical procedures of the upper limbs, ultrasound-guided supraclavicular brachial plexus block (SCBPB) represents a safe substitute for general anesthesia. The present study evaluated the effectiveness an...
Clinical Trial
Current drug safety. 2025 Jan 13. DOI:10.2174/0115748863332349241108094956 2025