Guillermo Alberto Keller,Guillermo Di Girolamo
Guillermo Alberto Keller
Antihistamines are drugs frequently used. Several drugs in this family had to be withdrawn from the market or limited in their marketing due to potentially fatal adverse events. These events were related to the ability of some antihistamine...
QT interval prolongation: preclinical and clinical testing arrhythmogenesis in drugs and regulatory implications [0.03%]
药物诱发的QT间期延长导致心律失常的研究及药政管理问题
Mariano A Giorgi,Ricardo Bolaños,Claudio Daniel Gonzalez et al.
Mariano A Giorgi et al.
The assessment about the proarrhythmic risk associated with a particular drug is a major requirement for drugs under development, since many drugs have been withdrawn from market or got under strict pharmacological vigilance because of such...
Marcelo Luis Ponte,Guillermo Alberto Keller,Guillermo Di Girolamo
Marcelo Luis Ponte
The long QT syndrome (LQTS) is characterized by a prolonged QT interval, as well as a propensity to develop syncope and sudden cardiac death caused by the malignant polymorphic ventricular arrhythmia called torsades de pointes (TdP). The QT...
Sarah Peterson,Yimin Chen
Sarah Peterson
The nutrition support clinician must understand and evaluate all aspects of parenteral nutrition (PN) to maximize benefits while avoiding unfavorable consequences for the patients in the intensive care unit. The various aspects in caring fo...
Nicole Pitello,Michelle Treon,Kellie L Jones et al.
Nicole Pitello et al.
Guidelines on how to treat cancer patients receiving cytotoxic chemotherapy in the intensive care unit (ICU) are very limited. Recognizing the severity of the patient, their disease may require the need for chemotherapy whether for localize...
Mira Loh-Trivedi,W Christopher Croley
Mira Loh-Trivedi
Critically ill patients admitted to intensive care units (ICUs) often present with multiple medical or surgical problems requiring a high level of care. In addition to a patient's underlying illness, a number of known risk factors can predi...
Allison Forni,Hanh T Chu,John Fanikos
Allison Forni
Medication errors have been increasingly recognized as a major cause of iatrogenic illness and system-wide improvements have been the focus of prevention efforts. Critically ill patients are particularly vulnerable to injury resulting from ...
Optimizing sustained use of sedation in mechanically ventilated patients: focus on safety [0.03%]
机械通气患者的镇静治疗：重视安全性
Heather M Arnold,James M Hollands,Lee P Skrupky et al.
Heather M Arnold et al.
Optimizing sustained use of ICU sedation in mechanically ventilated patients requires careful consideration of drug-specific characteristics (E.G. pharmacokinetics), consideration of potential adverse effects in susceptible patients, and ut...
G Patel Patel,Sandra L Kane-Gill
G Patel Patel
Medication errors are a common unfortunate occurrence in hospitals. One population that is particularly vulnerable are patients admitted to the Intensive Care Unit (ICU). ICU patients have a combination of rapidly changing medical condition...
Retraction Notice: Clinical Management of Postoperative Vomiting after Strabismus Surgery in Children [0.03%]
撤稿：儿童斜视手术后呕吐的临床处理
Yoshitaka Fujii
Yoshitaka Fujii
Formal retraction notice of article entitled Clinical Management of Postoperative Vomiting after Strabismus Surgery in Children (Curr Drug Saf. 2010 Apr; 5(2):132-48) by Dr Y. Fujii. This article is being retracted as a result of: Failure o...