Pharmacovigilance in Geriatrics: Exploration of Etio-Clinical Profile and Severity of Adverse Drug Reactions at a Tertiary Hospital in South India [0.03%]
老年病学中的药物警戒：在印度南部一家三级医院探索不良药物反应的病因临床特征及严重性
Jerin James,Gowtham B,Kala P et al.
Jerin James et al.
Background: The increasing geriatric population worldwide necessitates focused attention on medication management due to altered physiological and pharmacokinetic profiles. This study aims to explore the etio-clinical pro...
Linezolid Related Adverse Effects in Different Populations: A Practical Review [0.03%]
不同人群中与利奈唑胺相关的不良反应：实用综述
Foroud Shahbazi
Foroud Shahbazi
Linezolid, an oxazolidinone antibiotic, is used to treat gram-positive infections. However, it may also lead to serious adverse effects, including bone marrow suppression, optic neuropathy, peripheral neuropathy, hyponatremia, and lactic ac...
Self-Micro-Emulsifying Drug Delivery Systems: In-Depth Review on Enhancing Solubility and Therapeutic Efficacy of BCS Class II Drugs [0.03%]
自微乳化递药系统：提高BCS II类药物溶解性和治疗效果的深度评述
Lipanjali Badhei,Debashis Mishra,Prafulla Nandi et al.
Lipanjali Badhei et al.
The development of self-micro-emulsifying drug delivery system (SMEDDS) has revolutionized pharmaceutical formulation by providing an advanced method of increasing medication bioavailability and therapeutic effectiveness. The systems encaps...
Bouraoui Ouni,Ferdaous Chahed,Raoudha Slim et al.
Bouraoui Ouni et al.
Introduction: Certolizumab (CZ) is a tumour necrosis factor-α (TNF-α) blocking agent with excellent efficiency in rheumatoid arthritis (RA). Urticarial vasculitis (UV) induced by CZ is a rare side effect. Herein, we des...
Clinical Manifestations of Neuropathic Pain and the Deleterious Effects of Chemotherapeutic Agents [0.03%]
神经性疼痛的临床表现以及化疗药物的有害影响
Moumita Ghosh,Manodeep Chakraborty,Ananya Bhattacharjee et al.
Moumita Ghosh et al.
Neuropathic pain is a type of pain resulting from damage or dysfunction of the nervous system. Chemotherapy-induced peripheral neurotoxicity (CIPN) is a serious complication of cancer treatment, often occurring in a dose-dependent manner. C...
Revealing the Future of Pharmacovigilance in Precision Pharmaceutical Monitoring [0.03%]
揭示精准药物监测中药品警戒的未来
Vishnu Mittal,Anjali Sharma
Vishnu Mittal
The growing popularity of personalized medicine presents new hazards and difficulties for pharmacovigilance. This implies that it needs to modify its current approach. This research examines how drug safety monitoring for certain medication...
Managing Opioid Tolerance: Balancing Pain Relief and Tackling Addiction [0.03%]
管理阿片类药物耐受性：平衡镇痛和治疗成瘾的问题
Astha Mehta,Anunav Ashish,Shubham Thakur
Astha Mehta
This editorial discusses opioid tolerance, a growing challenge in managing pain in chronic patients. With time, overuse of opioids causes less sensitivity and responsiveness of opioid receptors and leads to higher doses of opioids for the s...
Ariba Sabat,Aakriti Garg,Mohd Ashif Khan
Ariba Sabat
Insomnia is becoming a concern in general practice as it affects around 30% of adults. It is a sleep disorder characterized by trouble getting asleep, staying asleep, waking up early, and difficulty falling back to sleep. The most commonly ...
A Biochemical Investigation of the Prevalence of Hypercalcemia and Thiazide-Related Hypercalcemia in Patients [0.03%]
高钙血症和噻嗪类利尿药相关高钙血症的生化检测研究
Shariq Rashid Masoodi,Moomin Hussain Bhat,Imtiyaz Ahmed Najar et al.
Shariq Rashid Masoodi et al.
Objective: Hypercalcemia allied with thiazide diuretics is a widely acknowledged clinical presentation. Hence, the purpose of this investigation was to ascertain the prevalence of hypercalcemia and hypercalcemia linked to...
Opioid Use Disorders: Prevention, Diagnosis, and Treatment Strategies to Mitigate Addiction Risks [0.03%]
阿片类使用障碍：预防、诊断及治疗策略以降低成瘾风险
Uma Agarwal,Khushboo Singhal,Rajiv Kumar Tonk
Uma Agarwal
Opioid Use Disorder (OUD) is defined by the persistent use of opioids despite adverse consequences. It is associated with increased mortality and a variety of mental and general medical comorbidities. Risk factors include younger age, male ...