Assessment of Iguratimod's Efficacy and Safety in Rheumatoid Arthritis: A Prospective, Open-Label Study [0.03%]
伊鲁替莫德治疗类风湿性关节炎有效性和安全性的前瞻性、开放标签研究
B Banupriya,Sulthan Al Rashid,Preetha Selva
B Banupriya
Objective: This study investigates the therapeutic effectiveness and safety profile of iguratimod (IGU) in patients with moderate to severe pain due to active rheumatoid arthritis (RA), utilizing the Disease Activity Scor...
Nirmatrelvir-Ritonavir (Paxlovid) in Patients with Epilepsy: A Focus on Drug-Drug Interactions [0.03%]
尼马曲韦-利托那韦（帕克斯洛维德）在癫痫患者中的应用：关注药物相互作用
Gianmarco Marcianò,Cristina Vocca,Antonio Siniscalchi et al.
Gianmarco Marcianò et al.
Introduction: There is growing interest in identifying drug interactions between Paxlovid (nirmatrelvir/ritonavir), an antiviral drug used for the management of outpatients with mild to moderate coronavirus disease, and a...
Prospective Assessment of Body Composition Changes with Sodium Glucose Transporters 2 (SGLT2) Inhibitors in Type 2 Diabetes Mellitus Using Bioelectrical Impedance Analysis [0.03%]
应用生物电阻抗分析前瞻性评估钠-葡萄糖协同转运蛋白2(SGLT2)抑制剂对2型糖尿病患者身体组成的影响
Bharti Bhandari,Preeti Kaliramana,Prerna Agarwal et al.
Bharti Bhandari et al.
Introduction: Type 2 Diabetes Mellitus (T2DM) very often leads to adverse changes in body composition, including increased fat mass and sarcopenic obesity. Sodium-Glucose Co- Transporter 2 inhibitors are effective hypogly...
In Vitro Evaluation of Simvastatin Nanoparticle-Coated Implant Healing Abutments: Cytotoxicity and Antibacterial Properties [0.03%]
体外评估西立伐他汀纳米粒包覆的种植体愈合基台：细胞毒性和抗菌性能
Ali Torab,Zoleikha Asadi,Mohammad Yousef Memar et al.
Ali Torab et al.
Introduction: Simvastatin is a lipid-lowering drug with pleiotropic effects. Several studies have shown that it may have a protective effect on reducing morbidity and mortality from infections. One of the most devastating...
Itraconazole-Induced Motor Sensory Polyneuropathy in a Young Indian Male: An Unusual Case [0.03%]
特康唑诱导的一例年轻印度男性患者的运动感觉多发性神经病：罕见病例报告
Jitendra Singh,Pooja Chaurasiya,Anju Dinkar et al.
Jitendra Singh et al.
Introduction: Itraconazole, a widely prescribed triazole antifungal agent, is generally well tolerated but can rarely cause neurotoxicity. Motor-sensory polyneuropathy secondary to itraconazole use is an exceptionally unc...
Different Therapeutic Doses of Sertraline Induce Liver Damage in Male Rats [0.03%]
不同剂量的舍曲林致大鼠肝损伤作用及机制研究
Maryam Beigmohamadi,Khairollah Asadollahi,Amir Adibi et al.
Maryam Beigmohamadi et al.
Introduction: Sertraline is a first-line pharmacological treatment for Major Depressive Disorder (MDD) but can cause adverse effects, including acute hepatitis. This study aims to investigate, using an experimental male r...
Neurological Complications of Prolonged Metronidazole Therapy: A Case of Reversible Encephalopathy [0.03%]
长期甲硝唑治疗的神经系统并发症：可逆性脑病一例
Akramraza A Govani,Bhargav M Purohit,Jaimish S Patel et al.
Akramraza A Govani et al.
Introduction: Metronidazole-induced encephalopathy (MIE) is a rare but potentially reversible adverse effect associated with prolonged metronidazole use. ...
Mohammed Danish Anwar,Ajita Kapur,Kapil Hazarika et al.
Mohammed Danish Anwar et al.
Background: Linezolid is an oxazolidinone antibiotic widely prescribed for actinomycetoma. Haematological adverse reactions, such as thrombocytopenia, have been widely reported due to linezolid. We report an unusual case ...
Is "More" Always Better than "Less"? Deprescribing to Improve Patients' Clinical Outcomes: A Case Series [0.03%]
“减”是否总比“加”差？减少用药改善患者的临床结局：一系列病例报告
Pietro Gareri,Gianmarco Marcianò,Antonio Siniscalchi et al.
Pietro Gareri et al.
Introduction: Polypharmacy represents a significant clinical concern, particularly among elderly patients, due to the increased risk of adverse drug reactions (ADRs). This population is often affected by multiple comorbid...
Magnitude and Predictors of Antimicrobial Use-Related Drug Problems in Geriatric Inpatients: Evaluation of Pharmacist Interventions [0.03%]
老年住院患者抗菌药物相关用药问题的现状、影响因素及药师干预效果评估
Mian Waqar Hussain,Jisha Myalil Lucca,Shabaz Mohiuddin Gulam et al.
Mian Waqar Hussain et al.
Introduction: Infections remain a major cause of illness and death in older adults. Physiological changes, polypharmacy, and chronic conditions complicate antimicrobial therapy and increase the risk of drug problems. Phar...