Buzhong Yiqi Decoction Regulates Th17 Cells Differentiation in Autoimmune Thyroiditis through PTEN/AKT-immunometabolism Axis [0.03%]
补中益气汤通过PTEN/AKT-免疫代谢轴调节自身免疫性甲状腺炎Th17细胞分化
Jia-Yun Li,Zhuo Zhao,Dong-Lin Liu et al.
Jia-Yun Li et al.
Introduction: Autoimmune thyroiditis (AIT), a prevalent autoimmune disorder, can severely impair patients' quality of life when progressing to hypothyroidism. This investigation seeks to systematically evaluate the therapeutic efficacy of B...
Immune-Mitochondrial Crosstalk in Pancreatic Adenocarcinoma: Systematic Identification of Prognostic Biomarkers Through Immune Dictionary Framework [0.03%]
基于免疫词典框架系统识别胰腺导管腺癌预后生物标志物的免疫-线粒体互作研究
Jiangang Zhao,Fenglin Zhang,Xinghe Liao et al.
Jiangang Zhao et al.
Introduction: Pancreatic adenocarcinoma (PAAD) is characterized by aggressive progression, driven by an immunosuppressive tumor microenvironment (TME) and mitochondrial dysfunction. Alterations in mitochondrial bioenergetics and metabolic r...
Single-Cell Profiling Identifies JUNB/SPI1-Driven Inflammatory Programs and Novel Communication Axes in Myeloid Cells of Sepsis [0.03%]
单细胞测序鉴定出败血症髓系细胞中JUNB/SPI1驱动的炎症程序及新的通讯轴线
Liyao Liu,Lin Zhao,Jixiang Tan
Liyao Liu
Introduction: Sepsis is a Systemic Inflammatory Response (SIR) caused by invading pathogens. We aimed to characterize infiltrating cells in sepsis and provide novel insight for the treatment of sepsis. ...
Simone Antonio De Sanctis,Sabrina Chiloiro,Antonella Giampietro et al.
Simone Antonio De Sanctis et al.
Background: Acromegaly associated with Morris syndrome has never been reported in the literature. Case presentation: We present the cas...
VNN2 and IL1R2 Identified as Potential Molecular Signatures in Granulosa Cells and Blood of Patients with Polycystic Ovary Syndrome (PCOS) [0.03%]
VNN2和IL1R2作为多囊卵巢综合征颗粒细胞和血液中潜在分子标志物的鉴定
Zahraa Alali
Zahraa Alali
Introduction: PCOS is a common endocrine disorder in women of reproductive age, with granulosa cells playing a key role in its development. This study aims to identify shared differentially expressed genes (DEG) in granul...
Network Pharmacology and Molecular Docking Reveal the Multi-Target Anti-Osteoporosis Mechanism of Bushen Huoxue Decoction [0.03%]
网络药理学和分子对接揭示补肾活血方治疗骨质疏松的多靶点作用机制研究
Hongtao Li,Hongyu Pan,Minshan Feng
Hongtao Li
Introduction: Traditional Chinese medicine, especially Bushen Huoxue decoction, has demonstrated good therapeutic effects in the treatment of intervertebral disc degeneration and osteoarthritis, but its mechanism of actio...
Functions of Estrogen and Estrogen-Related Receptors in Diseases of the Female Reproductive System [0.03%]
雌激素和雌激素受体相关蛋白在女性生殖系统疾病中的作用
Jinzheng Wang,Ziming Zhu,Liding Fan et al.
Jinzheng Wang et al.
Diseases of the female reproductive system are prevalent. These conditions often have a high proportion of asymptomatic patients and prolonged treatment durations. Estrogen, a crucial steroid hormone, plays a central role in most diseases o...
Pseudoexfoliation Glaucoma Selective Laser for Trabeculoplasty Treatment in Vietnam [0.03%]
伪醛固酮症性青光眼选择性激光小梁成形术治疗在越南的应用
Thanh Doan Kim,To Tran Ke,Anh Tran Cong et al.
Thanh Doan Kim et al.
Introduction: To evaluate the effectiveness of selective laser trabeculoplasty (SLT) in lowering intraocular pressure (IOP) in Vietnamese patients with pseudoexfoliation glaucoma (PXG). ...
Nonlinear Association Between Uric Acid to High-Density Lipoprotein Cholesterol Ratio and Diabetic Kidney Disease: Evidence from NHANES 2007-2018 [0.03%]
尿酸与高密度脂蛋白胆固醇比值和糖尿病肾脏疾病的非线性关联：来自NHANES 2007-2018的数据证据
Yi Wei,Chao Liu,Jiangyi Yu
Yi Wei
Introduction: The relationship between uric acid to high-density cholesterol ratio (UHR) and diabetic kidney disease (DKD) is unclear. The aim of this study was to investigate the relationship between UHR and DKD in patie...
Anti-inflammatory and Antioxidant Effects of Silibinin on Valproate-Induced Pancreatitis in Male Wistar Rats [0.03%]
白术对丙戊酸诱导的雄性Wistar大鼠胰腺炎的抗炎和抗氧化作用
Mohammad Hady Khosravi,Khairollah Asadollahi,Bahareh Ghiasi et al.
Mohammad Hady Khosravi et al.
Introduction: Valproic acid (VPA), a widely used antiepileptic drug, is associated with pancreatic toxicity. Silibinin, the active component of silymarin, exhibits antioxidant/anti-inflammatory properties. This study inve...