Identification of Lactate-related Biomarkers in Non-alcoholic Fatty Liver Disease [0.03%]
非酒精性脂肪性肝病相关乳酸生物标志物的识别
Qingxuan He,Xu Wang,Pengfei Wang et al.
Qingxuan He et al.
Background: Nonalcoholic fatty liver disease (NAFLD) is characterized by profound metabolic reprogramming. Recent evidence suggests that lactate, beyond its role as a metabolic waste product, may modulate histone lactylat...
A Study on the Correlation between Circulating Paraoxonase 1 Levels and Coronary Artery Stenosis in Diabetic Patients [0.03%]
糖尿病患者血清Paraoxonase 1活性与冠状动脉狭窄程度相关性研究
Yu Zhao,Yan Wang,Lin Mao et al.
Yu Zhao et al.
Objective: Research has found that paraoxonase 1 (PON1) is closely related to cardiovascular disease, but the relationship between circulating PON1 levels and coronary artery stenosis (CAS) in patients with diabetes remai...
Relationship Between Comprehensive Inflammatory Indicators and Gout Risk: A Cross-sectional Study Based on NHANES 2015-2018 [0.03%]
基于NHANES 2015-2018的横断面研究：全面炎症指标与痛风风险之间的关系
Fan Zeng,Ou Mei,Min Lu et al.
Fan Zeng et al.
Introduction: Gout development and progression are closely linked to inflammatory processes. Six novel systemic inflammation indices, including the neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index ...
Age and Gender on the Efficacy of Metabolic Surgery in Patients with Obesity and Type 2 Diabetes [0.03%]
代谢手术治疗肥胖合并2型糖尿病患者的疗效与年龄和性别的关系
Bo Ma,Yangfan Dong,Tao Li et al.
Bo Ma et al.
Introduction: This study aims to investigate the influence of age and gender on the efficacy of metabolic surgery in patients with obesity with type 2 diabetes mellitus (T2DM). ...
Persistently Elevated Serum IgM: A Diagnostic Red Flag for Primary Immunodeficiencies: A Case-Based Review and Clinical Approach [0.03%]
持续升高的血清IgM：原发性免疫缺陷诊断的警示标志：基于病例的回顾和临床方法分析
Cristina Tomacinschii,Svetlana Sciuca,Mihaela Bataneant et al.
Cristina Tomacinschii et al.
Introduction/objective: Persistently elevated serum immunoglobulin M (IgM) is commonly interpreted as a marker of acute infection, autoimmune activity, or lymphoproliferation. Sustained IgM elevation may represent an unde...
Shi Pi Shu Gan Formula Prevents and Treats Sequelae of Pelvic Inflammatory Disease by Regulating PKA-CREB-Yap1 Signaling through the mtDNA/cGAS/STING Network [0.03%]
调教母线PKA-CREB-YAP1信号防止和治疗盆腔炎性疾病后遗症的 Shi Pi Shu Gan Formula的作用机制研究
Yuyang Mi,Haiqing He,Yefang Huang et al.
Yuyang Mi et al.
Objective: To investigate the effects and mechanisms of Shi Pi Shu Gan formula (SPSGF) on sequelae of pelvic inflammatory disease (SPID) in rats with liver stagnation and spleen deficiency. ...
Inflammation-related Genes as Potential Shared Biomarkers for Metabolic Dysfunction-associated Fatty Liver Disease and Acute Pancreatitis [0.03%]
与代谢功能紊乱相关脂肪肝病和急性胰腺炎共享的生物标志物潜在候选基因的研究
Kang Gong,Jialing Jiang,Yifan Zhang et al.
Kang Gong et al.
Background: People with Acute Pancreatitis (AP) who also have Metabolic Dysfunctionassociated Fatty Liver Disease (MAFLD) are more likely to experience worse consequences. However, the mechanisms that link MAFLD and AP ar...
IGFBP2 Knockdown Ameliorates Diabetic Gastroparesis by Inhibiting VDAC1-Dependent Mitophagy in Interstitial Cells of Cajal [0.03%]
通过抑制Cajal间质细胞中VDAC1依赖的线粒体自噬缓解糖尿病胃轻瘫及IGFBP2沉默的作用机制研究
Xiao Yuan,Yuting Chen,Zhengran Qin et al.
Xiao Yuan et al.
Introduction/objective: Although insulin-like growth factor binding protein 2 (IGFBP2) is significantly upregulated in diabetic gastroparesis (DGP) and may regulate ICC mitophagy through its interaction with VDAC1, the pr...
Identifying the Oxidative Stress-related Hub Genes in Dilated Cardiomyopathy by Bioinformatics Analysis [0.03%]
生物信息学分析鉴定扩张型心肌病的氧化应激相关关键基因
Ruifeng Cao,Junchen Ji,Yaling Wang
Ruifeng Cao
Introduction: Characterized as an idiopathic primary myocardial disorder, dilated cardiomyopathy (DCM) predominantly affects children and elderly adults. However, a lack of specific clinical symptoms and reliable biomarke...
The Causal Relationship between Antibody Immune Response and Ischemic Stroke: A Mendelian Randomization Analysis [0.03%]
抗体免疫反应与缺血性卒中的因果关系：孟德尔随机化分析
Chunshu Rong,Zhen Wei,Yuetong Zhao et al.
Chunshu Rong et al.
Introduction: Recognizing the risk factors associated with Ischemic Stroke (IS) is essential for its prevention. Currently, there are no studies exploring the causal link between antibodymediated immune responses and IS. ...