A Case Report of Anti-GAD65 Antibody-Positive Autoimmune Encephalitis Associated with Diabetes [0.03%]
与糖尿病相关的抗GAD65抗体阳性自身免疫性脑炎病例报告
Xiuping Xuan,Liheng Meng,Lulu Chen et al.
Xiuping Xuan et al.
Background: Patients with GAD65 antibody-associated autoimmune encephalitis who also have diabetes are usually considered to have type 1 diabetes mellitus (T1DM). However, previous reports often lacked β-cell function as...
Comprehensive Review on the Protective Effects of Lycium barbarum Polysaccharide on Neurodegenerative Diseases [0.03%]
枸杞多糖对神经退行性疾病保护作用的研究进展综述
Qingxin Lu,Xin Di,Xiaoli Guo
Qingxin Lu
Neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, Huntington's disease, ischemic stroke, and other related conditions, significantly impact the quality of life, particularly in low-income nations. The pathogenes...
Integrative Multi-Omics Deciphering of Gu Shu Kang Granules: A Comprehensive Systems Biology Approach to Unraveling Molecular Mechanisms in Sarcopenia-Osteoporosis Intervention [0.03%]
骨嵩康颗粒整合多组学解析及其干预肌少-骨质疏松症分子机制的系统生物学研究
Xiangran Cui,Zhitong Yu,Deyu Wang et al.
Xiangran Cui et al.
Introduction: Sarcopenia is a degenerative musculoskeletal disease affecting the elderly, significantly impairing patients' quality of life and challenging modern medicine. This study innovatively combines Traditional Chi...
Role of the lncRNA MALAT1/miR-1 Pathway in Mouse Myocardial Ischemia-Reperfusion Injury [0.03%]
长链非编码RNA MALAT1/miR-1信号通路在小鼠心肌缺血再灌注损伤中的作用机制研究
Jiangen Liu,Bin Zhang,Jinlei Li et al.
Jiangen Liu et al.
Introduction: The interplay between LncRNA MALAT1 and hsa-miR-1 plays a crucial role in Myocardial Ischemia-Reperfusion Injury (MIRI), offering insights into the molecular mechanisms underlying cardiovascular pathologies....
17β-Estradiol Improves Liver Function in T2DMNAFLD Mice via PGC-1α/ERRα Axis Activation While Preserving Cholestatic Safety [0.03%]
雌二醇通过激活PGC-1α/ERRα信号轴改善T2DM伴NAFLD小鼠的肝功能而不加重胆汁淤积安全指标异常
Wangwei Xu,Qiaoyun Ni,Qingqing Yang et al.
Wangwei Xu et al.
Introduction: This study investigated the hepatoprotective effects and mechanisms of 17β-estradiol (E2) in a mouse model of type 2 diabetes mellitus (T2DM) with non-alcoholic fatty liver disease (NAFLD). ...
Association Between Irritable Bowel Syndrome and Hypothyroidism: Insights from Large-Scale Population-Based Studies [0.03%]
基于大规模人群的队列研究探究肠易激综合征与甲状腺功能减退症的关系
Jing Wu,Ziwei Liu,Luna Liu et al.
Jing Wu et al.
Introduction: Irritable Bowel Syndrome (IBS) and hypothyroidism are both common conditions that significantly affect patient health. This study examines the link between IBS and hypothyroidism, focusing on how IBS impacts...
LGI1 Antibody-Associated Encephalitis Complicated with Sjögren's Syndrome and Acute Cerebral Infarction: A Case Report and Literature Review [0.03%]
抗LGi1脑炎合并舍格伦综合征及急性脑梗死一例及相关文献复习
Dongxiao Jiang,Yanfen Lian,Xia Zhan et al.
Dongxiao Jiang et al.
Background: Anti-LGI1 antibody-associated encephalitis is a rare autoimmune neurological disorder, and primary Sjögren's syndrome is a systemic autoimmune disease with multisystem involvement. The coexistence of these co...
Heterogeneous Hemostatic Disorder Associated with IgA Monoclonal Gammopathy: A Case Series [0.03%]
与IgA单克隆丙球蛋白血症相关的异质性止血缺陷：一系列病例研究
Cheng-Wei Huang,Guan-Min Lai,Ching-Yeh Lin et al.
Cheng-Wei Huang et al.
Introduction: Monoclonal gammopathy, or paraproteinemia, involves monoclonal immunoglobulins in the blood and ranges from benign monoclonal gammopathy of undetermined significance (MGUS) to malignant multiple myeloma. Hem...
Bioinformatics-based Mechanisms of Lipid Metabolism and Endoplasmic Reticulum Stress in Coronary Artery Disease [0.03%]
基于生物信息学的冠状动脉疾病中脂质代谢及内质网应激机制研究
Lili Ye,Huaiyu Ruan,Qinyun Chen et al.
Lili Ye et al.
Introduction: Lipid metabolism and endoplasmic reticulum stress (ERS) are crucial in coronary artery disease (CAD) pathogenesis, but the exact mechanisms remain unclear. This study aims to systematically investigate the m...
Causal Links Between Antibody-Mediated Immune Responses and Pancreatic Cancer Risk [0.03%]
抗体介导的免疫反应与胰腺癌风险间的因果关系
Xinyun Zou,Yicheng Feng,Pei Liu et al.
Xinyun Zou et al.
Introduction: Pancreatic cancer (PC) presents unique challenges to traditional immunotherapy due to its immunosuppressive microenvironment and low mutation burden. Research into antibody-mediated immune responses, which h...