In vitro and in silico evaluation of Andrographis paniculata ethanolic crude extracts on fatty acid synthase expression on breast cancer cells [0.03%]
安宫薄荷醇提取物对乳腺癌细胞中脂肪酸合成酶表达的体外和计算机模拟评价
Nur Amanina Johari,Nur Anisa Sapi&#x;i,Alvin Lu Jiunn Hieng et al.
Nur Amanina Johari et al.
Background: Fatty acid synthase (FASN), a key rate-limiting enzyme in the fatty acid biosynthesis pathway has been identified to be overexpressed in breast cancer. This overexpression has been affiliated with poor prognos...
Protection of Gueichih-Fuling-Wan on cerebral ischemia-induced brain injury in rodents is mediated by trans-cinnamaldehyde via inhibition of neuroinflammation and apoptosis [0.03%]
桂附 Warm Tonifying the Kidney Yang Formulation对啮齿类脑缺血损伤的保护作用由trans-肉桂醛通过抑制神经炎症和凋亡介导
Yuh-Fung Chen,Kuo-Jen Wu,Chi-Chung Kuo et al.
Yuh-Fung Chen et al.
Background: Stroke is the leading cause of mortality and morbidity worldwide, and an effective therapeutic strategy for the prevention of patients with cerebral ischemia induced brain injury is lacking. Traditional Chines...
Unveiling the power of flavonoids: A dynamic exploration of their impact on cancer through matrix metalloproteinases regulation [0.03%]
黄酮类化合物的力量：通过基质金属蛋白酶调节探讨其对癌症的影响动态探究
Peramaiyan Rajendran
Peramaiyan Rajendran
Cancer stands as a significant contributor to global mortality rates, primarily driven by its progression and widespread dissemination. Despite notable strides in cancer therapy, the efficacy of current treatment strategies is compromised d...
Phytochemical composition of Clinacanthus nutans based on factors of environment, genetics and postharvest processes: A review [0.03%]
Clinacanthus nutans的植物化学成分基于环境、遗传和采后因素：综述
Nurul H Sabindo,Rusidah M Yatim,P Kannan Thirumulu
Nurul H Sabindo
Herpes simplex, varicella-zoster lesions, skin rashes, diabetes, snake bites and insect bites have all been treated by using Clinacanthus nutans (C. nutans). The pharmacological effects of C. nutans are influenced by the presence of terpeno...
Zinc oxide nanoparticles-doped curcumin-assisted recovery of rheumatoid arthritis and antioxidant status in experimental rabbits [0.03%]
纳米氧化锌粒子增强姜黄素辅助治疗实验性兔类风湿关节炎和抗氧化状态的研究
Shanza Azeez,Mishal Fatima,Ouz Gul et al.
Shanza Azeez et al.
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation and synovial joint destruction. Aims: ...
Biomedicines in Longevity and Aging the Quest to Resist Biological Decline [0.03%]
抗衰老生物药物：延缓机体生物学衰退的探索之旅
Raymond D Palmer
Raymond D Palmer
Aging is considered part of the natural process of life, however in recent years medical literature has started to show that specific facets of aging are beginning to be understood and those factors may even be considered preventable with v...
Impact and prevalence of comorbidities and complications on the severity of COVID-19 in association with age, gender, obesity, and pre-existing smoking: A meta-analysis [0.03%]
关于年龄、性别、肥胖和既往吸烟与COVID-19严重程度相关联的共病和并发症的影响和流行率的meta分析
Soulandi Djorwé,Amale Bousfiha,Néhémie Nzoyikorera et al.
Soulandi Djorwé et al.
Background: COVID-19 patients usually present multiple comorbidities and complications associated with severe forms of SARS-CoV-2 infection. This study aimed to assess the risk factors and prevalence of comorbidities and ...
A brief literature review of low-level laser therapy for treating amyotrophic lateral sclerosis and confirmation of its effectiveness [0.03%]
低水平激光疗法治疗肌萎缩侧索硬化症的文献综述及其有效性的确认
Sergey V Moskvin
Sergey V Moskvin
Introduction: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with a steadily progressive course due to the death of central and peripheral motor neurons responsible for voluntary movements. Low-level l...
VKORC1 polymorphisms and complete resistance to vitamin K antagonists: About two cases [0.03%]
VKORC1多态性与维生素K拮抗剂完全耐药的关系：2例报告
Ilham Benyamna,Houda El Fissi,Fadoua Bouzid et al.
Ilham Benyamna et al.
Complete resistance to vitamin K antagonists is a rare but serious condition. It can complicate therapeutic management, especially when direct oral anticoagulants cannot be used. Some single mutations in the VKORC1 gene have been identified...
Case Reports
BioMedicine. 2024 Mar 1;14(1):60-63. DOI:10.37796/2211-8039.1434 2024
Computational analysis of dimer G6PD structure to elucidate pathogenicity of G6PD variants [0.03%]
计算分析二聚体G6PD结构以阐明G6PD变异体的致病性
Shamini Chandran,Naveen Eugene Louis,Syazwani Itri Amran et al.
Shamini Chandran et al.
An inherent genetic enzyme disorder in humans, known as glucose-6-phosphate dehydrogenase (G6PD) deficiency, arises due to specific mutations. While the prevailing approach for investigating G6PD variants involves biochemical analysis, the ...