Hepatoprotective evaluation of benzoylated emodin derivatives: Integrating bioinformatics and in vitro studies [0.03%]
苯甲酸化芦荟大黄素衍生物的肝保护作用评价：结合生物信息学与体外实验研究
Firdayani,Putri Hawa Syaifie,Siska Andrina Kusumastuti et al.
Firdayani et al.
Background: Emodin exhibits various pharmacological activities, including hepatoprotective effects. However, its clinical application is limited by poor absorption and low oral bioavailability. This study aimed to optimiz...
Chao-Hsuan Chen,Wen-Shin Chang,Chia-Wen Tsai et al.
Chao-Hsuan Chen et al.
Introduction: Genetic polymorphisms in DNA repair pathways can modulate DNA repair capacity and influence susceptibility to aging-related disorders, including Parkinson's disease (PD). This study evaluated the association...
Unveiling immune-related gene signatures in triple negative breast cancer through integrated transcriptomic analysis [0.03%]
通过整合转录组分析揭示三阴性乳腺癌中的免疫相关基因特征
Priyanga Paranthaman,Ramanathan Karuppasamy,Shanthi Veerappapillai
Priyanga Paranthaman
Background: Triple-negative breast cancer (TNBC) is an aggressive subtype with limited treatment options and poor prognosis. Understanding the underlying molecular mechanisms, particularly immune-related gene networks, is...
Early-life exposure to antibiotics increases the risk of myopia: A retrospective cohort study [0.03%]
幼年时期接触抗生素增加近视风险：一项回顾性队列研究
Peng-Tai Tien,Chang-Ching Wei,Sheng-Chun Lin et al.
Peng-Tai Tien et al.
Background: The prevalence of myopia is increasing worldwide and is projected to affect nearly half of the global population by 2050. Although genetic susceptibility plays an important role, early-life environmental expos...
The adverse effects of clozapine on blood markers and electrocardiographic findings in patients with schizophrenia [0.03%]
氯氮平对精神分裂症患者血液标志物和心电图结果的不良影响
Papageorgiou Anastasios,Vrettou Christina,Koukouli Andriana et al.
Papageorgiou Anastasios et al.
Introduction: Clozapine remains the gold-standard antipsychotic for treatment-resistant schizophrenia, but its use is hindered by rare but serious adverse effects, such as hematologic abnormalities and myocarditis. ...
Traditional Chinese herbal medicines suppress endometriosis development through modulating macrophage-mediated immune responses in the peritoneal cavity [0.03%]
传统中药通过调节腹腔巨噬细胞介导的免疫反应来抑制子宫内膜异位症的发展
Cherry Yin-Yi Chang,Kung-Pin Chang,Pei-Fen Lee et al.
Cherry Yin-Yi Chang et al.
Background: Due to unique dietary culture, Asian patients with endometriosis usually seek assistance through traditional Chinese herbal medicine (TCHM), making combined treatments of Western and Chinese medicine quite com...
Evaluation of Bai-Zhu (Atractylodes macrocephala)-based herbal formulae in breast cancer: Implications for metastasis via Zeb1 and Slug modulation [0.03%]
白术抗乳腺癌转移的中药复方筛选及机制研究
Yen Shen Lu,Pei Yen Yeh,Ling-Chun Yeh et al.
Yen Shen Lu et al.
Background: Bai-Zhu (Atractylodes macrocephala Koidz. [Asteraceae]) is classified in traditional Chinese medicine (TCM) as an herb that targets the gastric and pancreatic meridians to support normal nutrient uptake. As su...
Chinese herbal medicine treatment and the association with long-term major adverse cardiac events in patients with chronic kidney disease: A propensity-score matched cohort study [0.03%]
基于倾向评分匹配的队列研究：中药治疗与慢性肾病患者长期主要心血管不良事件的关系
Yuan-Ching Liao,Mei-Yao Wu,Cheng-Li Lin et al.
Yuan-Ching Liao et al.
Background: Cardiovascular disease (CVD) represents the leading cause of mortality among individuals with chronic kidney disease (CKD). While Chinese herbal medicine (CHM) is commonly used by CKD patients in Taiwan, the i...
Adjunctive hyperbaric oxygen therapy for chronic diabetic foot ulcer unresponsive to standard care: A case report [0.03%]
高压氧作为糖尿病足溃疡的辅助治疗手段用于常规治疗方法无效的慢性糖尿病足溃疡的案例报告
Sukriyadi Adi,Ismail Ismail,Sitti Rahmatiah et al.
Sukriyadi Adi et al.
Background: Diabetic foot ulcers (DFUs) are a serious complication of diabetes mellitus and are often challenging to treat, particularly in patients who fail to respond to standard wound care. Adjunctive therapies such as...
Case Reports
BioMedicine. 2026 Mar 1;16(1):69-74. DOI:10.37796/2211-8039.1693 2026
Decyl caffeate inhibits the proliferation of human triple negative breast cancer cells [0.03%]
癸基咖啡酸酯可抑制人类三阴性乳腺癌细胞的增殖
Che-Yi Chao,Woei-Cheang Shyu,Chih-Lung Lin et al.
Che-Yi Chao et al.
Background: Over recent decades, considerable attention has been directed toward the discovery of novel compounds capable of targeting survival-related signaling networks as therapeutic candidates for triple-negative brea...