Mass spectrometry-based proteomics in Chest Medicine, Gerontology, and Nephrology: subgroups omics for personalized medicine [0.03%]
基于质谱的蛋白质组学在胸科医学、老年病学和肾病学中的应用：子组学在个性化医学中的作用
Shih-Yi Lin,Wu-Huei Hsu,Cheng-Chieh Lin et al.
Shih-Yi Lin et al.
Mass spectrometry (MS) is currently the most promising tool for studying proteomics to investigate largescale proteins in a specific proteome. Emerging MS-based proteomics is widely applied to decipher complex proteome for discovering poten...
New mechanisms of antiplatelet activity of nifedipine, an L-type calcium channel blocker [0.03%]
硝苯地平的新抗血小板作用机制：一种L型钙通道阻滞剂
Tz-Chong Chou
Tz-Chong Chou
Platelet hyperactivity often occursd in hypertensive patients and is a key factor in the development of cardiovascular diseases including thrombosis and atherosclerosis. Nifedipine, an L-type calcium channel blocker, is widely used for hype...
Molecular targets for anti-oxidative protection of green tea polyphenols against myocardial ischemic injury [0.03%]
绿茶多酚抗心肌缺血氧化损伤的作用靶点研究进展
Shih-Rong Hsieh,Wei-Chen Cheng,Yi-Min Su et al.
Shih-Rong Hsieh et al.
Ischemic heart disease is the leading cause of death worldwide. An improved understanding of the mechanisms involved in myocardial injury would allow intervention downstream in the pathway where certain drugs including natural products coul...
Mei-Chih Chen,Shih-Lan Hsu,Ho Lin et al.
Mei-Chih Chen et al.
Retinoic acid which belongs to the retinoid class of chemical compounds is an important metabolite of vitamin A in diets. It is currently understood that retinoic acid plays important roles in cell development and differentiation as well as...
Lii-Tzu Wu,Tsuei-Yuan Lai,Chiu-Shong Liu et al.
Lii-Tzu Wu et al.
Key ingredients for upgrading health care include bolstering and appraising professional medical education. Health examination as a crucial element of health care that we must incorporate into medical education. This research evaluates medi...
Polymorphism of gene cassette promoter variants of class 1 integron harbored in S. Choleraesuis and Typhimurium isolated from Taiwan [0.03%]
台湾分离的猪霍乱沙门氏菌和肠炎沙门氏菌中第1类整合子基因 cassette 启动子多态性研究
Chih-Sian Tseng,Yu-Chieh Yen,Chao-Chin Chang et al.
Chih-Sian Tseng et al.
Integrons, mobile genetic units, capture and incorporate antibiotic resistance gene cassette by site-specific recombination. Class 1 integrons are widespread and associated with dispersion of antibiotic resistance among Gram-negative bacter...
Anti-glycative effects of asiatic acid in human keratinocyte cells [0.03%]
羟基化合物 Asiatic Acid 的抗糖化功效及其对人类角质细胞影响机制研究
Zhi-Hong Wang
Zhi-Hong Wang
Background: Human skin keratinocyte (HaCaT) cells served to examine effects of asiatic acid (AA) at 1, 2, 4 and 8 μM against advanced glycative endproduct (AGE)-modified bovine serum albumin (BSA) induced glycative stress. Results: AGE-BSA...
Renal protective effects of Porphyra dentate aqueous extract in diabetic mice [0.03%]
干燥扁牙口红藻多糖对糖尿病小鼠的肾脏保护作用研究
Pei-Chun Chao,Cheng-Chin Hsu,Wen-Hu Liu
Pei-Chun Chao
Background: Purple laver ((Porphyra dentate) is a popular edible seaweed in Asia. This study examined protective effects of extract from purple laver extract (PLE) in diabetic mice. Methods: Content of carotenoids and anthocyanins in PLE wa...
Effect of wild bitter gourd treatment on inflammatory responses in BALB/c mice with sepsis [0.03%]
苦葫芦对败血症BALB/c小鼠炎性反应的影响
Shin-You Ciou,Cheng-Chin Hsu,Yueh-Hsiung Kuo et al.
Shin-You Ciou et al.
Background/Introduction: Wild bitter gourd (Momordica charantia L. var. abbreviate Seringe) common vegetable in Asia, is used in traditional medicine to treat various diseases, including inflammation. Extant literature indicates that wild b...
Tissue distribution of naringenin conjugated metabolites following repeated dosing of naringin to rats [0.03%]
重复给予柚皮素后大鼠组织中柚皮素结合型代谢物的分布研究
Shiuan-Pey Lin,Yu-Chi Hou,Shang-Yuan Tsai et al.
Shiuan-Pey Lin et al.
Background: Naringin is a major antioxidant in Citrus fruits and herbs. To clarify molecular forms distributed to various tissues, we investigated tissue distribution of naringin and relevant metabolites in rats after repeated dosing. Metho...