Chun-Jung Lin,Cheng-Kuo Lai,Min-Chuan Kao et al.
Chun-Jung Lin et al.
Cholesterol-rich microdomains (also called lipid rafts), where platforms for signaling are provided and thought to be associated with microbe-induced pathogenesis and lead to cancer progression. After treatment of cells with cholesterol dis...
Associations of EDNRA and EDN1 polymorphisms with carotid intima media thickness through interactions with gender, regular exercise, and obesity in subjects in Taiwan: Taichung Community Health Study (TCHS) [0.03%]
内皮素基因多态性与台湾受试者颈动脉内膜中层厚度的关联及其与性别、规律运动和肥胖的交互作用：台中社区健康研究(TCHS)
Tsai-Chung Li,Chia-Ing Li,Li-Na Liao et al.
Tsai-Chung Li et al.
The aim of this study was to evaluate the interacted association between EDNRA and EDN1 polymorphisms and gender, regular exercise, and obesity status on carotid intima media thickness (IMT) in community- dwelling subjects of the Taichung C...
Emerging roles of frailty and inflammaging in risk assessment of age-related chronic diseases in older adults: the intersection between aging biology and personalized medicine [0.03%]
脆弱性和炎症衰老在老年人群年龄相关慢性病风险评估中的新角色：老年医学和精准医学的结合点
I-Chien Wu,Cheng-Chieh Lin,Chao A Hsiung
I-Chien Wu
A chronic disease in older adults usually runs a course that is less predictable than in younger individuals. Unexplained variations in disease incidence, prognosis, therapeutic responses, and toxicity are frequently observed among older ad...
The bacterial interactions in the nasopharynx of children receiving adenoidectomy [0.03%]
扁桃体切除术儿童鼻咽部细菌相互作用分析
Hao-Xiang Chen,Chih-Ho Lai,Hui-Ying Hsu et al.
Hao-Xiang Chen et al.
Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae are the common pathogens that colonize in the nasopharynx of children. Polymicrobial interactions are thought to play an important role in different sites throughou...
Lipopolysaccharide-promoted proliferation of Caco-2 cells is mediated by c-Src induction and ERK activation [0.03%]
脂多糖促进的Caco-2细胞增殖由c-Src诱导和ERK活化介导
Tsung-Yao Lin,Chiung-Wen Fan,Ming-Chei Maa et al.
Tsung-Yao Lin et al.
As a major component of the cell wall of Gram-negative bacteria, lipopolysaccharide (LPS) can be released into the bloodstream to cause a spectrum of pathophysiological reactions. Despite the fact that colon epithelium cells in situ are con...
Irisflorentin improves α-synuclein accumulation and attenuates 6-OHDA-induced dopaminergic neuron degeneration, implication for Parkinson's disease therapy [0.03%]
irisflorentin改善α-突触核蛋白聚集并缓解6-羟基多巴胺诱导的多巴胺能神经元退行性变，对帕金森病治疗的意义
Yue-Mi Chen,Shih-Ping Liu,Hsin-Lien Lin et al.
Yue-Mi Chen et al.
Parkinson's disease (PD) is a degenerative disorder of the central nervous system that is characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta as well as motor impairment. Aggregation of α-synucle...
Sambucus williamsii induced embryonic stem cells differentiated into neurons [0.03%]
威氏接骨木诱导胚胎干细胞向神经细胞分化
Shih-Ping Liu,Chien-Yu Hsu,Ru-Huei Fu et al.
Shih-Ping Liu et al.
The pluripotent stem cells, including embryonic stem cells (ESCs), are capable of self-renewal and differentiation into any cell type, thus making them the focus of many clinical application studies. However, the efficiency of ESCs differen...
The current progress and future prospects of personalized radiogenomic cancer study [0.03%]
我国辐射基因组学癌症研究现状与未来展望
Juhn-Cherng Liu,Wu-Chung Shen,Tzu-Ching Shih et al.
Juhn-Cherng Liu et al.
During the last twenty years, mounting studies have supported the hypothesis that there is a genetic component that plays an important role in clinically observed variability in individual tissue/organ toxicity after radiotherapy. We propos...
Siew-Yin Chee,Chung-Hsing Wanga,Wei-De Lina et al.
Siew-Yin Chee et al.
Ectodermal dysplasia (ED) syndrome comprises a large, heterogeneous group of inherited disorders that are defined by primary defects in the development of 2 or more tissues derived from the embryonic ectoderm. The tissues primarily involved...
Lyophilized particles and ethanolic extracts of Antrodia cinnamomea mycelia suppress the tumorigenicity of head and neck cancer cells in vivo [0.03%]
紫衫灵芝菌丝冻干粉和乙醇提取物可抑制头颈部癌细胞的肿瘤发生能力
Ching-Wen Chang,Yu-Syuan Chen,Chien-Chih Chen et al.
Ching-Wen Chang et al.
Head and neck cancer (HNC) is one of the most common forms of cancer in Taiwan. In addition, head and neck cancer cells (HNCs) are highly tumorigenic and resistant to conventional therapy. Therefore, development of new therapeutic regimens ...