Emily Denne,Marie Moore Channell,Nicole White et al.
Emily Denne et al.
Down syndrome (DS) is a prevalent neurogenetic condition that impacts thousands of individuals, their families, and their communities each year. Due to the relatively high prevalence of DS and co-occurring conditions associated with this di...
A review of the literature on siblings of individuals with severe intellectual and developmental disabilities [0.03%]
关于重度智力和发育障碍个体的兄弟姐妹文献综述
Caroline L Roberts
Caroline L Roberts
Siblings of individuals with severe intellectual disability are underrepresented in research, yet they are simultaneously an at-risk population and a crucial population in terms of future planning (Heller & Arnold, 2010; Rossetti & Hall, 20...
Considerations for developing syndrome-informed early interventions for children with neurogenetic conditions [0.03%]
关于开发针对神经遗传病儿童的症状告知性早期干预的思考
Silvia Lanfranchi,Sara Onnivello,Madison Walsh et al.
Silvia Lanfranchi et al.
New insights regarding the early emergence of phenotypic patterns of strength and challenge in neurogenetic conditions afford the possibility of personalized, anticipatory intervention approaches. The development of novel 'syndrome-informed...
Cognitive outcome measures for tracking Alzheimer's disease in Down syndrome [0.03%]
唐氏综合征阿尔茨海默病认知评估方法
Victoria Fleming,Christy L Hom,Isabel C H Clare et al.
Victoria Fleming et al.
Down syndrome (DS) is now viewed as a genetic type of Alzheimer's disease (AD), given the near-universal presence of AD pathology in middle adulthood and the elevated risk for developing clinical AD in DS. As the field of DS prepares for AD...
Outreach and Engagement Efforts in Research on Down Syndrome: An NIH INCLUDE Working Group Consensus Statement [0.03%]
关于唐氏综合症研究中的推广和参与工作：NIH INCLUDE工作组共识声明
Deborah J Fidler,Nathaniel Riggs,Anna J Esbensen et al.
Deborah J Fidler et al.
The National Institutes of Health formulated the Outreach and Engagement Working Group in Fall of 2019 to support the objectives of the INCLUDE Project (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndrom...
Considerations for measuring individual outcomes across contexts in Down syndrome: Implications for research and clinical trials [0.03%]
唐氏综合症跨情境个体结果测量的考量：对研究和临床试验的影响
Anna J Esbensen,Emily K Schworer,Deborah J Fidler et al.
Anna J Esbensen et al.
Individuals with Down syndrome (DS) are increasingly involved in clinical trials that target developmental outcomes, like cognition and behavior. The increased focus on treatment in DS has led to ongoing discussions regarding the selection ...
Feasibility and acceptability of an online response inhibition cognitive training program for youth with Williams syndrome [0.03%]
威廉姆斯综合症青少年在线反应抑制认知训练程序的可行性与可接受性研究
Natalie G Brei,Ana-Maria Raicu,Han Joo Lee et al.
Natalie G Brei et al.
Williams syndrome (WS) is a genetic neurodevelopmental disorder often accompanied by inhibitory difficulties. Online cognitive training programs show promise for improving cognitive functions. No such interventions have been developed for i...
Neural Correlates of Sensory Abnormalities Across Developmental Disabilities [0.03%]
神经相关在发育障碍中的感觉异常
Garrett J Cardon
Garrett J Cardon
Abnormalities in sensory processing are a common feature of many developmental disabilities (DDs). Sensory dysfunction can contribute to deficits in brain maturation, as well as many vital functions. Unfortunately, while some patients with ...
Joint Attention and Early Social Developmental Cascades in Neurogenetic Disorders [0.03%]
神经遗传障碍中的共同关注和早期社会发育级联反应
Laura J Hahn
Laura J Hahn
This review examines what is known about joint attention and early social development in three neurogenetic syndromes: Down syndrome, Williams syndrome, and fragile X syndrome. In addition, the potential cascading effects of joint attention...
Anna J Esbensen,Amy J Schwichtenberg
Anna J Esbensen
Individuals with intellectual and developmental disabilities (IDD) experience sleep problems at higher rates than the general population. Although individuals with IDD are a heterogeneous group, several sleep problems cluster within genetic...