Report on the 4th FEBS-IUBMB-ENABLE International Molecular Biosciences PhD and Postdoc Conference 2025: "Bridging minds - Interdisciplinary research for the future of life sciences" [0.03%]
第4届FEBS-IUBMB-ENABLE国际分子生物科学博士和博士后大会2025报告：“汇聚智慧——生命科学研究的跨学科未来”
Manuel Lessi,Sara Gohar,Laura Martínez-Escardó
Manuel Lessi
The 4th International FEBS-IUBMB-ENABLE Molecular Biosciences PhD and Postdoc Conference, hosted by the Cancer Research UK Scotland Institute, was held from 10 to 12 September 2025 in Glasgow, United Kingdom. The theme of this year was Brid...
Supplement: FEBS-IUBMB-ENABLE 4th International Molecular Biosciences, PhD and Postdoc Conference BRIDGING MINDS, Interdisciplinary research for the future of life sciences, 10th-12th September 2025, CRUK Scotland Institute, Glasgow, United Kingdom [0.03%]
第四届FEBS-IUBMB-ENABLE博士和博士后会议补充通知：融会贯通，生命科学未来跨学科研究。2025年9月10日至12日，CRUK苏格兰研究所，英国格拉斯哥
Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A [0.03%]
定量蛋白组学分析揭示双酚A暴露对膀胱癌细胞的不同影响
Shaomin Niu,Lanlan Li,Wenjuan Jia et al.
Shaomin Niu et al.
Bisphenol A (BPA) is a widely used industrial chemical present in numerous consumer products such as plastics, epoxy resins, and thermal paper. Growing evidence suggests that BPA may pose potential health risks, particularly in relation to ...
Matrix metalloproteinase-9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells [0.03%]
基质金属蛋白酶-9调节卵巢癌细胞的细胞黏附和膜突起活性
Claire Strauel,Sam Bennett,Natalie Ehlinger et al.
Claire Strauel et al.
Matrix metalloproteinase-9 (MMP9), an extracellular endopeptidase, is upregulated by Epidermal Growth Factor (EGF) signaling and associated with ovarian epithelial cancer progression. To further understand the contribution of MMP9 to EGF-st...
Establishing an assay to evaluate d-amino acid oxidase enzyme kinetics and inhibition using WST-8 redox dye [0.03%]
利用WST-8氧化还原染料建立测定D型氨基酸氧化酶酶动力学和抑制作用的方法
Kahoko Miyake,Yuki Enoki,Yuka Nakazawa et al.
Kahoko Miyake et al.
d-Amino acid oxidase (DAO) inhibitors are novel candidate therapeutic agents for neurodegenerative diseases. In this study, a novel inhibition assay using WST-8 as a detection reagent was developed and its effectiveness for evaluating redox...
Single-molecule DNA flow-stretch assays for high-throughput DNA-protein interaction studies [0.03%]
单分子DNA流动拉伸测定技术在高通量DNA-蛋白质相互作用研究中的应用
Ayush Kumar Ganguli,Mohammad Nour Alsamsam,Ugnė Bagdonaitė et al.
Ayush Kumar Ganguli et al.
DNA-interacting proteins are involved in various molecular processes that are fundamental to cells' health and function. These include essential processes such as replication, DNA damage repair and transcriptional regulation. Additionally, ...
PARP inhibitors induce a senescence phenotype in non-small cell lung carcinoma cell lines [0.03%]
PARP抑制剂可在非小细胞肺癌细胞系中诱导衰老表型
Camille Huart,Manon Van den Abbeel,Christoph Schifflers et al.
Camille Huart et al.
Several anticancer treatments have been shown to activate the DNA damage repair pathway but also, in some cases, to lead to therapy-induced senescence. Senescent cells can either exert protumoral or antitumoral effects. However, it remains ...
Chameleon sequences reveal structural effects in proteins representing micelle-like distribution of hydrophobicity [0.03%]
变色龙序列揭示蛋白质中类似胶束的疏水分布效应
Irena Roterman,Katarzyna Stapor,Leszek Konieczny et al.
Irena Roterman et al.
The fundamental principle for protein structuring is that the 3D structure is determined by the amino acid sequence. An important phenomenon in this regard is the presence of a differentiated secondary structure for chain fragments of ident...
Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer [0.03%]
ERα外显子7拼接与乳腺癌 Luminal A型临床预后不良及表型异质性增加有关
Long Wai Tsui,Taobo Hu,Thomson Christian Husein et al.
Long Wai Tsui et al.
ERαΔ7 is one of the most frequently observed splice variants of the ESR1 gene in breast cancer but its functions remain largely unknown. Here we report that ERαΔ7 predicted poor survival in luminal A type breast cancer from TCGA data. E...
Applicability of mitotic figure counting by deep learning: a development and pan-cancer validation study [0.03%]
基于深度学习的有丝分裂计数的应用性：一项开发和泛癌验证研究
Joakim Kalsnes,Maria X Isaksen,Frida Julbø et al.
Joakim Kalsnes et al.
Mitotic figure counting is an established measure of cell proliferation that is included in grading systems. We developed a deep learning method for mitotic figure counting and evaluated its prognostic impact in multiple external validation...