Does miR-199a-3p Regulate Stearoyl-CoA Desaturase 1 (SCD1) in Ovine Tissues or Subcutaneous Adipocytes? Evidence for Species-Specific Differences [0.03%]
miR-199a-3p是否通过调节硬脂酰辅酶A脱氢酶1(SCD1)在羊组织或皮下脂肪细胞中发挥作用？物种间差异的证据
Aliute N S Udoka,Susan K Duckett
Aliute N S Udoka
Introduction: Stearoyl-CoA desaturase 1 (SCD1) is a key enzyme in the conversion of saturated (SFA) to monounsaturated fatty acids (MUFA) that alters the fatty acid composition of adipose tissues. We hypothesize that miR-...
miR-139 is a Tumor Suppressor microRNA with a Guanine-rich Precursor Terminal Loop [0.03%]
一种具有鸟嘌呤丰富前体末端环的肿瘤抑制microRNA-miR-139
Amit Cohen,Mario Alberto Burgos-Aceves,Yoav Smith
Amit Cohen
Introduction/objective: MicroRNAs (miRNAs) are key post-transcriptional regulators of gene expression that modulate cancer-related processes, including cell growth, proliferation, differentiation, and invasion. While nume...
Assessment of Correlation of miRNA-21 with Overall Survival in Patients with Oral Squamous Cell Carcinoma: An Observational Study [0.03%]
miRNA-21在口腔鳞状细胞癌患者中的总生存率相关性评估：一项观察性研究
Kiran B Jadhav,Nidhi Jadhav,Vandana Shah et al.
Kiran B Jadhav et al.
Introduction: Cervical lymph node metastasis is a well-established determinant of reduced overall survival in patients with Oral Squamous Cell Carcinoma (OSCC). MicroRNA-21 (miR-21), a key oncogenic regulator, has been im...
LncRNAs at the Crossroads of Breast Cancer Metastasis: Emerging Mechanisms and Therapeutic Prospects [0.03%]
长链非编码RNA在乳腺癌转移的十字路口：新兴机制和治疗前景
Arnab Dey,Kuppa Sree Vagdevi,Mohini Singh
Arnab Dey
Breast cancer metastasis is one of the leading causes of cancer-related mortality in women, which occurs through an intricate molecular network and cellular events. Over time, lncRNAs have emerged as an important regulator of metastatic pro...
Do Circulating miRNAs Exhibit Distinct Patterns in Coronary Artery Disease Patients? [0.03%]
冠心病患者中循环miRNA的表达模式分析
Chitra M Mestry,Minal U Paradkar,Nitin Shukla et al.
Chitra M Mestry et al.
Introduction: Coronary artery disease (CAD) remains a leading cause of morbidity and mortality worldwide. Identifying reliable biomarkers for early diagnosis and understanding the underlying molecular mechanisms are criti...
The miR-195-3p is a Novel Prognostic Biomarker, Inhibiting Angiogenesis in Lung Adenocarcinoma [0.03%]
miR-195-3p是肺腺癌预后新型生物标志物并抑制其血管生成作用
Wei Zhou,Dafa Zhang,Jun Nie
Wei Zhou
Introduction: In different kinds of tumors, miR-195-3p showed converse roles. How-ever, the role of miR-195-3p in lung adenocarcinoma (LUAD) remains unclear. To explore the prognostic role and potential underlying mechani...
Alberto Izzotti
Alberto Izzotti
Decoding TLR2 and BAX Gene Interactions on Maternal Immune Response in Frequent Spontaneous Abortions as Potential Biomarkers [0.03%]
Toll受体2和BAX基因在反复自然流产孕妇中的相互作用及作为潜在生物标志物的可能性
Kosar Babaei,Hossein Mozdarani,Misa Naghdipour Mirsadeghi et al.
Kosar Babaei et al.
Objective: Recurrent spontaneous abortion (RSA) represents a significant reproductive health challenge. The intricate balance of immune regulation at the maternal-fetal interface is crucial for maintaining pregnancy, invo...
The miR-29 Family in Virus-Associated Cancers: Mechanisms, Biomarkers, and Therapeutic Opportunities [0.03%]
病毒相关癌症中的miR-29家族：机制、生物标志物和治疗机会
Mohammad Sediq Yousufzai,Bezhan Noori,Ramin Shahbahrami
Mohammad Sediq Yousufzai
The miR-29 family (miR-29a, miR-29b, and miR-29c) demonstrates context-depend-ent roles in cancers associated with oncogenic viruses (HPV, HBV/HCV, EBV, and HTLV-1), which collectively contribute to 15-20% of human malignancies. This compre...
Nanomedicine for Alzheimer's Disease: Diagnostic and Therapeutic Progress [0.03%]
阿尔茨海默病的纳米医学：诊断和治疗进展
Himani Pandey,Awaneet Kaur,Javed Khan et al.
Himani Pandey et al.
The complex nature of the pathophysiology and limited treatment options of AD make it a huge challenge in healthcare. The recent developments in nanotechnology have given fresh hope for diagnosing and treating AD, which could serve as a way...