Spatially resolved whole-transcriptomic profiling of EGFR-mutated lung adenocarcinomas stratified by PD-L1 expression [0.03%]
基于PD-L1表达量分层的EGFR突变肺腺癌全转录组空间分辨谱分析
Chenxi Yu,Chenxi Shi,Hao Zhou et al.
Chenxi Yu et al.
Purpose: High programmed death-ligand 1 (PD-L1) expression is associated with unfavorable clinical outcomes in epidermal growth factor receptor (EGFR)-mutated lung adenocarcinomas (LUAD) patients treated with tyrosine kin...
Hepatoid adenocarcinoma of the stomach and non-hepatoid alpha-fetoprotein-producing gastric cancer exhibit a high degree of molecular similarity [0.03%]
胃肝样腺癌和非肝样的甲胎蛋白阳性胃癌具有较高的分子相似性
Liqiao Chen,Xuesong Yang,Peiyu Zhu et al.
Liqiao Chen et al.
Background: There is currently no unified consensus on the diagnosis and treatment of hepatoid adenocarcinoma of the stomach (HAS) and non-hepatoid AFP-producing gastric cancer (AFPGC). This study aims to explore the mole...
Correction to: Raloxifene inhibits pancreatic adenocarcinoma growth by interfering with ERβ and IL-6/gp130/STAT3 signaling [0.03%]
correction to：raloxifene通过干扰erβ和il-6/gp130/stat3信号抑制胰腺癌生长
Ioannis Pozios,Nina N Seel,Nina A Hering et al.
Ioannis Pozios et al.
Published Erratum
Cellular oncology (Dordrecht, Netherlands). 2025 Dec 8. DOI:10.1007/s13402-025-01128-8 2025
A Tumor-homing nanoplatform for the co-delivery of triptolide and siRNA-A4B2 conspicuously overcomes peritoneum metastasis of ovarian cancer [0.03%]
三联索和siRNA-A4B2肿瘤靶向递送纳米平台协同治疗卵巢癌腹膜扩散转移
Chenhuan Ding,Chen Wang,Junfeng Guo et al.
Chenhuan Ding et al.
Background: Despite advances in ovarian cancer treatment, the tendency for cancer cells to metastasise to the peritoneum still results in poor prognosis. Studies have demonstrated that the integrin family plays a role in ...
Tumor-infiltrating lymphocyte expansion protocols for adoptive cell therapy in cancer [0.03%]
肿瘤浸润性淋巴细胞的适应性细胞治疗扩增方案癌症
Daniel Tovar Manzano,Nabil Subhi-Issa,Alejandro Pereiro-Rodríguez et al.
Daniel Tovar Manzano et al.
Elimination of docetaxel-induced senescence attenuates malignant progression in RB1-deficient CRPC [0.03%]
RB1缺失的CRPC中消除多西他赛诱导的衰老可减弱恶性进展
Huilan Su,Liqun Huang,Wenwen Xia et al.
Huilan Su et al.
PURPOSE RETINOBLASTOMA L: (RB1) mutations frequently emerge as late subclonal events in advanced prostate cancer (PCa), driving inevitable recurrence and therapy resistance. Therapy-induced senescence (TIS) could promote metastasis at a lat...
ST6GAL1-mediated sialylation inhibits the antitumor immune response in colorectal cancer [0.03%]
黏蛋白修饰酶ST6GAL1通过抑制抗肿瘤免疫反应促进结直肠癌发生发展
Yuanchao Shi,Zhihong Peng,Zhenzhong Pan et al.
Yuanchao Shi et al.
Purpose: Interferon gamma (IFNG) directly affects the antitumor immune response. ST6-β-galactoside α-2,6-sialyltransferase 1 (ST6GAL1) is also positively correlated with poor prognosis for colorectal cancer (CRC). we pe...
Unraveling the miR-144-3p/PUMA pathway: a novel regulator of FDX1-mediated cuproptosis in colorectal cancer [0.03%]
miR-144-3p/PUMA通路解谜：FDX1介导的铜死亡在结直肠癌中的新调节机制
Guiyun Jia,Jiehan Li,Meimei Jiang et al.
Guiyun Jia et al.
Tumoral ALOX5 mediated arachidonic acid metabolism regulates immune response in non-small cell lung cancer [0.03%]
肿瘤性Alox5介导的花生四烯酸代谢调节非小细胞肺癌中的免疫反应
Yuan Gao,Yangchen Xia,Jiayao Li et al.
Yuan Gao et al.
Purpose: Tumor cells reprogram their fatty acid metabolism to meet the demands for their rapid proliferation. However, the interplay between fatty acid metabolism and the tumor microenvironment (TME) in lung cancer remain...
Long non-coding RNA in hepatocellular carcinoma: mechanistic insights and therapeutic perspectives [0.03%]
肝细胞癌中的长链非编码RNA：机制研究与治疗前景
Kexin Yu,Yuanxiang Jin,Yidong Zhou et al.
Kexin Yu et al.
Hepatocellular carcinoma (HCC) remains one of the most lethal malignancies worldwide, with its pathogenesis involving complex biological processes such as DNA damage, epigenetic modification and oncogene mutation. Over the past two decades,...