BRCA1 and RAD51C promotor methylation in human resectable pancreatic adenocarcinoma [0.03%]
人胰腺导管腺癌中BRCA1和RAD51C启动子的甲基化状况
Raëf Abdallah,Shulin Zhao,Simon Garinet et al.
Raëf Abdallah et al.
Background: Homozygous Recombination Deficiency (HRD) is associated with sensitivity to PARP-inhibitors (PARPi) in different cancer types. In pancreatic adenocarcinoma (PA) the main cause of HRD is BRCA1/2 germline mutati...
The effectiveness of radiofrequency ablation for patients with BCLC B1 stage hepatocellular carcinoma downgraded by transarterial chemoembolization [0.03%]
经导管动脉化疗栓塞后降级的巴塞罗那肝癌B1期患者射频消融疗效分析
Lu Li,Yujing Xin,Xinyuan Zhang et al.
Lu Li et al.
Purpose: To evaluate the effectiveness of radiofrequency ablation (RFA) as a curative therapy for BCLC B1 stage (beyond Milan criteria but within up-to-seven criteria) hepatocellular carcinoma (HCC) followed by downstagei...
Liver hypodense infectious lesions: Is it only bacteria, parasites or fungi? [0.03%]
肝脏低密度感染性病变：仅限于细菌、寄生虫或真菌吗？
E Hoornaert,J C Yombi,L Coubeau et al.
E Hoornaert et al.
Validation of EncephalApp_Stroop as screening tool for the detection of minimal hepatic encephalopathy in German patients with liver cirrhosis [0.03%]
验证EncephalApp_Stroop作为检测德国肝硬化患者轻微肝性脑病筛查工具的有效性
Leonard Kaps,Katharina Hildebrand,Michael Nagel et al.
Leonard Kaps et al.
Background: In contrast to overt hepatic encephalopathy (OHE), the diagnosis of minimal HE (MHE) is challenging in patients with cirrhosis requiring elaborate, specialized testing. The EncephalApp_Stroop is a smartphone-b...
Best practice guidelines for France regarding the diagnosis and management of autoimmune hepatitis [0.03%]
法国自身免疫性肝炎诊断和治疗指南
Jean-Charles Duclos-Vallée,Dominique Debray,Eleonora De Martin et al.
Jean-Charles Duclos-Vallée et al.
Transarterial chemoembolization (TACE) plus apatinib-combined therapy versus TACE alone in the treatment of intermediate to advanced hepatocellular carcinoma patients: A real-world study [0.03%]
经导管动脉化疗栓塞(TACE)联合阿帕替尼治疗中晚期肝细胞癌患者的疗效观察：真实世界研究
Hui Wang,Donghui Liu,Chu Wang et al.
Hui Wang et al.
Background: Apatinib exhibits the synergistic effect with transarterial chemoembolization (TACE) though inhibiting the neoangiogenetic reaction caused by TACE. In this real-world study, we aimed to evaluate the efficacy a...
Long non-coding RNA plasmacytoma variant translocation 1 correlates with higher inflammation, multiple organ injury and mortality risk in acute pancreatitis, especially in severe acute pancreatitis [0.03%]
长非编码RNA浆细胞样B细胞变异转移基因1与急性胰腺炎炎症、多器官功能障碍和死亡风险相关，尤其是在重症急性胰腺炎中相关性更强
Xue Liu,Ye Lin
Xue Liu
Background: Long non-coding RNA plasmacytoma variant translocation 1 (lnc-PVT1) possesses a good ability to regulate inflammation as well as multiple organ injury via multiple pathways, and clinically exacerbates severe a...
Comparison of cold biopsy forceps vs cold snare for diminutive colorectal polyp removal: A multicenter non-inferiority randomized controlled trial [0.03%]
冷活检钳与冷圈套器切除微小结肠息肉的非劣效性多中心随机对照试验
Guillaume Perrod,Enrique Perez-Cuadrado-Robles,Emmanuel Coron et al.
Guillaume Perrod et al.
Background: European guidelines recommends the use of cold snare polypectomy (CSP) for removal of diminutive colorectal polyps (DCP). However, for DCP < 4 mm cold biopsy forceps (CBF) may be optional. We aimed to compare ...
Randomized Controlled Trial
Clinics and research in hepatology and gastroenterology. 2022 Mar;46(3):101867. DOI:10.1016/j.clinre.2022.101867 2022
Thomas Bardol,Charlotte Ferrandis,Regis Souche
Thomas Bardol
Paragangliomas are extra-adrenal pheochromocytomas that arise from chromaffin cells in the sympathetic or parasympathetic neural paraganglia. Surgery remains the only curative treatment, although prominent vascularity can make excision diff...
Paul Wasuwanich,Joshua M So,Ann O Scheimann et al.
Paul Wasuwanich et al.
Background: Hydrothorax in the presence of ascites is a serious condition, but it is not well studied, particularly in pediatrics. We aim to identify risk factors for having hydrothorax, compare morbidity and mortality, a...