BRCA1 and RAD51C promotor methylation in human resectable pancreatic adenocarcinoma
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Background: Homozygous Recombination Deficiency (HRD) is associated with sensitivity to PARP-inhibitors (PARPi) in different cancer types. In pancreatic adenocarcinoma (PA) the main cause of HRD is BRCA1/2 germline mutation and p... ...
