Novel IgG-IgM Autoantibody Panel Enhances Detection of Early-stage Lung Adenocarcinoma from Benign Nodules [0.03%]
新型的IgG-IgM自身抗体谱系能够增强早期肺腺癌与良性结节的鉴别诊断能力
Rongrong Luo,Xiying Li,Ruyun Gao et al.
Rongrong Luo et al.
Autoantibodies hold promise for diagnosing lung cancer. However, their effectiveness in early-stage detection needs improvement. We investigated novel IgG and IgM autoantibodies for detection of early-stage lung adenocarcinoma (Early-LUAD) ...
iMFP-LG: Identification of Novel Multi-Functional Peptides by Using Protein Language Models and Graph-Based Deep Learning [0.03%]
基于蛋白质语言模型和图深度学习的新型多功能肽识别(iMFP-LG)
Jiawei Luo,Kejuan Zhao,Junjie Chen et al.
Jiawei Luo et al.
Functional peptides are short amino acid fragments that have a wide range of beneficial functions for living organisms. The majority of previous research focused on mono-functional peptides, but a growing number of multi-functional peptides...
ProtPipe: A Multifunctional Data Analysis Pipeline for Proteomics and Peptidomics [0.03%]
ProtPipe：一种用于蛋白质组学和肽组学的多功能数据分析流程管道
Ziyi Li,Cory A Weller,Syed Shah et al.
Ziyi Li et al.
Mass spectrometry (MS) is a technique widely employed for the identification and characterization of proteins, with personalized medicine, systems biology, and biomedical applications. The application of MS-based proteomics advances our und...
Tao Zhang,Yiyun Liu,Xutong Guo et al.
Tao Zhang et al.
The rapid expansion of the number of viral genome sequences in public databases necessitates a scalable, universal, and automated preliminary taxonomic framework for comprehensive virus studies. Here, we introduce VISTA (Virus Sequence-base...
Pangenome Reveals Gene Content Variations and Structural Variants Contributing to Pig Characteristics [0.03%]
泛基因组揭示影响猪特征的基因内容变异和结构变异
Heng Du,Yue Zhuo,Shiyu Lu et al.
Heng Du et al.
Pigs are among the most essential sources of high-quality protein in human diets. Structural variants (SVs) are a major source of genetic variants associated with diverse traits and evolutionary events. However, the current linear reference...
SoyOD: An Integrated Soybean Multi-omics Database for Mining Genes and Biological Research [0.03%]
大豆OD综合数据库：挖掘基因和生物研究的集成大豆多组学数据库
Jie Li,Qingyang Ni,Guangqi He et al.
Jie Li et al.
Soybean is a globally important crop for food, feed, oil, and nitrogen fixation. A variety of multi-omics studies has been carried out, generating datasets ranging from genotype to phenotype. In order to efficiently utilize these data for b...
Bing He,Wanfei Liu,Jianyang Li et al.
Bing He et al.
The rapid development of sequencing technology has led to an explosion of plant genome data, opening up more opportunities for research in the field of comparative evolutionary analysis of plant genomes. In this review, we focus on changes ...
Enzymes Repertoires and Genomic Insights into Lycium Barbarum Pectin Polysaccharides Biosynthesis [0.03%]
枸杞果胶多糖生物合成的酶学和基因组学研究进展
Haiyan Yue,Yiheng Tang,Aixuan Li et al.
Haiyan Yue et al.
Lycium barbarum, a member of the Solanaceae family, represents an important eudicot lineage with homology of food and medicine. Lycium barbarum pectin polysaccharides (LBPPs) are key bioactive ingredients of Lycium barbarum, and are among t...
Multiome-wide Association Studies: Novel Approaches for Understanding Diseases [0.03%]
多组学关联研究：理解疾病的新方法
Mengting Shao,Kaiyang Chen,Shuting Zhang et al.
Mengting Shao et al.
The rapid development of multiome (transcriptome, proteome, cistrome, imaging, and regulome)-wide association study methods have opened new avenues for biologists to understand the susceptibility genes underlying complex diseases. Thorough ...
Comprehensive Characterization of the Integrin Family Across 32 Cancer Types [0.03%]
整合素家族在32种癌症类型中的全面特征分析
Cheng Zou,Jinwei Zhu,Jiangling Xiong et al.
Cheng Zou et al.
Integrin genes are widely involved in tumorigenesis. Yet, a comprehensive characterization of integrin family members and their interactome at the pan-cancer level is lacking. Here, we systematically analyzed integrin family in approximatel...