Advanced Detection of Pancreatic Cancer Circulating Tumor Cells Using Biomarkers and Magnetic Particle Spectroscopy [0.03%]
基于生物标志物和磁性纳米粒子频谱法的胰腺癌循环肿瘤细胞检测技术
Ali Dinari,Hafiz Ashfaq Ahmad,Seungjun Oh et al.
Ali Dinari et al.
Background: Pancreatic ductal adenocarcinoma (PDAC) typically develops without symptoms, and its aggressive progression combined with late-stage diagnosis underscores the critical need for improved early detection strategies. Circulating tu...
Microemulsion Gels of Tapentadol Hydrochloride: Statistical Analysis of Pharmacokinetics and Skin Irritation Studies [0.03%]
盐酸泰普森多微乳凝胶：药代动力学和皮肤刺激研究的统计分析
Nimmathota Madhavi,Naveen Kumar Ganji,Heera Battu et al.
Nimmathota Madhavi et al.
Background: The present study aimed to overcome the drawbacks of tapentadol through the oral route and to assess the significance of microemulsion gels for transdermal delivery via pharmacokinetic approach. Methods: Microemulsions were prep...
Swarnima Pandey
Swarnima Pandey
With the apparent rise in lifestyle-related changes, there has been a significant decline in renal health. Metabolomics plays a crucial role in the prognosis, diagnosis, and treatment of various renal conditions, including chronic kidney di...
GMP manufacturing of umbilical cord blood mesenchymal stem cell-released exosomes and verification of wound healing efficacy [0.03%]
胎盘间充质干细胞外泌体的GMP生产及其促进伤口愈合功效验证的研究
Jae-Yong Lee,Jaehyoung Kim,Kyuheum Na et al.
Jae-Yong Lee et al.
Rationale: Drug development research using exosomes is being actively conducted worldwide. However, clear management standards and verification systems for the use of exosomes as drugs are still being developed. In this study, the effective...
A miniature low-immunogenic platform for the biosynthesis of self-assembling protein nanoparticles [0.03%]
用于自组装蛋白纳米颗粒生物合成的微型低免疫原性平台
Almina I Polinova,Anna V Serkina,Marina V Volkova et al.
Almina I Polinova et al.
Aims: Previously, to obtain antigen-presenting self-assembling protein nanoparticles (SAPN), we developed a biosynthetic platform combining the self-associating peptide L6KD and the SUMO protein. In the current work, the immunogenic SUMO wa...
Pranjal Chandra
Pranjal Chandra
A growing need for rapid disease detection worldwide highlights the importance of innovative approaches to ensure prompt diagnosis and more effective patient care. As of now, various nanobioengineered systems have been developed and applied...
Dual Potential of Cetuximab Conjugated Hydroxyapatite Zirconium Nanoparticle as Nanocarrier for Radioenhancer in X-Ray Dynamic Therapy and 177Lu-based Radioimmunotherapy of Lung Cancer [0.03%]
cetuximab连接的羟基磷灰石锆纳米颗粒作为X射线动态治疗放射增敏剂纳米载体及肺癌177卢基于放射免疫治疗的双重潜能
Ahmad Kurniawan,Isa Mahendra,Asep Rizaludin et al.
Ahmad Kurniawan et al.
This study aimed to synthesize cetuximab (CTX) conjugated hydroxyapatite zirconium (HApZr-CTX) as a nanocarrier for active delivery of photosensitizer and therapeutic radionuclide. The system enabled targeted radioenhancer in X-ray dynamic ...
Structural Dynamics of OATP1A2 in Mediating Paclitaxel Transport Mechanism in Breast Cancer [0.03%]
OATP1A2在乳腺癌紫杉醇转运机制中的结构动力学研究
Rohit Kumar,Garima Singh,Yusuf Akhter et al.
Rohit Kumar et al.
Breast cancer remains a significant global health challenge, with drug resistance and poor bioavailability of chemotherapeutic agents like paclitaxel (PTX) presenting obstacles to effective treatment. This study investigates the potential r...
Preparation and Characterization of Carbon Nanodots from turmeric soot for anti-coliform and anti-oral bacterial applications and as anti-staphylococcal coatings [0.03%]
从姜黄烟灰中制备和表征碳量子点用于抗大肠菌群和抗口腔细菌的应用及作为抗金黄色葡萄球菌的涂层研究
Arjun Prakash,Manikandan Muthu,Gnanadeepam Raja et al.
Arjun Prakash et al.
In an era where chemical synthesis of nanomaterial is accounting for the generation of toxic wastes, leading to nanotoxicity, the present work focuses on the extraction of carbon nanodots from available natural sources such as turmeric smok...
Development and assessment of a novel magnetic nanoparticle antibody-conjugate and aptamer-based assay (MNp-Ab-Ap assay) for the rapid diagnosis of pleural tuberculosis [0.03%]
用于快速诊断胸膜结核的新型磁性纳米颗粒抗体-缀合物和适配子测定法(MNp-Ab-Ap测定法)的发展与评估
Pratibha Sharma,Rakesh Kumar Gupta,Simran Aittan et al.
Pratibha Sharma et al.
Background: Pleural tuberculosis (pTB) is a diagnostic challenge because of its non-specific clinical features, lack of accurate diagnostic tools and paucibacillary nature of the disease. Methods: We, here describe the development of a nove...