Bacterial magnetosomes loaded with doxorubicin and transferrin improve targeted therapy of hepatocellular carcinoma [0.03%]
载有阿霉素和转铁蛋白的细菌磁小体改善肝细胞癌靶向治疗
Jiaojiao Wang,Yuanyuan Geng,Yunpeng Zhang et al.
Jiaojiao Wang et al.
High metastatic rate and recurrence of tumor because of tumor circulating cells are seriously hinders for clinical tumor therapy. Herein, we develop a novel, active-targeting nanotherapeutic by simultaneously loading doxorubicin (DOX) and t...
Polydopamine-coated gold nanostar for combined antitumor and antiangiogenic therapy in multidrug-resistant breast cancer [0.03%]
包被聚多巴胺的金纳米星用于耐多药乳腺癌的联合抗肿瘤和抗血管生成治疗
You-Hong You,Yu-Feng Lin,Bhanu Nirosha et al.
You-Hong You et al.
Cancer combination therapy can improve treatment efficacy and is widely utilized in the biomedical field. In this paper, we propose a facile strategy to develop a polydopamine (PDA)-coated Au nanostar (NS@PPFA) as a multifunctional nanoplat...
68Ga-Sienna+ for PET-MRI Guided Sentinel Lymph Node Biopsy: Synthesis and Preclinical Evaluation in a Metastatic Breast Cancer Model [0.03%]
68镓-西奈娜+用于PET-MRI引导的前哨淋巴结活检：合成及乳腺癌转移小鼠模型中的前临床评价
Heli Savolainen,Alessia Volpe,Alkystis Phinikaridou et al.
Heli Savolainen et al.
Sentinel lymph node biopsy (SLNB) is commonly performed in cancers that metastasise via the lymphatic system. It involves excision and histology of sentinel lymph nodes (SLNs) and presents two main challenges: (i) sensitive whole-body local...
Co-precipitation Synthesis of Near-infrared Iron Oxide Nanocrystals on Magnetically Targeted Imaging and Photothermal Cancer Therapy via Photoablative Protein Denature [0.03%]
近红外铁氧化物纳米结晶的共沉淀合成，以磁 targeting 成像和光热癌症疗法通过光消融蛋白变性
Wei-Jhe Syu,Chih-Chia Huang,Jong-Kai Hsiao et al.
Wei-Jhe Syu et al.
Near-infrared (NIR)-based nanomaterials that provide efficient tumor ablation for cancer therapy have been reported. However, the issues of biocompatibility of metals or ions in inorganic nanoparticles systems such as copper and gold nanopa...
Overcoming hypoxia-induced chemoresistance to cisplatin through tumor oxygenation monitored by optical imaging [0.03%]
通过光学成像监测肿瘤氧合来克服顺铂诱导的低氧抗药性
Donghui Song,André O&#x;Reilly Beringhs,Zhenwu Zhuang et al.
Donghui Song et al.
Perfluorocarbon nanoparticles have been reported to deliver oxygen to tumors and reduce hypoxia-induced radioresistance, however few studies have been carried out to study its role in reducing hypoxia-induced chemoresistance. The oxygenatio...
Ultrasound-mediated delivery of siESE complexed with microbubbles attenuates HER2+/- cell line proliferation and tumor growth in rodent models of breast cancer [0.03%]
基于微泡的siESE复合物超声介导递送抑制乳腺癌细胞系增殖及肿瘤生长
Kang-Ho Song,Tammy Trudeau,Adwitiya Kar et al.
Kang-Ho Song et al.
The highly tunable, noninvasive and spatially targeted nature of microbubble-enhanced, ultrasound-guided (MB+US) drug delivery makes it desirable for a wide variety of therapies. In breast cancer, both HER2+ and HER2- type neoplasms pose si...
Derek Reichel,Manisha Tripathi,Pramod Butte et al.
Derek Reichel et al.
Purpose: A successful cancer surgery requires the complete removal of cancerous tissue, while also sparing as much healthy, non-cancerous tissue as possible. To achieve this, an accurate identification of tumor boundaries during surgery is ...
Various Nucleolar Stress Inducers Result in Highly Distinct Changes in Water, Dry Mass and Elemental Content in Cancerous Cell Compartments: Investigation Using a Nano-Analytical Approach [0.03%]
核糖体应激诱导剂导致癌症细胞组分中水、干质量和元素含量的高度不同的变化：使用纳米分析方法进行研究
Jean Michel,Frédérique Nolin,Laurence Wortham et al.
Jean Michel et al.
Rationale: Numerous chemotherapeutic drugs that affect ribosome biogenesis in the nucleolus induce nucleolar stress. Improving our understanding of the effects of these drugs will require uncovering and comparing their impact on several bio...
Magnetic Heating Stimulated Cargo Release with Dose Control using Multifunctional MR and Thermosensitive Liposome [0.03%]
具有剂量控制的多模式MR和热敏脂质体磁加热刺激载药释放
Sayoni Ray,Chi-An Cheng,Wei Chen et al.
Sayoni Ray et al.
Rationale: Magnetic resonance imaging (MRI) is one of the most widely used diagnostic tools in the clinic. In this setting, real-time monitoring of therapy and tumor site would give the clinicians a handle to observe therapeutic response an...
Near-Infrared Organic Fluorescent Nanoparticles for Long-term Monitoring and Photodynamic Therapy of Cancer [0.03%]
用于长期监测和光动力治疗的近红外有机荧光纳米粒子
Qi Xia,Zikang Chen,Yuping Zhou et al.
Qi Xia et al.
Photodynamic therapy (PDT), which utilizes reactive oxygen species to ablate tumor, has attracted much attention in recent years. Photosensitizers with near-infrared (NIR) fluorescence as well as efficient ROS generation ability have been u...