Brain iron deposition after Ferumoxytol-enhanced MRI: A study of Porcine Brains [0.03%]
富铁氧体明胶增强MRI后脑铁沉积的猪脑研究
Ashok Joseph Theruvath,Maryam Aghighi,Michael Iv et al.
Ashok Joseph Theruvath et al.
Recent evidence of gadolinium deposition in the brain has raised safety concerns. Iron oxide nanoparticles are re-emerging as promising alternative MR contrast agents, because the iron core can be metabolized. However, long-term follow up s...
Targeted Molecular Iron Oxide Contrast Agents for Imaging Atherosclerotic Plaque [0.03%]
针对动脉粥样硬化斑块的分子级铁氧体对比剂影像代理砷製备技術
Rhiannon J Evans,Begoña Lavin,Alkystis Phinikaridou et al.
Rhiannon J Evans et al.
Overview: Cardiovascular disease remains a leading cause of death worldwide, with vulnerable plaque rupture the underlying cause of many heart attacks and strokes. Much research is focused on identifying an imaging biomarker to differentiat...
Biodistribution and acute toxicity of cadmium-free quantum dots with different surface functional groups in mice following intratracheal inhalation [0.03%]
无镉量子点在小鼠肺部的生物分布及急性毒性研究——不同表面修饰功能团的影响
Guimiao Lin,Ting Chen,Yongning Pan et al.
Guimiao Lin et al.
Indium phosphide/zinc sulfate (InP/ZnS) quantum dots (QDs) are presumed to be less hazardous than those that contain cadmium. However, the toxicological profile has not been established. The present study investigated the acute toxicity of ...
Supramolecular Polysaccharide Nanotheranostics that Inhibit Cancer Cells Growth and Monitor Targeted Therapy Response [0.03%]
一种抑制癌细胞生长并监测靶向治疗反应的超分子多糖纳米诊疗剂
Nilesh Deshpande,Anujan Ramesh,Dipika Nandi et al.
Nilesh Deshpande et al.
Targeted anticancer therapies directed against specific molecular drivers of tumors are emerging as effective treatment strategies, however, monitoring their response is still challenging. Current clinical imaging techniques that measure ei...
Preclinical evaluation of cationic DOTA-triarginine-lipid conjugates for theranostic liquid brachytherapy [0.03%]
阳离子DOTA-三精氨酸-脂质偶联物的治疗诊断液体近距离放射疗法的临床前评估研究
Wenbo Wang,Frederikke P Fliedner,Anders E Hansen et al.
Wenbo Wang et al.
Liquid brachytherapy is an emerging technology for internal radiation therapy where liquids containing radionuclides are administered directly into solid tumors. These technologies are less invasive than conventional brachytherapy, and can ...
Multicolor spectral photon counting CT monitors and quantifies therapeutic cells and their encapsulating scaffold in a model of brain damage [0.03%]
多色光子计数CT监测和量化治疗细胞及其封装支架在脑损伤模型中的作用
Elisa Cuccione,Peter Chhour,Salim Si-Mohamed et al.
Elisa Cuccione et al.
Rationale & aim: Various types of cell therapies are currently under investigation for the treatment of ischemic stroke patients. To bridge the gap between cell administration and therapeutic outcome, there is a need for non-invasive monito...
Establishment of a hTfR mAb-functionalized HPPS theranostic nanoplatform [0.03%]
基于hTfR单克隆抗体的功能化HPPS治疗诊断一体化纳米平台的构建
Qi He,Zilong Guo,Mingpeng Fu et al.
Qi He et al.
Rational: Many efforts have been made to develop ligand-directed nanotheranostics in cancer management which could afford both therapeutic and diagnostic functions as well as tumor-tailored targeting. Theranostic nanoplatform targeting tran...
Binding of Targeted Semiconducting Photothermal Polymer Nanoparticles for Intraperitoneal Detection and Treatment of Colorectal Cancer [0.03%]
用于腹腔内结直肠癌检测和治疗的靶向半导体光热聚合物纳米粒子绑定技术
Eleanor McCabe-Lankford,Bryce McCarthy,Margarita Arakelyan-Peters Berwick et al.
Eleanor McCabe-Lankford et al.
Nanoparticles offer many promising advantages for improving current surgical regimens through their ability to detect and treat disseminated colorectal cancer (CRC). Hybrid Donor-Acceptor Polymer Particles (HDAPPs) have recently been shown ...
Liposome-Templated Indocyanine Green J- Aggregates for In Vivo Near-Infrared Imaging and Stable Photothermal Heating [0.03%]
用于活体近红外成像和稳定光热加热的脂质体制备吲哚青绿J型聚集体系
Calvin C L Cheung,Guanglong Ma,Kostas Karatasos et al.
Calvin C L Cheung et al.
Indocyanine green (ICG) is an FDA-approved near-infrared fluorescent dye that has been used in optical imaging and photothermal therapy. Its rapid in vivo clearance and photo-degradation have limited its application. ICG pharmacokinetics an...
Traci D Reusser,Kang-Ho Song,David Ramirez et al.
Traci D Reusser et al.
In recent work, oxygen microbubbles (OMB) have been shown to oxygenate hypoxic tumors, increase radio-sensitivity and improve tumor control by radiation therapy. Compared to intra-tumoral injection, intravenous delivery of adjuvant agents s...