Cyclodextrin nanosponge for the GSH-mediated delivery of Resveratrol in human cancer cells [0.03%]
用于人类癌细胞中的GSH介导的白藜芦醇传递的环糊精纳米海绵
Marco Palminteri,Nilesh Kumar Dhakar,Alessandra Ferraresi et al.
Marco Palminteri et al.
Smart drug delivery systems are required for the site-specific drug targeting to enhance the therapeutic efficiency of a drug. Resveratrol (RV) is a polyphenolic compound with anti-cancer activity. However, its poor aqueous solubility and n...
Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors [0.03%]
PSMA靶向光动力疗法可增强PSMA靶向磁性纳米颗粒向前列腺肿瘤的传递
Ethel J Ngen,Ying Chen,Babak Behnam Azad et al.
Ethel J Ngen et al.
Enhanced vascular permeability in tumors plays an essential role in nanoparticle delivery. Prostate-specific membrane antigen (PSMA) is overexpressed on the epithelium of aggressive prostate cancers (PCs). Here, we evaluated the feasibility...
Non-invasive multimodal imaging of Diabetic Retinopathy: A survey on treatment methods and Nanotheranostics [0.03%]
糖尿病视网膜病变的非侵入性多模态影像学：治疗手段及纳米诊疗体系综述
Rajkumar Sadasivam,Gopinath Packirisamy,Snehlata Shakya et al.
Rajkumar Sadasivam et al.
Diabetes Retinopathy (DR) is one of the most prominent microvascular complications of diabetes. It is one of the pre-eminent causes for vision impairment followed by blindness among the working-age population worldwide. The de facto cause f...
Strategies for the functionalisation of gold nanorods to reduce toxicity and aid clinical translation [0.03%]
减少金纳米棒毒性的功能化策略及其临床转化促进方法
Xin Shi,Hannah L Perry,James D E T Wilton-Ely
Xin Shi
Gold nanorods (GNRs) show great promise as photothermal therapy agents due to their remarkable ability to convert light into heat. In most cases, gold nanorods are synthesised via a seed-mediated method assisted by surfactants. However, the...
Resveratrol and its Nanoparticle suppress Doxorubicin/Docetaxel-resistant anaplastic Thyroid Cancer Cells in vitro and in vivo [0.03%]
白藜芦醇及其纳米颗粒通过体内和体外实验抑制多药耐药性未分化甲状腺癌细胞生长
Le Xiong,Xiao-Min Lin,Jun-Hua Nie et al.
Le Xiong et al.
Background: Docetaxel and doxorubicin combination has been widely used in anaplastic thyroid cancer/ATC treatment but often results in serious adverse effects and drug resistance. Resveratrol effectively inhibits ATC cell proliferation in v...
MR-labelled liposomes and focused ultrasound for spatiotemporally controlled drug release in triple negative breast cancers in mice [0.03%]
磁共振标记的脂质体和聚焦超声在携带三阴性乳腺癌的小鼠中时空可控释放药物中的应用研究
Maral Amrahli,Miguel Centelles,Paul Cressey et al.
Maral Amrahli et al.
Rationale: Image-guided, triggerable, drug delivery systems allow for precisely placed and highly localised anti-cancer treatment. They contain labels for spatial mapping and tissue uptake tracking, providing key location and timing informa...
Resveratrol loaded polymeric micelles for theranostic targeting of breast cancer cells [0.03%]
用于乳腺癌细胞诊疗的白藜芦醇载药聚合物胶束
Yiota Gregoriou,Gregoria Gregoriou,Vural Yilmaz et al.
Yiota Gregoriou et al.
Treatment of breast cancer underwent extensive progress in recent years with molecularly targeted therapies. However, non-specific pharmaceutical approaches (chemotherapy) persist, inducing severe side-effects. Phytochemicals provide a prom...
Omar Abousaway,Taha Rakhshandehroo,Annick D Van den Abbeele et al.
Omar Abousaway et al.
Immunotherapy has revolutionized the treatment of several malignancies. Notwithstanding the encouraging results, many patients do not respond to treatments. Evaluation of the efficacy of treatments is challenging and robust methods to predi...
Qiao-Ru Guo,Ling-Ling Zhang,Ji-Fang Liu et al.
Qiao-Ru Guo et al.
Microfluidic chip is not a chip in the traditional sense. It is technologies that control fluids at the micro level. As a burgeoning biochip, microfluidic chips integrate multiple disciplines, including physiology, pathology, cell biology, ...
Intraoperative assessment and postsurgical treatment of prostate cancer tumors using tumor-targeted nanoprobes [0.03%]
利用肿瘤靶向纳米探针进行前列腺癌手术中的评估和术后的治疗
James Teh,Manisha Tripathi,Derek Reichel et al.
James Teh et al.
Successful visualization of prostate cancer (PCa) tumor margins during surgery remains a major challenge. The visualization of these tumors during surgery via near infrared fluorescence (NIRF) imaging would greatly enhance surgical resectio...