Synovial pH, lactate, and glucose as adjunct biomarkers to exclude periprosthetic joint infection in hip and knee arthroplasty: a prospective study [0.03%]
滑膜pH值、乳酸和葡萄糖作为辅助生物标志物排除髋关节和膝关节置换术后假体周围关节感染：一项前瞻性研究
Dirk Müller,Joshua Aulenbacher,Niels Heine et al.
Dirk Müller et al.
Background: Synovial pH, glucose, and lactate have been studied in native joint septic arthritis, but studies in periprosthetic joint infection (PJI) are limited. The purpose of this study is to evaluate the diagnostic utility of synovial p...
The burden of periprosthetic joint infections: patient-reported outcomes and qualitative insights into periprosthetic joint infections [0.03%]
人工关节感染的负担：患者报告的结果和人工关节感染的质性见解
Franz-Joseph Dally,Frido Kixmöller,Frederic Bludau et al.
Franz-Joseph Dally et al.
Introduction: Periprosthetic joint infections (PJIs) have a severe physical impact and impose a significant psychological burden. This study aimed to compare patient-reported outcome measures (PROMs) and qualitative interview data within th...
Inadequate empirical antibiotics following debridement for orthopedic infections do not increase therapy failures [0.03%]
骨科感染清创术后经验性使用抗生素不足不会增加治疗失败率
Steven Mark Maurer,Marc Simon Maurer,Marc Schmid et al.
Steven Mark Maurer et al.
Introduction: Empirical antibiotics should only target the most likely pathogens if antibiotic stewardship is being heeded. However, there is a drive for broader-spectrum empirical antibiotics in orthopedic infections due to the concern of ...
Proteus-species-associated periprosthetic hip and knee joint infections - a 15-year cohort analysis [0.03%]
类蛋白假单胞菌与关节周围假体感染——一项为期15年的队列分析研究
Veronika Achatz,Jennyfer A Mitterer,Stephanie Huber et al.
Veronika Achatz et al.
Introduction: While Gram-negative periprosthetic joint infections (PJIs) are generally known for their poor outcome, few data on Proteus species exist. Therefore, we investigated the prevalence, clinical characteristics, microbial spectrum,...
Proactive Therapeutic Drug MONiToring to Guide Suppressive Antibiotic Therapy with DALBAvaNcin ( > 12 weeks) in Osteoarticular Infections (MONTALBANO) [0.03%]
主动性的治疗药物监测指导 Dalbavancin 抑制性抗生素治疗（大于 12 周）治疗骨关节感染(MONTALBANO)研究
Chiara Mariani,Matteo Passerini,Lucia Galli et al.
Chiara Mariani et al.
Introduction: Long-term dalbavancin use is increasingly adopted off-label for osteoarticular infections (OAIs), but data on administration timing and long-term effects beyond 12 weeks are scarce. This study evaluated the pharmacological eff...
One-stage knee replacement shows similar healing rates in patients with negative or positive preoperative cultures: a retrospective cohort study [0.03%]
一期膝关节置换术患者术前培养阴性或阳性愈合率相似：回顾性队列研究
Marta Sabater-Martos,Laura Morata,Josep Maria Segur et al.
Marta Sabater-Martos et al.
Introduction: Treatment of chronic periprosthetic joint infections (PJIs) involves prosthesis removal, reimplantation, and antibiotic treatment. This process can be performed as a two-stage replacement or a one-stage replacement. One-stage ...
No difference in failure between static, articulating, and prosthetic low-friction spacers for periprosthetic joint infection of total knee arthroplasty [0.03%]
全膝关节置换术后假体周围感染采用静态、活动型和假体低摩擦 spacer 治疗失败率无差异
Michael F Shannon,Timothy Edwards,Timothy Maurer et al.
Michael F Shannon et al.
Introduction: Two-stage revision with an antibiotic spacer is the gold-standard treatment of prosthetic joint infection (PJI) for total knee arthroplasty (TKA). Multiple spacer designs exist, including static, articulated, and prosthetic lo...
Type of acute periprosthetic joint infection may not affect failure of debridement, antibiotics, and implant retention after total knee arthroplasty [0.03%]
急性人工关节感染类型可能不会影响全膝关节置换术后清创、抗菌药物和假体保留治疗的失败率
Andrew J Frear,Michael F Shannon,Shaan Sadhwani et al.
Andrew J Frear et al.
Introduction: In periprosthetic joint infection (PJI) following total knee arthroplasty (TKA), debridement, antibiotics, and implant retention (DAIR) is a common procedure with a high rate of failure. Timing of infection can be used to stra...
Risk factors for treatment failure in late acute periprosthetic joint infection in patients with rheumatoid arthritis treated with surgical debridement - a case-control study [0.03%]
接受外科清创术治疗的类风湿关节炎患者的晚期急性假体周围关节感染治疗失败的风险因素-一项病例对照研究
Hendrika M Schenk,Marine Sebillotte,Jose Lomas et al.
Hendrika M Schenk et al.
Background: Patients with rheumatoid arthritis (RA) with late acute periprosthetic joint infections (PJIs) treated with surgical debridement, antibiotics, and implant retention (DAIR) have a high failure rate. We conducted a case-control st...
The value of repeated debridement, antibiotics, and implant retention (DAIR) for early periprosthetic joint infection [0.03%]
反复清创、抗生素和假体保留(DAIR)治疗早期关节置换术后感染的价值
Ruben Scholten,Gerjon Hannink,Matthijs P Somford et al.
Ruben Scholten et al.
Background and purpose: Debridement, antibiotics, and implant retention (DAIR) is the proposed initial treatment of early periprosthetic joint infection (PJI), but it may fail to provide infection control. Subsequently, either implant remov...