Which Orthopaedic Patients Are Infected with Gram-negative Non-fermenting Rods? [0.03%]
哪些骨科病人感染非发酵革兰氏阴性杆菌？
Omid Jamei,Shpresa Gjoni,Besa Zenelaj et al.
Omid Jamei et al.
Background : 1st and 2nd generation cephalosporins used for perioperative prophylaxis in orthopaedic surgery do not cover non-fermenting Gram-negative rods (NFR). Methods: Epidemiological cohort study of adult patients operated for orthoped...
Hyaluronic Acid and Its Composites as a Local Antimicrobial/Antiadhesive Barrier [0.03%]
透明质酸及其复合物作为局部抗菌/抗黏附屏障
C L Romanò,E De Vecchi,M Bortolin et al.
C L Romanò et al.
Living in biofilms is probably the most common condition for bacteria and fungi and biofilm-related infections account for the majority of bacterial infectious diseases worldwide. Among others biofilm-related infections, those associated wi...
Heinz Winkler,Peter Haiden
Heinz Winkler
The treatment of chronic bone and joint infections is characterized by obstinate persistency of the causing microorganisms and resulting long term disability to patients, associated with remarkable costs for the health care system. Difficul...
Ceramic Biocomposites as Biodegradable Antibiotic Carriers in the Treatment of Bone Infections [0.03%]
陶瓷生物复合材料作为骨感染治疗中可降解的抗生素载体
Jamie Ferguson,Michael Diefenbeck,Martin McNally
Jamie Ferguson
Local release of antibiotic has advantages in the treatment of chronic osteomyelitis and infected fractures. The adequacy of surgical debridement is still key to successful clearance of infection but local antibiotic carriers seem to afford...
Therapeutic Use of Antibiotic-loaded Bone Cement in the Treatment of Hip and Knee Joint Infections [0.03%]
载药骨水泥在髋、膝关节感染治疗中应用的专家共识
Konstantinos Anagnostakos
Konstantinos Anagnostakos
The use of antibiotic-loaded cement spacers is an established method in the management of periprosthetic hip and knee joint infections. Despite inconsistencies among published studies, data shows that infection control rates exceed 90% with...
Local Intra-wound Administration of Powdered Antibiotics in Orthopaedic Surgery [0.03%]
骨科手术中伤口局部使用抗生素粉剂
Andrew N Fleischman,Matthew S Austin
Andrew N Fleischman
Surgical site infection (SSI) is one of the most common complications after orthopaedic surgery, leading to significant morbidity and its associated costs. Surgical guidelines strongly recommend the use of systemic antibiotic prophylaxis to...
Jaiben George,Alison K Klika,Carlos A Higuera
Jaiben George
Prosthetic joint infection (PJI) is a serious complication after total joint arthroplasty (TJA). Chlorhexidine is a widely used antiseptic because of its rapid and persistent action. It is well tolerated and available in different formulati...
Treatment of Periprosthetic Joint Infection Using Antimicrobials: Dilute Povidone-Iodine Lavage [0.03%]
使用抗生素治疗关节置换术后感染：碘伏稀释液冲洗疗法
John A Ruder,Bryan D Springer
John A Ruder
Periprosthetic joint infections (PJI) remain a challenge for the orthopaedic surgeon to treat and remain a leading cause of failure of both primary and revision total joint arthroplasty. Once a PJI develops, surgical treatment is generally ...
Min Lu,Erik Nathan Hansen
Min Lu
As the burden of deep hardware infections continues to rise in orthopaedics, there is increasing interest in strategies for more effective debridement of colonized tissues and biofilm. Hydrogen peroxide has been used medically for almost a ...
Antonia F Chen,Heinz Winkler
Antonia F Chen
The purpose of this special issue of Journal of Bone and Joint Infection is to provide orthopaedic surgeons with basic science explanations as to how these local antimicrobials work, clinical evidence that supports these local treatments, a...