Gentamicin fails to eradicate Staphylococcus aureus biofilm in vitro, even in combination with rifampin [0.03%]
庆大霉素不能清除金黄色葡萄球菌生物被膜体外实验中联合利福平也无法起效
Willemijn Boot,Michel Schläppi,Virginia Post et al.
Willemijn Boot et al.
Introduction: Biofilm formation is one of the key elements making orthopaedic device-related infections (ODRIs) difficult to eradicate. Aminoglycosides such as gentamicin are frequently applied via local carriers, and systemic rifampin is a...
Hussam Tabaja,Matteo Passerini,Irene G Sia et al.
Hussam Tabaja et al.
Lyme periprosthetic joint infection (PJI) is rare, with only 8 cases reported in the literature. In this paper, we describe 2 cases and review the prior 8 cases to better characterize its diagnosis and management. All 10 cases presented wit...
Diagnosis and management of fracture-related infections in a low-income country: a prospective study comparing current practice to international consensus guidelines [0.03%]
低收入国家骨折相关感染的诊断与治疗：一项前瞻性研究，对比现行方案和国际共识指南的区别
Loïc Fonkoué,Elizabeth K Tissingh,Cilia Ngang et al.
Loïc Fonkoué et al.
Data on the implementation of international consensus guidelines for fracture-related infection (FRI) in low- and middle-income countries (LMICs) are scarce. This study assessed whether FRI diagnosis and management in an LMIC align with the...
Synovial fluid specific gravity as an inexpensive point-of-care test for diagnosing hip and knee periprosthetic joint infection [0.03%]
关节滑膜液比重测定在髋、膝关节假体周围感染诊断中的应用价值研究
Sujeesh Sebastian,Hibah A Abusulaiman,Veronika Achatz et al.
Sujeesh Sebastian et al.
Synovial fluid specific gravity (SG) was evaluated as a rapid, inexpensive test for periprosthetic joint infection (PJI) diagnosis in revision arthroplasties. High diagnostic accuracy (area under the curve 0.89; threshold 1.007) with high s...
Fluoroquinolones vs. tetracycline agents combined with rifampicin for periprosthetic joint infections: a comparative study [0.03%]
氟喹诺酮类与四环素类联合利福平治疗关节置换术后感染的比较研究
Benoit Gachet,Olivier Robineau,Maxime Degrendel et al.
Benoit Gachet et al.
Objectives: Periprosthetic joint infections (PJIs) are predominantly caused by gram-positive bacteria. Fluoroquinolones (FQs), combined with rifampicin (RMP), are often used but may be unsuitable due to resistance, side effects, or intolera...
Osteomyelitis in peri-implant bone of hip prosthetic joint infection: prevalence and clinical impact [0.03%]
人工关节感染中假体周围骨髓炎的发病情况及临床影响
Ernesto Muñoz-Mahamud,Melissa Rivera,Ana Belén Larque et al.
Ernesto Muñoz-Mahamud et al.
Introduction: Periprosthetic joint infection (PJI) after hip revision surgery shows variable failure rates, with the impact of osteomyelitis in the surrounding bone on outcomes remaining unclear. This study aims to examine bone osteomyeliti...
The proportion of chronic periprosthetic joint infection patients with Candida isolates [0.03%]
慢性人工关节感染患者中念珠菌分离株的比例
Samuelson E Osifo,Adrian Santana,Michael F Shannon et al.
Samuelson E Osifo et al.
Introduction: Fungal periprosthetic joint infection (PJI) has historically been reported in 1 %-2 % of cases, with Candida species accounting for most isolates. However, the true incidence is likely underestimated. Standard aerobic and anae...
Predictors of osteo-articular infection in Staphylococcus aureus bacteremia in a tertiary center between 2017 and 2022 [0.03%]
2017至2022年三级医疗中心金黄色葡萄球菌菌血症患者骨关节感染的预测因素
Liselot Vandenbergen,Diego Castanares Zapatero,Sébastien Briol et al.
Liselot Vandenbergen et al.
Introduction: Among bloodstream infections, Staphylococcus aureus bacteremia (SAB) is associated with a particularly high mortality rate, which may be higher in patients with undiagnosed metastatic infections. The primary objective of the p...
Synovial fluid α-defensin might be false positive in early stages after major total arthroplasty revision surgery [0.03%]
关节大修术后早期滑膜液α-防御素可能假阳性
Sankalp Mrutyunjaya,Wade A Banta,Joseph R B Espiritu et al.
Sankalp Mrutyunjaya et al.
Generalizability is critical when evaluating the performance of a diagnostic test to ensure variations in the patient population are represented. We report a case of a patient receiving multiple false positive results from the synovial ^...
Renal safety of intraoperative local vancomycin powder application in orthopedic surgery: a retrospective analysis [0.03%]
骨科手术中术中局部万古霉素粉剂应用的肾安全性：一项回顾性分析
Juliane Beschauner,Maria Felsberg,Alexander Zeh et al.
Juliane Beschauner et al.
Introduction: Topical vancomycin powder is increasingly used in orthopedic surgery to prevent surgical site infections (SSIs). While its efficacy is well established, data on systemic safety - particularly renal effects - are limited. Given...