From Genomic Testing to Olaparib Treatment: Real-World Utilization and Outcomes in BRCA-Mutated Metastatic Castration-Resistant Prostate Cancer [0.03%]
Dianne Bosch,Kim J M van der Velden,Aart Beeker et al.
Dianne Bosch et al.
Background: In November 2020, olaparib became the first approved poly adenosine diphosphate (ADP)-ribose polymerase inhibitor (PARPi) for metastatic castration-resistant prostate cancer (mCRPC) with BRCA1/2 mutations (BRC...
Patient‑Reported Satisfaction in Relapsing-Remitting Multiple Sclerosis: Advantages of At‑Home Self‑Administered Subcutaneous Ofatumumab Versus Other High‑Efficacy Therapies [0.03%]
复发缓解型多发性硬化患者的报告满意度：居家自给皮下注射Ofatumumab与其它高效治疗方案的优势
Francesco Pastore,Emanuela Domenicone,Patrizia DellOro et al.
Francesco Pastore et al.
Background: Multiple sclerosis is an immune-mediated disorder characterized by demyelination and neurodegeneration. Disease-modifying therapies are available with a range of mechanisms of action, efficacies, safety profil...
Treatment Patterns in Patients with Late-Onset Myasthenia Gravis in Japan: An Insurance Claims Database Study [0.03%]
日本 late-onset 运动神经重症肌无力患者的治疗模式：保险索赔数据库研究
Akiyuki Uzawa,Makoto Samukawa,Shingo Konno et al.
Akiyuki Uzawa et al.
Background and objective: This study evaluated treatment patterns and oral corticosteroid (OCS) use in Japanese patients with myasthenia gravis, comparing late-onset (mean age 79.8 years) and early/adult-onset (mean age 6...
The Relevance of Lenvatinib in Advanced Hepatocellular Carcinoma: Insights from a Prospective Observational Cohort in South India [0.03%]
仑伐替尼治疗晚期肝细胞癌的疗效分析——南印度前瞻性观察队列研究的新见解
Joe Jose,Shibu V Ignatious,Thattungal Manoharan Anoop
Joe Jose
Background and objective: Lenvatinib is a multi-kinase inhibitor approved as a first-line therapy for advanced hepatocellular carcinoma. In India and other low- and middle-income countries, immune checkpoint inhibitor-bas...
An Observational Study to Determine the Real-Life Effectiveness of MP-AzeFlu in Asian Patients with Allergic Rhinitis [0.03%]
一项观察性研究 在这项研究中确定了MP-鼻用氟替卡松在亚洲过敏性鼻炎患者中的实际疗效
Pongsakorn Tantilipikorn,Yau Kay Chung Julian,Te-Huei Yeh et al.
Pongsakorn Tantilipikorn et al.
Background: Allergic rhinitis (AR) is highly prevalent in Asia, but limited data exist on the real-world effectiveness of MP-AzeFlu (azelastine/fluticasone combination nasal spray) in Asian populations. ...
First Real-World Data of Olaparib Combination Treatment with Abiraterone and Prednisone or Prednisolone in First-Line Metastatic Castration-Resistant Prostate Cancer (mCRPC): Descriptive Analysis of 154 Patients Enrolled in the Early Access Program in France [0.03%]
奥拉帕利联合阿比特龙和泼尼松或泼尼松龙治疗初治转移性去势抵抗性前列腺癌（mCRPC）的首个真实世界数据：法国早期使用项目入组的154例患者的描述性分析
Louis Marie Dourthe,Aline Guillot,Cécile Vassal et al.
Louis Marie Dourthe et al.
Background: Olaparib, a poly ADP-ribose polymerase inhibitor, was approved by the European Commission in December 2022 and for which the Health for technology Assessment (HtA body) issued a favorable opinion for reimburse...
Regional Trends in the Opioid Epidemic Using Safety Signals of Drug Abuse and Dependence: A Disproportionality Analysis Using VigiBase [0.03%]
基于VigiBase数据库的安全信号 disproportionality分析：美国不同地区 opioid 流行趋势研究
Bohyun Suh,Hyung Suk Oh,Ju-Young Shin et al.
Bohyun Suh et al.
Background: The opioid epidemic, once a major concern in the United States, has escalated worldwide through three waves driven by prescription and synthetic opioids like oxycodone and fentanyl. Regional patterns of misuse...
Prevalence, Clinical Characteristics, and Factors Associated with Capecitabine-Induced Hand-Foot Syndrome in Patients with Cancer: Evidence from Sudan [0.03%]
苏丹癌症患者卡培他滨致手足综合症的流行率、临床特征及影响因素：横断面研究
Ola K Obeid,Bashir A Yousef,Yousif B Hamadalneel et al.
Ola K Obeid et al.
Background: Hand‒foot syndrome (HFS) is a common cutaneous toxicity of capecitabine that can impair treatment continuity and quality of life. This study aimed to assess the prevalence, clinical characteristics, and facto...
Trends in First-Time Symptomatic Antidementia Drug Dispensations to Home-Dwelling People in Norway: A Nationwide Register-Based Study [0.03%]
挪威居住在家中的首次出现症状的抗痴呆药物发放趋势：一项基于全国登记的研究
Torunn Gudmestad Øvrebø,Anita L Sunde,Arvid Rongve et al.
Torunn Gudmestad Øvrebø et al.
Background: Symptomatic antidementia drugs can influence cognitive symptoms. According to Norwegian dementia guidelines, general practitioners (GPs) are responsible for assessing, treating, and following up on dementia, w...
Disease Burden in Transfusion-Dependent β-Thalassemia (TDT) Patients and Caregivers in Italy: Results of a Cross-Sectional Descriptive Online Survey [0.03%]
意大利输血依赖性β型地中海贫血(TDT)患者和看护者的疾病负担：一项横断面在线调查的描述性结果
Marcella Contieri,Francesca Gatta,Maria Colonnese et al.
Marcella Contieri et al.
Background: Patients with transfusion-dependent thalassemia (TDT) require lifelong blood transfusions; data on the psychosocial and economic impact on patients and their caregivers remain limited. The study aims to addres...