Safety and Effectiveness of a Fixed-Dose Combination of Cephalexin Extended Release and Clavulanate Potassium in Bacterial Sore Throat and Uncomplicated Skin and Soft-Tissue Infections: A Multicentre, Open-Label, Phase IV Study in India [0.03%]
头孢拉定缓释片与钾克拉维酸固定剂量复方制剂治疗细菌性咽炎和 uncomplicated皮肤及软组织感染安全性和有效性的多中心开放标签IV期研究：印度临床试验报告
Sunil Panda,Shrinivas Chavan,Sumit Agarwal et al.
Sunil Panda et al.
Background and objectives: Respiratory tract infections and skin and soft-tissue infections are some of the most common causes of outpatient visits. Upper respiratory tract infections (URTIs) are the most common type of i...
Trends in Adverse Event Reports of Dipeptidyl Peptidase-4 Inhibitor-Associated Pemphigoid in Japan [0.03%]
日本DPP-4抑制剂相关类天疱疮不良事件报告的流行趋势分析
Akina Takami,Gen Terashima,Takumi Tajima et al.
Akina Takami et al.
Background: Dipeptidyl peptidase-4 (DPP-4) inhibitors are widely used as a first-line therapy for type 2 diabetes in Japan. Precautions of the package inserts for ethical drugs containing DPP-4 inhibitors were revised for...
Real-World Experience with Selexipag in Patients with Pulmonary Arterial Hypertension: Treatment Patterns and Outcomes across Baseline Risk Strata (SPHERE and EXPOSURE Studies) [0.03%]
波生坦在肺动脉高压患者中的真实世界经验：不同基线风险人群的治疗模式和预后结果（SPHERE 和 EXPOSURE 研究）
Pilar Escribano Subias,Murali M Chakinala,Kelly M Chin et al.
Pilar Escribano Subias et al.
Background: Treatment strategies for pulmonary arterial hypertension (PAH) depend on patients' 1-year mortality risk; however, real-world practices and outcomes remain inadequately described. ...
Survival Outcomes with Guideline-Concordant Pediatric-Inspired Regimens in Adolescent/Young Adult Acute Lymphoblastic Leukemia: Retrospective Real-World Analysis [0.03%]
基于儿科治疗方案的青少年及年轻成人急性淋巴细胞白血病患者的预后：回顾性真实世界分析
David R Freyer,Jian Zhu,Michael E Roth et al.
David R Freyer et al.
Background: Pediatric-inspired regimens (PIR) yield excellent outcomes for acute lymphoblastic leukemia (ALL). Despite national guidelines recommending PIR for adolescents and young adults (AYAs; aged 15-39 years), the us...
Evaluation of Effectiveness and Safety of Telmisartan and Amlodipine Fixed-Dose Combination in Indian Patients with Hypertension: TACT-India Study [0.03%]
印度高血压患者使用替米沙坦和氨氯地平固定剂量复方制剂疗效及安全性的评价：TACT-INDIA研究
Ashok Kumar Das,Mangesh Tiwaskar,Jabir Abdullakutty et al.
Ashok Kumar Das et al.
Background: Hypertension is a major global health burden associated with significant cardiovascular morbidity and mortality. Fixed-dose combinations (FDC) may improve blood pressure (BP) control and prevent associated com...
Comparison of Opioid Utilization in Older Adults with Rheumatoid Arthritis before and after Initiating Biological or Targeted Synthetic Disease-Modifying Antirheumatic Drugs [0.03%]
生物制剂或靶向合成抗风湿病药物诱导前后的老年类风湿关节炎患者阿片类药物使用情况比较
Yinan Huang,Shadi Bazzazzadehgan,Liang-Yuan Lin et al.
Yinan Huang et al.
Introduction: Opioid use is common in rheumatoid arthritis (RA) for pain management; however, evidence of opioid-associated adverse events is increasing. While biological (b) or targeted synthetic (ts) disease-modifying a...
Effectiveness and Safety of the Novel Selective Urate Reabsorption Inhibitor Dotinurad After Switching from Febuxostat in Patients with Stage B/C Heart Failure [0.03%]
替洛利司用于痛风且合并中重度心力衰竭患者的安全性和有效性：富马酸febuxostat治疗后切换的中文研究
Tsutomu Murakami,Yuki Watanabe,Norihito Nakamura et al.
Tsutomu Murakami et al.
Background: Hyperuricemia is a common comorbidity in patients with cardiovascular diseases and chronic kidney disease, often requiring long-term urate-lowering therapy. Febuxostat, a xanthine oxidase inhibitor, has raised...
Use of Carbimazole, Methimazole and Propylthiouracil in Women of Childbearing Age and Exposed Pregnancies in Germany: A Population-Based Study [0.03%]
基于人口的德国女性育龄期使用卡比马唑、甲巯咪唑和丙基硫氧嘧啶的研究及暴露妊娠研究
Tania Schink,Maxim Frizler,Bianca Kollhorst et al.
Tania Schink et al.
Background: Hyperthyroidism during pregnancy is associated with maternal, obstetric and fetal complications. Antithyroid drugs (ATDs) including carbimazole (CMZ), methimazole (MMI) and propylthiouracil (PTU) are the main ...
Health Equity Concerns in People with Sickle Cell Disease and Recurrent Vaso-Occlusive Crises: Results from an International Survey Study [0.03%]
一项国际调查研究： sickle细胞病患者血管阻塞反复发作的健康公平性问题结果报告
Adriana Boateng-Kuffour,Lauren Lilly,Jennifer Drahos et al.
Adriana Boateng-Kuffour et al.
Background: Vaso-occlusive crises (VOCs) are a hallmark of sickle cell disease (SCD). Individuals with SCD often report stigma and negative healthcare provider (HCP) attitudes when seeking treatment. This study examines h...
Use of Potentially Inappropriate Medication and Association with Falls During Hospitalisation: An Analysis Based on Electronic Health Records (POLAR_MI project) [0.03%]
基于电子健康记录的不适当用药与住院期间跌倒的相关性分析(POLAR_MI项目)
Louisa Redeker,Miriam Kesselmeier,Beate Mussawy et al.
Louisa Redeker et al.
Background: In an ageing population, drug-related problems, including potentially inappropriate medications (PIMs), are increasingly relevant. PIM lists are important tools for improving medication safety in older adults....