Fetal Mesenchymal Stromal Cells: an Opportunity for Prenatal Cellular Therapy [0.03%]
胎儿间充质干细胞：宫内细胞治疗的机会与挑战
Rachel Sagar,Lilian Walther-Jallow,Anna L David et al.
Rachel Sagar et al.
Purpose of review: The aim of the study is to provide an overview on the possibility of treating congenital disorders prenatally with mesenchymal stromal cells (MSCs). ...
Brian Nankervis,Mark Jones,Boah Vang et al.
Brian Nankervis et al.
Purpose of review: Recent developments in regenerative medicine have precipitated the need to expand gene-modified human T cells to numbers that exceed the capacity of well-plate-based, and flask-based processes. This rev...
Nafiisha Genet,Neha Bhatt,Antonin Bourdieu et al.
Nafiisha Genet et al.
Purpose of review: Considerable progress has been made in the field of stem cell research; nonetheless, the use of stem cells for regenerative medicine therapies, for either endogenous tissue repair or cellular grafts pos...
The Role of Intestinal Stem Cells in Epithelial Regeneration Following Radiation-Induced Gut Injury [0.03%]
辐射诱导的肠道损伤后肠上皮再生过程中肠干细胞的作用
Chang-Kyung Kim,Vincent W Yang,Agnieszka B Bialkowska
Chang-Kyung Kim
Purpose of review: Intestinal epithelial cells show remarkable plasticity in regenerating the epithelium following radiation injury. In this review, we explore the regenerative capacity and mechanisms of various populatio...
Jacob H Jordahl,Luis Villa-Diaz,Paul H Krebsbach et al.
Jacob H Jordahl et al.
Stem cells have the ability to self-renew and differentiate into specialized cell types, and, in the human body, they reside in specialized microenvironments called "stem cell niches." Although several niches have been described and studied...
Sarah M Smith,Charles L Limoli
Sarah M Smith
Purpose of review: To encapsulate past and current research efforts focused on stem cell transplantation strategies to resolve radiation-induced cognitive dysfunction. ...
NK Cells and γδT Cells for Relapse Protection After Allogeneic Hematopoietic Cell Transplantation (HCT) [0.03%]
allo-HCT后复发防护的NK和γδ T细胞的研究
Moniek A de Witte,Jürgen Kuball,Jeffrey S Miller
Moniek A de Witte
Purpose of review: The outcome of allogeneic stem cell transplantation (allo-HCT) is still compromised by relapse and complications. NK cells and γδT cells, effectors which both function through MHC-unrestricted mechani...
Radiotherapy and Glioma Stem Cells: Searching for Chinks in Cellular Armor [0.03%]
放射治疗与胶质瘤干细胞：寻找细胞的弱点
Seamus P Caragher,Sean Sachdev,Atique Ahmed
Seamus P Caragher
Purpose of the review: Radiation became a pillar of oncologic treatment in the last century and provided a powerful and effective locoregional treatment of solid malignancies. After achieving some of the first cures in ly...
The Axolotl Limb Regeneration Model as a Discovery Tool for Engineering the Stem Cell Niche [0.03%]
轴口螈肢体再生模型作为工程化干细胞生态位的发现工具
Negar Seyedhassantehrani,Takayoshi Otsuka,Shambhavi Singh et al.
Negar Seyedhassantehrani et al.
Purpose of review: Recent advances in genomics and gene editing have expanded the range of model organisms to include those with interesting biological capabilities such as regeneration. Among these are the classic models...
Loriana Vitillo,Susan J Kimber
Loriana Vitillo
Purpose of review: Human pluripotent stem cells (hPSCs) are anchorage-dependent cells that can be cultured on a variety of matrices and express integrins and the machinery for integrin signaling. Until recently, there has...