Subcutaneous Belimumab Demonstrates Consistent Steady-State Pharmacokinetics and is Well Tolerated in Paediatric Patients with SLE in China: An Open-Label Study [0.03%]
皮下注射倍力腾治疗中国系统性红斑狼疮儿科患者疗效良好且耐受性佳：开放标签研究
Caifeng Li,Junmei Zhang,Meiping Lu et al.
Caifeng Li et al.
Introduction: This study assessed pharmacokinetics and safety of subcutaneous (SC) belimumab in Chinese paediatric patients with systemic lupus erythematosus (cSLE) who previously received intravenous (IV) belimumab; only...
Longitudinal Instability of Minimal Disease Activity Domains in Psoriatic Arthritis with Fluctuating Response: A Trajectory Analysis of a Real-World Cohort [0.03%]
银屑病关节炎波动反应低疾病活动度域的纵向不稳定性：真实世界队列的轨迹分析
Mauro Fatica,Fabio Massimo Perrotta,Noemi Italiano et al.
Mauro Fatica et al.
Introduction: Minimal disease activity (MDA) is a composite tool used to measure disease state in psoriatic arthritis (PsA), but its longitudinal stability across individual domains remains insufficiently understood. We a...
Filgotinib in Moderate to Severe Rheumatoid Arthritis in a Real-World Setting: Up to 6-Month Effectiveness, Patient-Reported Outcomes, and Persistence, and up to 24-Month Safety from More than 1400 Patients in the FILOSOPHY and PARROTFISH Studies [0.03%]
在现实世界中，filgotinib对中重度类风湿性关节炎疗效、患者报告结果和持续时间的6个月效果以及来自FILOSOPHY研究和PARROTFISH研究的24个月安全性：超过1400名患者的资料
Gerd R Burmester,James Galloway,Karen Bevers et al.
Gerd R Burmester et al.
Introduction: FILOSOPHY (NCT04871919) and PARROTFISH (NCT05323591) are ongoing, prospective observational European phase 4 studies of filgotinib in patients with rheumatoid arthritis (RA) in a real-world setting. We repor...
Persistence Among Biologic/JAKi-Naive Medicare Beneficiaries with RA Initiating Synthetic DMARDs [0.03%]
生物制剂/JAKi初治的医保收益者启动传统疾病修正药物治疗后的持续性研究
Taylor T Schwartz,Hanke Zheng,Laetitia N&#x;Dri et al.
Taylor T Schwartz et al.
Introduction: Persistence to therapy to treat rheumatoid arthritis (RA) is an indirect measure of tolerability and effectiveness in the real-world setting. Previous clinical trials suggested that seropositive patients wit...
Long-term Comparative Adherence and Switch Rates in Patients Receiving Advanced Therapies for Rheumatoid Arthritis After Use of One TNF Inhibitor [0.03%]
患者使用一种TNF抑制剂治疗失败后接受先进疗法治疗类风湿性关节炎的长期依从性和换药率的比较研究
Christina Charles-Schoeman,Kurt Oelke,Patrick M Zueger et al.
Christina Charles-Schoeman et al.
Introduction: Patients with rheumatoid arthritis (RA) often fail to achieve treatment targets with first-line treatment because of poor efficacy or tolerability. However, comparative long-term adherence and switching data...
Duration of Belimumab Therapy and Timing of Initiation as Predictors of Clinical Outcomes in Childhood-Onset Systemic Lupus Erythematosus: A Real-World Retrospective Study [0.03%]
贝利木单抗治疗时长及其起始时机对儿童期发病狼疮患者临床结局的影响：一项回顾性研究
Baixu Sun,Shipeng Li,Fengqiao Gao et al.
Baixu Sun et al.
Introduction: Belimumab is the only biologic approved for childhood-onset systemic lupus erythematosus (cSLE), yet evidence on the optimal timing of initiation and duration of therapy remains limited. This study aimed to ...
Comparison of Systemic Corticosteroid Therapy Practices Between Pediatric and Adult Rheumatologists: A Multicenter Survey Study [0.03%]
儿科和成人风湿病学专家全身皮质类固醇疗法实践对比：一项多中心调查研究
Övgü Özenli Yağcı,Çisem Yıldız,Deniz Gezgin Yıldırım et al.
Övgü Özenli Yağcı et al.
Introduction: The indications, dosage, and duration of systemic corticosteroid treatment may vary among pediatric rheumatologists (PRs) and adult rheumatologists (ARs) in daily clinical practice. This study aims to evalua...
Psychological Aspects of Rheumatic Diseases: Psychorheumatology in Clinical Practice [0.03%]
风湿病的心理学方面：临床心理风湿病学
Domniki M Karagianni,Christina G Katsiari,Konstantinos Bonotis et al.
Domniki M Karagianni et al.
Rheumatic diseases (RDs) significantly impact patients' physical, psychological, and social well-being, yet psychological dimensions remain inadequately addressed in routine clinical practice. In this commentary, we examine psychological ma...
Effectiveness and Safety of Inebilizumab for IgG4-Related Disease in a Real-World Clinical Setting in Japan: Protocol for a Long-Term Prospective Observational Study (4SigHT Study) [0.03%]
伊那西珠单抗治疗IgG4相关性疾病日本真实世界有效性、安全性的长期前瞻性观察研究（4SigHT 研究）方案
Yoshiya Tanaka,Yuzo Kodama,Shingo Nakayamada et al.
Yoshiya Tanaka et al.
Introduction: IgG4-related disease (IgG4-RD) is a systemic fibroinflammatory condition that can cause irreversible organ dysfunction and life-threatening complications. Although glucocorticoids are the standard first-line...
Optical Spectral Transmission Imaging in Patients with Osteoarthritis: A Comparative Study with Joint Ultrasound and Clinical Markers [0.03%]
骨关节炎患者光学光谱传输成像与关节超声及临床标志物的比较研究
Konstantinos Triantafyllias,Stefanie Liverakos,Khalid K Altamimi et al.
Konstantinos Triantafyllias et al.
Introduction: This study aimed to evaluate the diagnostic performance of optical spectral transmission (OST) in patients with hand osteoarthritis (OA) and to assess its associations with clinical findings, joint ultrasoun...