Chemoprotective epigenetic mechanisms in a colorectal cancer model: Modulation by n-3 PUFA in combination with fermentable fiber [0.03%]
ω-3多不饱和脂肪酸联合可发酵纤维对结直肠癌模型化学保护表观遗传机制的调节作用研究
Karen Triff,Eunjoo Kim,Robert S Chapkin
Karen Triff
Colorectal cancer is the third major cause of cancer-related mortality in both men and women worldwide. The beneficial role of n-3 polyunsaturated fatty acids (PUFA) in preventing colon cancer is substantiated by experimental, epidemiologic...
MicroRNA Regulating Glutathione S-Transferase P1 in Prostate Cancer [0.03%]
微小核糖核酸调控前列腺癌中的谷胱甘肽S转移酶P1表达
Savita Singh,Girish C Shukla,Sanjay Gupta
Savita Singh
Glutathione S-transferase P1 (GSTP1), an enzyme involved in detoxification process, is frequently inactivated in prostate cancer due to epigenetic modifications. Through in silico analysis we identified a subset of miRNAs that are putative ...
The Epigenetic Impact of Cruciferous Vegetables on Cancer Prevention [0.03%]
cruciferous蔬菜对癌症的表观遗传影响
Kendra J Royston,Trygve O Tollefsbol
Kendra J Royston
The answer to chemoprevention has perhaps been available to the general public since the dawn of time. The epigenetic diet is of extreme interest, for research suggests that cruciferous vegetables are not only an important source of nutrien...