Artificial Olfactory System Enabled by Ultralow Chemical Sensing Variations of 1D SnO2 Nanoarchitectures [0.03%]
基于一维SnO2纳米结构的超低化学传感变化的仿生嗅觉系统
Yun-Haeng Cho,Dong-Su Kim,Jung Hwan Seo et al.
Yun-Haeng Cho et al.
AI-assisted electronic nose systems often emphasize sensitivity-driven datasets, overlooking the comprehensive analysis of gaseous chemical attributes critical for precise gas identification. Conventional fabrication methods generate incons...
Proteomics-Empowered Microfluidic-SERS Immunoassay for Identifying and Detecting Biomarkers of Micropapillary Lung Adenocarcinoma [0.03%]
基于蛋白质组学的微流控SERS免疫检测技术用于微乳头型肺腺癌生物标志物的识别与检测
Dechun Zhang,Kaiming Peng,Hui Xu et al.
Dechun Zhang et al.
The presence of a micropapillary (MPP) component is a crucial determinant of surgical strategies for lung adenocarcinoma (LUAD), yet reliable blood biomarkers for predicting MPP⁺ LUAD remain elusive. Here, we integrate 4D label-free quanti...
Plasma DNMT1 Activity for Assessing Tumor Burden and Predicting Neoadjuvant Therapy Response in Breast Cancer [0.03%]
乳腺癌中用于评估肿瘤负荷和预测新辅助治疗反应的血浆DNMT1活性
Yingran Wang,Guozhi Zhang,Zhizhao Zhang et al.
Yingran Wang et al.
DNA methylation is mediated by DNA methyltransferases (DNMTs), and the stability of their activity is essential for cellular fate. DNMT1 is considered one of the most promising targets for research. However, current detection techniques are...
Unveiling the Excited-State Dynamics and Interfacial Interactions in Dye-Sensitized NaNdF4 Nanoparticles for Efficient Photothermal Effect [0.03%]
用于高效光热效应的染料敏化NaNdF4纳米粒子的动力学和界面相互作用研究
Jiacheng Gong,Wusen Zhou,Zhuo Li et al.
Jiacheng Gong et al.
Near-infrared (NIR) dyes can overcome the weak absorption of lanthanide nanoparticles (NPs) by antenna sensitization, offering new avenues to develop efficient and versatile lanthanide nanomaterials. However, current research on dye-sensiti...
Gradient Solvent Replacement-Mediated Formation of High-Strength Hydrogel-Forming Microneedle for Long-Term Drug Delivery [0.03%]
基于梯度溶剂置换的高强度药物递送微针透皮给药系统
Hui Li,Fengzhen Meng,Chengwei Hu et al.
Hui Li et al.
The microneedle, a minimally invasive transdermal system, provides a convenient and painless method for drug delivery. Among the various types of microneedles, hydrogel-forming microneedles (HFMs) demonstrate distinct advantages in terms of...
LRRC4 Deficiency Drives Premature Ovarian Insufficiency by Disrupting Metabolic Homeostasis in Granulosa Cells [0.03%]
LRRC4缺乏通过破坏颗粒细胞代谢稳态驱动早发性卵巢功能不全
Yujie Shang,Yunjun Li,Di Han et al.
Yujie Shang et al.
Premature ovarian insufficiency (POI), defined by early loss of ovarian activity before the age of 40 years, is the leading cause of infertility and systematic aging in women, posing a public health challenge worldwide. However, its molecul...
Luke Mizzi,Krzysztof K Dudek,Andrea Frassineti et al.
Luke Mizzi et al.
Hierarchical auxetic metamaterials are a class of materials which are characterized by a multi-tiered architecture and have the capability of exhibiting enhanced mechanical properties in comparison to their single-geometry counterparts. In ...
Functionalized Biomimetic Nanoparticles Targeting the IL-10/IL-10Rα/Glycolytic Axis in Synovial Macrophages Alleviate Cartilage Degeneration in Osteoarthritis [0.03%]
功能化仿生纳米颗粒靶向滑膜巨噬细胞中的IL-10 / IL-10Rα /糖酵解轴可缓解骨关节炎软骨退变
Wenwei Li,Yang Liu,Ming Wei et al.
Wenwei Li et al.
Osteoarthritis (OA) is a low-grade inflammatory disease that is highly associated with severe hyperplasia of the synovial membrane and the degeneration of cartilage. Interleukin-10 (IL-10), has been extensively studied, while its receptor, ...
Real-Time Self-Optimization of Quantum Dot Laser Emissions During Machine Learning-Assisted Epitaxy [0.03%]
机器学习辅助外延生长过程中量子点激光器发射的实时自优化
Chao Shen,Wenkang Zhan,Shujie Pan et al.
Chao Shen et al.
Traditional methods for optimizing light source emissions rely on a time-consuming trial-and-error approach. While in situ optimization of light source gain media emission during growth is ideal, it has yet to be realized. In this work, in ...
scCompass: An Integrated Multi-Species scRNA-seq Database for AI-Ready [0.03%]
scCompass：一个集成的多物种单细胞 RNA 测序数据库（支持人工智能）
Pengfei Wang,Wenhao Liu,Jiajia Wang et al.
Pengfei Wang et al.
Emerging single-cell sequencing technology has generated large amounts of data, allowing analysis of cellular dynamics and gene regulation at the single-cell resolution. Advances in artificial intelligence enhance life sciences research by ...