NiH-Catalyzed Enantio- and Regioselective Hydroselenylation of Unactivated Alkenes [0.03%]
镍催化未活化烯烃的对映和区域选择性水硒化反应
Hyung-Joon Kang,Jaehun Kim,Sungwoo Hong
Hyung-Joon Kang
Chiral alkyl selenides are valuable motifs in medicinal chemistry and redox-active molecular design, yet enantioselective hydroselenylation of unactivated alkenes remains challenging due to limited control over regio- and enantioselectivity...
Matrix Stiffness Enhances Odontogenic Differentiation of DPSCs through Membrane Curvature Protein Baiap2-Modulated Exosome Release [0.03%]
基质刚度通过膜曲率蛋白Baiap2调节的外泌体释放促进DPSCs成odontogenic分化
Bilun Jin,Shaojie Dong,Yue Jia et al.
Bilun Jin et al.
Altered extracellular biomechanical forces are increasingly implicated in a wide range of pathologies. However, the specific role of extracellular matrix stiffness in the pathogenesis of dental caries remains unclear. Although exosomes have...
Coexisting Volatile and Nonvolatile Switching in 3D ALD-IGZO Vertical RRAM for Fully Hardware-Based Wide Reservoir Computing [0.03%]
基于全硬件的宽水库计算的3D原子层沉积氧化物垂直RRAM中的共存易失性和非易失性开关效应
Seeun Lee,Jaewon Park,Nawoon Kim et al.
Seeun Lee et al.
Although indium-gallium-zinc oxide (IGZO) has been widely used in thin-film transistors (TFTs), its application as an active switching medium in resistive random-access memory (RRAM) has remained relatively less explored, particularly for v...
Conditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L [0.03%]
条件性显著的eQTL和TWAS分析鉴定出MsRD26是盐胁迫下紫花苜蓿主要的正调控候选基因
Lin Chen,Yuqi Zhang,Xinyue Ma et al.
Lin Chen et al.
Natural variation in gene expression bridges genetic polymorphisms and phenotypic divergence, yet the regulatory architecture underlying salt stress responses remains largely unexplored in alfalfa. Here, we generated 528 RNA-seq libraries f...
Programmed Interfacial Phase Separation for Spatiotemporal Fungicide Delivery via Tunable Micro/Nano Architectures [0.03%]
通过可调微/纳米结构实现时空 fungicide 释放的程序化界面相分离
Rui Zhang,Tongfang Jing,Leiming He et al.
Rui Zhang et al.
Translating dynamic liquid-liquid phase separation into robust solid-state architectures remains a challenge in materials engineering. Here, we report a composition-driven interfacial assembly strategy that couples supramolecular coacervati...
Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain [0.03%]
靶向作用于伤害性感觉神经元的CXCR2在术后镇痛中具有潜在应用价值
Yushuang Pan,Peiyi Li,Yufeng Chen et al.
Yushuang Pan et al.
Postoperative pain impairs patients' quality of life. Mechanisms underlying postoperative pain remain incompletely understood. We investigated postoperative pain in a mouse model of skin plus deep tissue incision (INC). We found Cxcl5 was a...
Engineering Large-Grain Metal Halide Perovskite Films via Chemical Vapor Deposition for High-Performance, Ultralow-Noise Perovskite Photodetectors [0.03%]
基于化学气相沉积的金属卤化物钙钛矿大晶粒薄膜及其高性能低噪声光探测器器件研究
Roel Vanden Brande,Sudipta Seth,Lei Gao et al.
Roel Vanden Brande et al.
Metal halide perovskites have emerged as promising semiconductors for high-performance photodetectors and X-ray sensors due to their high-Z composition, excellent charge transport, and intrinsic defect tolerance. However, scalable fabricati...
Engineering Large-Grain Metal Halide Perovskite Films via Chemical Vapor Deposition for High-Performance, Ultralow-Noise Perovskite Photodetectors [0.03%]
基于化学气相沉积的金属卤化物钙钛矿大晶粒薄膜及其高性能低噪声光电探测器研究
Roel Vanden Brande,Sudipta Seth,Lei Gao et al.
Roel Vanden Brande et al.
Metal halide perovskites have emerged as promising semiconductors for high-performance photodetectors and X-ray sensors due to their high-Z composition, excellent charge transport, and intrinsic defect tolerance. However, scalable fabricati...
PARP Inhibitors plus Anlotinib as Bridging Therapy for Armored CAR-T Cells in Ovarian Cancer Enhances Infiltration and Antitumor Efficacy [0.03%]
用于卵巢癌装甲CAR-T细胞的桥梁疗法PARP抑制剂联合安罗替尼可增强浸润和抗肿瘤疗效
Huayi Li,Minghua Xiang,Qiuyang Xu et al.
Huayi Li et al.
Chimeric antigen receptor (CAR)-T cell therapy is largely ineffective in most solid tumors, partially because of inadequate intratumoral trafficking. Bridging therapy, administered between leukapheresis and CAR-T cell infusion, offers a dis...
PARP Inhibitors plus Anlotinib as Bridging Therapy for Armored CAR-T Cells in Ovarian Cancer Enhances Infiltration and Antitumor Efficacy [0.03%]
用于装甲CAR-T细胞的PARP抑制剂联合安罗替尼在卵巢癌中的桥接治疗可增强肿瘤浸润和抗肿瘤疗效
Huayi Li,Minghua Xiang,Qiuyang Xu et al.
Huayi Li et al.
Chimeric antigen receptor (CAR)-T cell therapy is largely ineffective in most solid tumors, partially because of inadequate intratumoral trafficking. Bridging therapy, administered between leukapheresis and CAR-T cell infusion, offers a dis...