Precision-Guided Stealth Missiles in Biomedicine: Biological Carrier-Mediated Nanomedicine Hitchhiking Strategy [0.03%]
精密隐身导弹在生物医学中的应用——生物载体介导的纳米药物搭车策略
Yuyan Zhou,Xinyue Wang,Deyu Zhang et al.
Yuyan Zhou et al.
Nanodrug delivery systems (NDDS) have demonstrated broad application prospects in disease treatment, prevention, and diagnosis due to several advantages, including functionalization capability, high drug-loading capacity, drug stability pro...
An Atypical Heterojunction in Favor of Conversion of CO2 and Sunlight into C2H4 [0.03%]
一种非常规异质结助力CO2和太阳能制取C2H4
Qin He,Dongge Ma,Yangyang Du et al.
Qin He et al.
Current heterojunction semiconduction assemblies, including type I, II, Z-Scheme, and S-Scheme constructures, enable the utilization of longer-wavelength sunlight for photocatalytic conversions. However, such benefits are often achieved at ...
LincNEAT1 Encoded-NEAT1-31 Promotes Phagocytosis by Directly Activating the Aurora-A-PI3K-AKT Pathway [0.03%]
LincNEAT1编码的NEAT1-31通过直接激活Aurora-A-PI3K-AKT通路促进吞噬作用
Jie Li,Jing Zhang,Xixi Li et al.
Jie Li et al.
Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation. Long non-coding ribonucleic acid nuclear enriched abundant transcript 1 (LincNEAT1) is specif...
An Enhanced "Trapping-Conversion" Function Enables Ultrastable Potassium Ion Storage [0.03%]
增强的"捕获-转化"功能实现超稳定的钾离子存储
Zhongquan Wang,Bangjun Wu,Zhenping Qiu et al.
Zhongquan Wang et al.
Metal chalcogenides (MCs) have emerged as promising candidates for potassium ion battery (KIB) anode materials, yet the sluggish redox kinetics and notorious shuttle effect inescapability lead to inferior rate performance and poor cyclabili...
CD103+ T Cells Eliminate Damaged Alveolar Epithelial Type II Cells Under Oxidative Stress to Prevent Lung Tumorigenesis [0.03%]
氧化应激下CD103⁺T细胞清除肺泡II型上皮细胞预防肺癌发生
Yu Xu,Haorui Luo,Jiahao Wang et al.
Yu Xu et al.
The nexus between aging-associated immune deteriorations and tumorigenesis of lung cancers remains elusive. In a mouse model with Med23 depletion in T cells (Med23 -/-), it is found a strong association between the decline of CD103+ T cells...
Integrating Dense Genotyping with High-Throughput Phenotyping Empowers the Genetic Dissection of Berry Quality and Resilience Traits in Grapevine [0.03%]
将密集基因分型与高通量表型分析相结合，助力解剖葡萄果实品质和抗逆性状的遗传构造
Yuyu Zhang,Yongjian Wang,Michael Henke et al.
Yuyu Zhang et al.
Investigating the genetic architecture of important agronomic traits in grapevine, like berry quality and resilience to abiotic stress, has been hampered by bottlenecks in genotyping and phenotyping. To address these limitations, this study...
Attenuated Nuclear Tension Regulates Progerin-Induced Mechanosensitive Nuclear Wrinkling and Chromatin Remodeling [0.03%]
核张力减弱调节progerin诱导的机械敏感性核皱纹和染色质重塑
Ji-Eun Park,Juhyeon Jo,Kun Xu et al.
Ji-Eun Park et al.
Hutchinson-Gilford progeria syndrome, caused by a mutation in the LMNA gene, leads to increased levels of truncated prelamin A, progerin, in the nuclear membrane. The accumulation of progerin results in defective nuclear morphology and is a...
Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice [0.03%]
磷脂酰胆碱对中华老年人和SAMP8小鼠记忆减退和肌肉萎缩的改善作用
Xianyun Wang,Dajun Li,Xiao Ying Li et al.
Xianyun Wang et al.
Identifying the mechanistic targets of crosstalk between sarcopenia (SA) and mild cognitive impairment (MCI) is critical for screening high-risk populations and exploring effective prevention and treatment strategies. In a nationwide multic...
Breaking the Recycling Bottleneck of Thermosets via Bio-Tailoring Technology [0.03%]
利用生物修饰技术突破热固性塑料的回收瓶颈
Jinping Yu,Huan Wang,Yang Xu et al.
Jinping Yu et al.
Thermosets present significant recycling challenges due to irreversible chemical crosslinking, resulting in resource waste and environmental pollution. This paper introduces a new strategy for designing thermosets with excellent recycling p...
Xiayidan Maimaitikelimu,Zhiyan Xuan,Haoyu Ren et al.
Xiayidan Maimaitikelimu et al.
The number of people with hearing loss disorders is enormous, causing great physical and mental stress to patients, as well as a huge social burden. Among these patients, hearing loss caused by inner ear lesions accounts for a large proport...