Volumetric Engineered 3D Drug Reservoir Against Diabetic Implant Infection via Cuproptosis-Like Bacterial Death and Hunger-Triggered Maintenance of Mitochondrial Integrity [0.03%]
一种体外工程的3D药物储存库对抗糖尿病植入物感染并通过类铜死亡细菌杀灭和饥饿触发线粒体完整性维持发挥作用
Dize Li,Hongrui Qin,Min Jiang et al.
Dize Li et al.
Implant-associated infections in diabetic patients pose critical challenges due to immune-metabolic dysregulation that exacerbates biofilm persistence and tissue damage. This study introduces a "dimensional rise" strategy integrating 3D-pri...
Direct Observation of Suppressed Optical-Acoustic Phonon Energy Coupling in Supported SWCNT at Cryogenic Temperatures [0.03%]
关于支持底物上石墨烯纳米带中声子能量耦合的抑制效应的直接观察
Ibrahim Al Keyyam,Yu Hua,Baini Li et al.
Ibrahim Al Keyyam et al.
Nonequilibrium among phonon branches critically influences nanoscale heat transport yet remains largely unexplored in one-dimensional (1D) systems, particularly at cryogenic temperatures. This work reports the first experimental quantificat...
Dong Chen,Gengzhuo Liu,Hongyan Du et al.
Dong Chen et al.
The evolving SARS-CoV-2 virus threatens global public health, particularly with potential resistance to PAXLOVID, whose active ingredient, nirmatrelvir, targets the viral main protease (Mpro). CAPTURE (direCted flAg laPlacian Transformer fo...
Manipulating Liquid-Liquid Interphase Solute Diffusion for the Construction of Non-Symmetric Metal-Quinone Network Nanoarchitectonics and Nano-Motorization [0.03%]
用于构建非对称金属-醌网络纳米结构和纳米推进的液液界面溶质扩散调控
Wenzhe Xu,Yingke Xue,Yang Chen et al.
Wenzhe Xu et al.
Non-symmetric nanoarchitectonics have demonstrated superior performance in nanotherapeutics compared to their symmetric counterparts, particularly in the design of self-propelled nanodrug delivery systems. However, achieving precise morphol...
Data-Driven Printability Modeling of Hydrogels for Precise Direct Ink Writing Based on Rheological Properties [0.03%]
基于流变学性质的光固化树脂精密直写打印适打性数据驱动模型构建方法研究
Eun Hui Jeong,Jiho Choi,Han Bi Park et al.
Eun Hui Jeong et al.
Hydrogels are gaining significant attention in soft robotics and electronics due to their favorable mechanical properties and sustainability. While hydrogel inks enable three-dimensional (3D) printing as a key fabrication technique, the rel...
Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C [0.03%]
基于皮肤类器官的再生黑素细胞文身创造方法及胶原蛋白VI和Semaphorin 3C介导的动态分布机制研究
Tingting Li,Xinzhu Li,Xiao Xiang et al.
Tingting Li et al.
The color patterns of mammalian fur are determined by melanocytes' ability to respond to and adapt to microenvironmental cues. However, these patterns can be lost following injury or under pathological conditions, and the underlying biologi...
Silvio Heinschke,Jörg J Schneider
Silvio Heinschke
Influencing the adsorptive processes of gases by external stimuli is an ongoing research task of academic and technological relevance. Technologically external stimuli like pressure, vacuum, temperature, magnetic field, or electrical phenom...
Low-Temperature Annealing Triggered Abnormal Strengthening in a Complex Concentration Alloy via Evolutive Short-Range Ordering [0.03%]
低溫退火通過演化近程有序引起複雜濃度合金異?？捎稚胶蠂
Yihan Wang,Yuan Wu,Yong Yu et al.
Yihan Wang et al.
Low-temperature annealing is traditionally employed to relieve residual stresses in metallic materials, typically resulting in softening. However, a novel finding in the face-centered-cubic (fcc) CoNiV medium entropy alloy (MEA) is reported...
Engineered Foxp1high Exosomes Ameliorates Systemic Lupus Erythematosus [0.03%]
工程化的Foxp1high外泌体改善了系统性红斑狼疮病情
Luhan Niu,Qianmin Ou,Qianhui Ren et al.
Luhan Niu et al.
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by immune dysregulation and impaired Treg cell differentiation. Mesenchymal stem cell-derived exosomes (MSC-exos) hold promise for treating immune-related diseases, w...
3D Topological Inorganic Electrides: Screening, Properties, and Applications [0.03%]
三维拓扑无机电子体：筛选、性质及应用
Zhenzhou Guo,Weizhen Meng,Qianwen Zhang et al.
Zhenzhou Guo et al.
The convergence of inorganic electrides and topological quantum phenomena has ushered in novel paradigms for designing advanced quantum materials. While low-dimensional (0-2D) topological inorganic electrides have garnered considerable atte...