In Situ Converting Conformal Sacrificial Layer Into Robust Interphase Stabilizes Fluorinated Polyanionic Cathodes for Aqueous Sodium-Ion Storage [0.03%]
原位转化柔性牺牲层为坚固界面相以稳定多氟代聚阴离子钠电正极
Peng Gong,Shibo Chai,Xingjie Li et al.
Peng Gong et al.
Sodium vanadium oxy-fluorophosphates (NVOPF), as typical fluorinated polyanionic compounds, are considered high-voltage and high-capacity cathode materials for aqueous sodium-ion storage. However, the poor cycle life caused by interfacial d...
Bowei Li,Zhongyun Xie,Mengmeng Wang et al.
Bowei Li et al.
The brain plays a central role in aging and longevity in diverse model organisms. Morphological and functional alteration in the aging brain elicits age-associated neuronal dysfunctions. However, the primary mechanism deteriorating the brai...
Stereotyped Subclones Revealed by High-Density Single-Cell Lineage Tracing Support Robust Development [0.03%]
高密度单细胞谱系追踪揭示的发育稳健性的刻板印象亚克隆
Xiaoyu Zhang,Zizhang Li,Jingyu Chen et al.
Xiaoyu Zhang et al.
Robust development is essential for multicellular organisms. While various mechanisms contributing to developmental robustness are identified at the subcellular level, those at the intercellular and tissue level remain underexplored. This q...
NKX2-5/LHX1 and UHRF1 Establishing a Positive Feedback Regulatory Circuitry Drives Esophageal Squamous Cell Carcinoma through Epigenetic Dysregulation [0.03%]
NKX2-5/LHX1和UHRF1通过表观遗传失调建立正反馈调节环路驱动食管鳞状细胞癌
Xukun Li,Dandan Fan,Yong Li et al.
Xukun Li et al.
DNA methylation regulators play critical roles in modulating oncogenic driver genes in cancers. However, the precise mechanisms through which these DNA methylation regulators influence oncogenesis and clinical therapy have yet to be fully e...
High Specific Strength Eutectic High-Entropy Alloy: Collaborative Effects of TRIP, TWIP, and Nanoprecipitation [0.03%]
高强高韧 eutectic 高熵合金：TRIP/TWIP 和纳米析出的协同作用
Z Q Wang,X T Li,Z J Zhang et al.
Z Q Wang et al.
Eutectic high-entropy alloys (EHEAs), characterized by their combination of hard and ductile phases, hold broad application prospects in terms of mechanical properties. However, the current performance of these alloys is not satisfactory. H...
Dual Role of CRABP2 in Colorectal Cancer: Oncogenesis via Nuclear RB1 and Cytoplasmic AFG3L2/SLC25A39 Axis, While Limiting Liver Metastasis through Cytoplasmic AFG3L2/PINK1/Parkin-Mediated Mitophagy [0.03%]
CRABP2在结直肠癌中的双重作用：通过核RB1和细胞质AFG3L2/SLC25A39轴促进肿瘤发生，但通过细胞质AFG3L2/PINK1/Parkin介导的线粒体自噬限制肝转移
Chuanxin Tian,Sheng Yang,Chuan Zhang et al.
Chuanxin Tian et al.
Colorectal cancer (CRC) progression and metastasis involve numerous regulatory factors. Among these, cellular retinoic acid-binding protein 2 (CRABP2) has been implicated as both a tumor activator and suppressor. Here, it is aimed to clarif...
Dual-Function Ceramic Pigments for Energy-Efficient and Secure Autonomous Vehicles [0.03%]
节能安全自主车辆用双功能陶瓷颜料
Ik Hoon Jeong,Yong-Jun Seo,Jum Soo Hwang et al.
Ik Hoon Jeong et al.
The global automobile market continues to demonstrate robust growth and innovation potential. Vehicles have evolved into complex, technology-intensive platforms, and autonomous vehicles are anticipated to become commonplace in the near futu...
Ligand Engineering of Co-N4 Single-Atom Catalysts for Highly-Active and Stable Acidic Oxygen Evolution [0.03%]
工程配体的Co-N4单原子催化剂用于高效且稳定的酸性析氧反应
Taeyoung Jeong,Kiwon Kim,Byung-Hyun Kim et al.
Taeyoung Jeong et al.
The development of stable and efficient single-atom catalysts (SACs) for the oxygen evolution reaction (OER) in acidic media remains challenging. This work reports a novel NH3-assisted pyrolysis strategy to synthesize Co-N4 SACs with contro...
Sortilin-Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA-Encoded Lysosome-Targeting Chimera [0.03%]
基于mRNA编码的 lysotargeting 假酶实现膜蛋白的精准持续降解
Xin Chang,Xinyu Qiu,Xiaoning Tong et al.
Xin Chang et al.
Recent advances in lysosome-targeting degradation technologies have introduced strategies to regulate therapeutic membrane proteins (MPs), potentially transforming treatment paradigms. However, challenges persist, including limited degradat...
Constructing Palladium-Based Crystalline@Amorphous Core-Shell Heterojunctions for Efficient Formic Acid Oxidation [0.03%]
用于高效甲醛氧化的基于钯的晶型@非晶型核心-壳层异质结的构建
Huiling Li,Jingkun Yu,Yongming Sui et al.
Huiling Li et al.
Constructing crystalline@amorphous heterostructures allows nanomaterials to maintain high electrical conductivity of crystalline structures while acquiring abundant active sites from amorphous structure. This emerging strategy has attracted...