Optimized melanin production from marine-associated Bacillus sp. EGY7 as a sustainable precursor of carbon dots for biomedical applications [0.03%]
从海洋关联芽孢杆菌中优化黑色素的生产作为制备用于生物医学应用的碳点的可持续前体
Hadeer Ali,Labiba El-Kohordagui,Ahmed Hussein et al.
Hadeer Ali et al.
Melanin, a multifunctional biopigment with photoprotective, antioxidant, and therapeutic properties, is limited by scarce sustainable sources and poor aqueous solubility. In this study, melanin production from a newly isolated marine-associ...
Biocircular economy-driven bacterial cellulose with large pore size: statistical optimization using Glutamicibacter soli bread waste hydrolysate [0.03%]
基于芽单胞菌面包废弃物水解液的大孔径细菌纤维素的生物循环经济发展：使用Glutamicibacter soli进行统计优化
Fatma Abdul El Hak,Amira A Matrawy,Mohamed S Elnouby et al.
Fatma Abdul El Hak et al.
Bacterial cellulose (BC) is a versatile biopolymer of considerable biotechnological interest, with wide-ranging applications in biomedical, industrial, and engineering fields attributable to its exceptional structural and physicochemical pr...
Heterologous production of tungsten-dependent formate dehydrogenase I from Methylorubrum extorquens in Escherichia coli reveals α-subunit maturation as the major bottleneck [0.03%]
异源生产甲基苏云金芽孢杆菌中的依赖钨的乙酸脱氢酶I揭示α亚基成熟是主要瓶颈
Ngoc Minh Chau Nguyen,Huichang Ryu,Joon Young Park et al.
Ngoc Minh Chau Nguyen et al.
Methylorubrum extorquens formate dehydrogenase I (Me-FDH1) is a tungsten-dependent heterodimeric enzyme with high activity for CO2/formate interconversion, making it an attractive biocatalyst for carbon capture, formate production, and bioe...
Phytochemical characterization and bioactivity evaluation of Artemisia abyssinica methanolic extract as a baseline for bioresource exploration [0.03%]
埃塞俄比亚艾草甲醇提取物的植化分析和生物活性评价以期进行资源开发初探
Abdu Aldarhami,Suliman A Alderhami,Hassen Harzali et al.
Abdu Aldarhami et al.
The growing prevalence of antimicrobial resistance and cancer has intensified interest in natural products as sources of biologically active compounds with potential pharmaceutical relevance. In this study, the phytochemical composition of ...
Grey-box modeling framework for consolidated bioprocessing systems: an endpoint-guided approach [0.03%]
基于目标产物导向的甘薯废弃物 Consolidated Bioprocessing 系统建模与分析
Mark Korang Yeboah,Dirk Söffker
Mark Korang Yeboah
Consolidated bioprocessing (CBP) combines enzyme production, biomass hydrolysis, and fermentation within a single process, but its modeling remains difficult because of biological nonlinearities, feedstock heterogeneity, and limited time-re...
Tri-valorization of methanol in a single bioreactor: co-production of enzyme, chemical, and single-cell protein using engineered Pichia pastoris (Komagataella phaffii) [0.03%]
甲醇单生物反应器的三价化：使用工程毕赤酵母（Komagataella phaffii）共生产酶，化学品和单细胞蛋白
Jiayu Fang,Shuxian Wang,Guoxia Liu et al.
Jiayu Fang et al.
The economic viability of methanol-based biomanufacturing, particularly with green methanol as feedstock, is often limited by the low value of single-product processes. Here, we developed an integrated co-production strategy in the methylot...
Artificial intelligence and automation in enzyme engineering: evolution, advances, and future perspectives [0.03%]
人工智能与自动化在酶工程中的应用：发展、进步和未来展望
Kexin Hao,Jianguang Liu,Hui Tang et al.
Kexin Hao et al.
Natural enzymes often fail to meet industrial demands for catalytic efficiency, stability, and substrate specificity, creating a critical bottleneck in biomanufacturing. This review examines how artificial intelligence (AI) and automation a...
Lignocellulose degradation characteristics and mechanisms of raw and NaOH-pretreated wheat straw by Irpex lacteus QJ: multi-omics analysis [0.03%]
基于QJ优势菌Irpex lacteus降解小麦秸秆多糖的特性及机制研究：多组学分析
Qijun Zhu,Baorui Liu,Zhengrong Dou et al.
Qijun Zhu et al.
The recalcitrant structure of lignocellulose hinders the efficient valorization of wheat straw. White-rot fungi have been extensively studied for their ability to completely degrade lignocellulose, yet the specific mechanisms remain insuffi...
Engineered microorganisms unlock a new era of diterpenoid biomanufacturing: recent advances and future perspectives [0.03%]
工程化微生物解锁倍半萜生物制造新时代：近期进展和未来展望
Yuting Han,Yuanhe Luo,Kaifeng Wang et al.
Yuting Han et al.
Diterpenoids are natural compounds composed of four isoprene units. They possess diverse biological activities and widespread applications in the cosmetics, food additives and pharmaceutical. With the rapid advancement of synthetic biology,...
Solvent-driven modulation of phenolic composition and biofunctional activities of three Mentha aquatica formulations: integrated in vitro and in silico insights [0.03%]
溶剂驱动的三种水薄荷配方的酚类成分和生物功能活性的调节：综合体外和分子对接研究
Meryem Tourabi,Amira Metouekel,Mohamed Jeddi et al.
Meryem Tourabi et al.
The goal of this work was to examine the effect of different solvents (Water, EtOH 70%, and acetone) on the phenolic composition, antioxidant, and antibacterial capacity of Moroccan Mentha aquatica L. leaf extract. To this end, HPLC-ESI-FUL...