Carob pod aqueous extract potentiates cisplatin efficacy and reduces toxicity in experimental hepatocellular carcinoma via mitochondrial and inflammatory pathway modulation [0.03%]
无花果豆的水提取物通过调节线粒体和炎症途径增强实验性肝细胞癌的顺铂疗效并减少毒性
Wael Sobhy Darwish,Abada El Sayed Khadr,Maher Abd El Naby Kamel et al.
Wael Sobhy Darwish et al.
Background: Hepatocellular carcinoma (HCC) is a global health challenge with limited therapeutic options. The effectiveness of conventional medication like cisplatin is often compromised by their severe toxicity. This stu...
Unveiling the therapeutic potential of gut microbiota metabolites for the treatment of renal fibrosis based on network pharmacology study [0.03%]
基于网络药理学研究揭示肠道微生物代谢物治疗肾纤维化的潜在价值
Weiguo Yao,Jinlin Huo,Kun Liu et al.
Weiguo Yao et al.
Background: Renal fibrosis is a progressive injury contributing to renal function deterioration. Mounting evidence has underscored the profound impact of gut microbiota metabolites on host health and disease, yet their un...
Exploration of the mechanism of Xinjiang Rosa laxa Retz.Fruit extract on IgA nephropathy by bioinformatics and machine learning methods [0.03%]
基于生物信息学和机器学习技术探讨新疆野玫瑰果提取物治疗IgA肾病的机制研究
Feng Qianqian,He Yuan,Guo Ying et al.
Feng Qianqian et al.
This study aimed to elucidate the core therapeutic targets and mechanisms of action of rosehip extract (FRLE) in IgA nephropathy (IgAN) by integrating bioinformatics, machine learning, and computational simulation techniques to simultaneous...
Unveiling anti-atherosclerotic targets of Perilla frutescens through a multi-scale computational framework integrating network pharmacology, single-cell analysis, machine learning, and molecular dynamics [0.03%]
基于网络药理学、单细胞分析、机器学习和分子动力学的多层次计算框架揭示紫苏的抗动脉粥样硬化靶点
Chenchen Yang,Jianrong Xing,Mengzhu Wang et al.
Chenchen Yang et al.
Medicinal plants have long served as important sources of therapeutic agents owing to their diverse bioactive constituents and multi-target pharmacological properties. In particular, plant-derived compounds have attracted increasing attenti...
Sustainable carotenoid production using amylaceous agro-industrial byproducts: process efficiency and environmental assessment [0.03%]
以淀粉质农业废弃物为原料的类胡萝卜素可持续生产：工艺效率与环境评估
Thércia Rocha Balbino,Salvador Sánchez-Muñoz,Stephanie Custódio Inácio et al.
Thércia Rocha Balbino et al.
Agro‑industrial brans are abundant residues that can be valorized as low‑cost feedstocks for microbial bioprocesses within a circular‑economy framework. Here, we investigated the use of corn, soybean, rice and wheat bran hydrolysates as ...
A strategy for high-yield lauric acid production in Hermetia illucens fed with pre-fermented sweet potato-based substrate [0.03%]
一种通过预发酵薯类基质喂养赫梅蒂亚虫以高效生产月桂酸的策略
Vivek Manyapu,Yo-Chia Chen
Vivek Manyapu
The intensification of animal farming is associated with increased infectious and zoonotic disease risks. The black soldier fly larvae (BSFL) have antimicrobial activity that could potentially be used to suppress diseases and improve animal...
Recent advances in biomass deconstruction, microbial conversion, artificial intelligence, and carbon capture for sustainable bioenergy [0.03%]
用于可持续生物能源的生物质解构、微生物转化、人工智能和碳捕获方面的最新进展
Vishwajit Kumar,Shikha Mishra,Pratham Joshi et al.
Vishwajit Kumar et al.
The transition from fossil fuels to low-carbon bio-based energy systems is increasingly constrained by the efficiency, scalability, and integration of conversion technologies. Addressing this challenge, this review critically analyzes micro...
Optimized extraction of Pinus taeda knotwood sawmill residues as source of antifungal compounds [0.03%]
作为抗真菌化合物来源的湿地松节木锯末优化提取研究
Rodrigo Coniglio,Juan Martín Rodao,Raquel Alonso et al.
Rodrigo Coniglio et al.
In Uruguay, Pinus taeda is the dominant conifer in industrial plantations, generating large volumes of knot-containing offcuts during processing. These residues are highly enriched in extractives, offering opportunities for valorization wit...
Biomass based carbon quantum dots in sensor applications: a review (2021-2025) [0.03%]
基于生物质的碳量子点在传感器应用中的研究(2021-2025)
Elyor Berdimurodov,Khasan Berdimuradov,Ashish Kumar et al.
Elyor Berdimurodov et al.
The past few years have witnessed an exponential rise in the development of carbon quantum dots (CQDs) derived from natural biomasses, rendering them a green and multifunctional platform for sensor applications. This comprehensive review pr...
Temperature-associated microbial succession and volatile flavor compound dynamics during cigar tobacco leaf fermentation [0.03%]
温度变化下的微生物演替及其在雪茄烟叶发酵过程中风味物质动态变化的影响研究
Tianfei Zheng,Dongfeng Guo,Yaqi Shi et al.
Tianfei Zheng et al.
Temperature is a key factor driving microbial community succession and volatile flavor compound formation during the fermentation of cigar tobacco leaves (CTLs). This study systematically investigated microbial community dynamics, co-occurr...