Stéphanie Pons,Morgane Grosset,Emmanuelle Touze et al.
Stéphanie Pons et al.
Haematological malignancies (HMs) are characterized by profound immune dysregulation, which increases susceptibility to sepsis. This dysregulation arises from the underlying disease and may be exacerbated by treatments. Sepsis itself induce...
Thermocycling: enhancing efficiency of anesthetic reflectors through cyclic heating and cooling-finding the optimal temperature in a bench study [0.03%]
热循环：通过周期性加热和冷却提高麻醉反射器的效率-在实验台研究中寻找最佳温度
Frederic Albrecht,Kathrin Scheffler,David Kellner et al.
Frederic Albrecht et al.
Background: Volatile anesthetics are widely used for sedation in intensive care. Being potent greenhouse gases, their efficient utilization is imperative. We investigated whether the efficiency of anesthetic reflection de...
Comparison of norepinephrine with a combined non-catecholaminergic therapy in a porcine model of refractory cardiac arrest resuscitated with VA-ECMO [0.03%]
与使用VA-ECMO复苏的难治性心脏骤停猪模型中比较去甲肾上腺素和非拟交感胺类联合治疗的效果
Thomas Klein,Vincent Elsensohn,Mathilde Martin-Schouler et al.
Thomas Klein et al.
Introduction: Post-cardiac arrest syndrome (PCAS) under veno-arterial ECMO (VA-ECMO) is frequently complicated by severe vasoplegia and microcirculation failure. Conventional resuscitation relies heavily on catecholamines...
Speed of intravenous fluid on glycocalyx integrity and central blood volume in a porcine septic shock model [0.03%]
静脉输液速度对糖萼完整性和内脏血液容量在猪感染性休克模型中的影响
Yosef Levenbrown,Md Jobayer Hossain,Paul T Fawcett et al.
Yosef Levenbrown et al.
Background: It is unclear whether the rate of intravenous fluid (IVF) administration in sepsis influences glycocalyx breakdown. This study aimed to measure the effect of rapid versus slow fluid bolus in a septic pig model...
Predictive value of ventriculo-arterial coupling for hypotension after induction of anaesthesia: a prospective observational cohort study [0.03%]
心室动脉耦合预测麻醉诱导后低血压的预测价值：前瞻性队列研究
Hong Chinh Le,Chau Bich Ha Tran,Thi Thu Trang Nguyen et al.
Hong Chinh Le et al.
Background: Post-induction hypotension (PIH) is associated with acute perioperative organ injury. We quantified the added value of echocardiographic parameters and ventriculo-arterial coupling (VAC)-related variables for ...
Enhancing large language model clinical support information with machine learning risk and explainability: a feasibility study [0.03%]
利用机器学习风险和可解释性增强大型语言模型临床支持信息的可行性研究
Yu-Chang Yeh,Hsin-Yu Yang,Ching-Tang Chiu et al.
Yu-Chang Yeh et al.
Background: Current machine learning (ML) prediction models offer limited guidance for individualized actionable management. Large language models (LLMs) can transform ML model-predicted risk estimates with Shapley Additi...
Blood-based biomarkers and delirium in critically ill adults in the ICU: a systematic review [0.03%]
重症监护病房成人患者血清生物标志物与谵妄的相关性系统评价
Julie Kathrine Ryberg Sankel,Naia Bech Cranø,Pär Ingemar Johansson et al.
Julie Kathrine Ryberg Sankel et al.
Purpose: Delirium is frequent and associated with increased health expenditures, unfavourable outcomes and increased mortality. Diagnosis currently relies on clinical scales and is often missed. However, blood-based bioma...
Refining an acute respiratory distress syndrome animal model supported by extracorporeal membrane oxygenator: incorporating clinically relevant mechanical ventilation strategy upon development [0.03%]
一种急性肺损伤体外膜氧合动物模型的优化：在其建立过程中采用临床相关的机械通气策略对其进行完善研究
Keibun Liu,Gabriele Fior,Nchafatso Obonyo et al.
Keibun Liu et al.
Background: Acute respiratory distress syndrome (ARDS) requiring veno-venous extracorporeal membrane oxygenation (VV-ECMO) is associated with high mortality. One of the primary challenges in translating preclinical findin...
The effects of lipopolysaccharide-induced endotoxic shock on the intestinal microcirculatory perfusion: an experimental study in pigs [0.03%]
内毒素性休克对肠微循环灌注影响的实验研究（猪）
Moritz Flick,Brennan Schneider,Feras Hatib et al.
Moritz Flick et al.
Background: Impairment of microcirculatory tissue perfusion is a central element of sepsis. Unfortunately, monitoring microcirculatory tissue perfusion to detect microcirculatory dysfunction at the bedside remains challen...
Ricardo Castro,Eduardo Kattan,Jaime Retamal et al.
Ricardo Castro et al.