Ultrasound monitoring of skeletal muscle wasting and relation to nutritional intervention in critically ill patients: MUScleNut study [0.03%]
重症患者骨骼肌消耗的超声监测及其与营养干预的关系：MUScleNut研究
Catarina Rosa Domingues,Simão C Rodeia,Ana Rita Francisco et al.
Catarina Rosa Domingues et al.
Background: Critically ill patients frequently experience profound skeletal muscle (SM) wasting, to which early detection and effective clinical management remain significant challenges. Ultrasonography (US) provides earl...
Impaired serum neutralization and death in Omicron-infected critically ill patients: insights from the French SEVARVIR prospective, multicenter cohort study [0.03%]
关于奥密克戎感染重症患者的血清中和能力受损及死亡情况的法国SEVARVIR前瞻性多中心队列研究报告
Timothée Bruel,Isabelle Staropoli,Pierre Bay et al.
Timothée Bruel et al.
Background: Despite advances in treatment, critically ill COVID-19 patients requiring intensive care unit (ICU) admission continue to comprise a substantial proportion of cases. However, the factors influencing poor progn...
Venous congestion from a vascular waterfall perspective: reframing congestion as a dynamic Starling resistor phenomenon [0.03%]
从血管瀑布的角度看待静脉淤血：将静脉淤血再定义为动态的Starling电阻现象
Ricardo Castro,Eduardo Kattan,Jaime Retamal et al.
Ricardo Castro et al.
The vascular waterfall phenomenon, rooted in Starling resistor principles, describes how blood flow becomes independent of downstream pressure when intraluminal pressure falls below a critical closing pressure (Pcrit). This review first int...
Fluid removal improves muscle performance and weakness in critically ill patients: a pilot study [0.03%]
液体超负荷导致重症患者肌肉功能障碍及虚弱的病因：一项初步研究
Nicolás Arancibia,René López
Nicolás Arancibia
Background: Fluid overload in critically ill patients has been associated with muscle edema, decreased tissue quality, and the development of intensive care unit-acquired weakness (ICU-AW). Continuous renal replacement th...
Knowledge gaps in extracorporeal blood purification: what would be required for its successful application in septic shock? [0.03%]
关于体外血液净化用于感染性休克的知识缺口及其成功应用所需条件
Sascha David,Thomas Rimmelé,Michael Joannidis et al.
Sascha David et al.
Sepsis remains a leading cause of death worldwide, characterized by a dysregulated host response to infection that results in organ dysfunction. Extracorporeal blood purification (EBP) therapies traditionally aim to remove circulating media...
Dynamic changes of natural killer cell immunophenotypes and receptors according to the mortality in the intra-abdominal murine sepsis model [0.03%]
小鼠腹腔内感染模型中NK细胞免疫表型和受体的动态变化及其与死亡率的关系
Sang Hoon Han,Yeon-Mi Hong,Dayeong Kim et al.
Sang Hoon Han et al.
Background: Sepsis is a life-threatening infectious syndrome that lacks targeted pharmacological therapies and poses major challenges in reducing mortality and long-term complications such as disability and frailty. Early...
Hepatic and intestinal microcirculation and pulmonary inflammation in a model of veno-venous extracorporeal membrane oxygenation in the rat [0.03%]
大鼠静脉-静脉体外膜氧合模型中的肝肠微循环及肺部炎症反应
Fabian Edinger,Thomas Zajonz,Nico Mayer et al.
Fabian Edinger et al.
Background: Veno-venous (V-V) extracorporeal membrane oxygenation (ECMO) is widely used in critical care but remains associated with high mortality rates (22-68%). In septic shock, increased pulmonary inflammation and imp...
Effect of low bicarbonate substitution solution on CO2 removal rate in the combined system of extracorporeal CO2 removal and continuous renal replacement therapy [0.03%]
低碳酸氢盐置换液对体外二氧化碳清除与连续性肾脏替代疗法联合系统中CO2清除率的影响
Zhicheng Qian,Rui Zhang,Yuxuan Wang et al.
Zhicheng Qian et al.
Background: The concurrent application of extracorporeal carbon dioxide removal (ECCO₂R) and continuous renal replacement therapy (CRRT) delivers essential respiratory and renal support. However, the use of bicarbonate (...
Reversible impairment of non-invasively assessed mitochondrial oxygen metabolism in the long-term course of patients with sepsis: a prospective monocentric cohort study [0.03%]
长期脓毒症患者非侵入性评估的线粒体氧代谢可逆性损伤：前瞻性单中心队列研究
Anne Standke,Charles Neu,Philipp Baumbach et al.
Anne Standke et al.
Background: Sepsis is characterized by organ dysfunction due to infection, with increasing evidence of mitochondrial dysfunction assessed preclinically and invasively. Protoporphyrin IX-triplet state lifetime technique (P...
Unravelling the complex inflammatory landscape of COVID-19 infection: a pathway to biomarkers identification in infection-associated delirium in the ICU [0.03%]
解析COVID-19感染复杂的炎症图谱：在ICU中与感染相关的谵妄生物标志物鉴定之路
Tristan Born,Matthieu Perreau,Pierre-Paul Axisa et al.
Tristan Born et al.
Background: Delirium is a serious complication in patients with COVID-19-related acute respiratory distress syndrome (ARDS) admitted to the intensive care unit (ICU). Although numerous clinical risk factors have been iden...