Paul A Hilders,Lada Lijović,Martijn Otten et al.
Paul A Hilders et al.
Background: Sepsis is a major cause of morbidity and mortality worldwide, with its heterogeneous and dynamically evolving clinical presentation complicating diagnosis, treatment, and prognosis. The identification of clini...
The impact of metabolic syndrome on regional ventilation and perfusion in ARDS: an observational cohort study using electrical impedance tomography [0.03%]
代谢综合征对ARDS局部通气与灌注的影响：一项采用电阻抗断层扫描的队列观察研究
Timothy G Gaulton,Marcus Victor,Glasiele Alcala et al.
Timothy G Gaulton et al.
Background: Acute Respiratory Distress Syndrome (ARDS) is characterized by severe hypoxemia from heterogeneous impairments in regional ventilation and perfusion. Metabolic syndrome, a combination of central obesity, insul...
Clinical practice in using corticosteroids and adjunctive sepsis therapies at the bedside among European ICUs: an ESICM-endorsed survey [0.03%]
欧洲ICU皮质类固醇和抗感染药物临床应用的调查研究
Sascha David,Marc Leone,Massimo Girardis et al.
Sascha David et al.
Background: Sepsis and septic shock remain major causes of morbidity and mortality worldwide, and management is largely based on source control, antimicrobial therapy, and supportive care. Despite limited high-quality evi...
Endotoxemia and its association with immune and coagulopathy responses in severe community-acquired pneumonia and COVID-19 [0.03%]
内毒素血症与社区获得性肺炎和新型冠状病毒肺炎重症免疫及凝血反应的关系
Mathieu Blot,Amadou-Khalilou Sow,David Masson et al.
Mathieu Blot et al.
Background: Acute community-acquired pneumonia (CAP) is a leading cause of infection-related mortality worldwide. Endotoxemia, characterized by elevated plasma lipopolysaccharide (LPS), is a key driver of inflammation and...
Admission systemic immune-inflammatory index predicts long-term mortality in patients with acute ischemic stroke: a retrospective analysis of the MIMIC-III database [0.03%]
基于MIMIC-III数据库的急性缺血性卒中患者长期预后的影响因素分析
Xiao Su,Xiuqing Tong,Ning Li et al.
Xiao Su et al.
Background: The Aggregate Index of Systemic Inflammation (AISI) is a novel index based on platelets, neutrophils, and lymphocytes associated with the prognosis of patients with cancer and infectious diseases. However, its...
Milrinone and levosimendan improve microvascular perfusion in septic rats: a randomized, placebo-controlled trial [0.03%]
米力农和左西孟丹可改善脓毒症大鼠的微血管灌注：一项随机、安慰剂对照试验
Carsten Marcus,Stefan Hof,Alena Gesing et al.
Carsten Marcus et al.
Background: Microcirculatory dysfunction is a key pathophysiological feature of sepsis and contributes to organ failure and mortality. In the gastrointestinal tract, impaired barrier function due to microcirculatory injur...
Jon-Emile S Kenny,Per Werner Moller
Jon-Emile S Kenny
Animal models of critical illness in the Asia-Pacific region: current practices, shared challenges, and future directions [0.03%]
亚太地区危重病动物模型的研究：现有方法、共同挑战及未来方向
Yoshihisa Fujinami,Shuangqing Liu,Gianluigi Li Bassi et al.
Yoshihisa Fujinami et al.
Animal models of critical illness span diverse species and experimental approaches, reflecting the biological complexity of severe disease states while being constrained by animal welfare requirements and country-specific regulatory, infras...
Simple and reliable method for predicting extracorporeal membrane oxygenation flow rates and circuit pressures [0.03%]
一种预测体外膜氧合流量和电路压力的简便且可靠的方法
Kazuhiro Takahashi,Seiga Takahashi,Yusuke Takei et al.
Kazuhiro Takahashi et al.
Background: Venovenous extracorporeal membrane oxygenation (ECMO) is essential for patients with severe respiratory failure who do not respond to conventional mechanical ventilation. Adequate ECMO flow and safe circuit pr...
Ventilation-perfusion effects of negative-pressure ventilation: insights from an experimental rat model [0.03%]
负压通气的换气功能效应：实验性大鼠模型的观察结果
Gergely H Fodor,Ferenc Peták,Petra Somogyi et al.
Gergely H Fodor et al.
Background: Mechanical ventilation typically utilizes positive-pressure ventilation (PPV), which fundamentally differs from physiological pressure conditions. In contrast, negative-pressure ventilation (NPV) more closely ...