Matters arising: personalised viscoelastometry-guided systemic thrombolysis for high- and intermediate-high-risk acute pulmonary embolism in the ICU: a single-centre randomised controlled interventional feasibility trial [0.03%]
ICU中高危和极高危急性肺栓塞个体化血流变图检查指导全身溶栓治疗的事后研究：一项中心随机对照干预可行性试验
Maajid Mohi Ud Din Malik,Rajesh Prasad Jayaswal
Maajid Mohi Ud Din Malik
Digital performance testing reveals how redesigned return cannulas can enhance VV-ECMO performance [0.03%]
数字性能测试揭示了如何通过改进返回灌注管来提升静脉-动脉体外膜肺氧合的性能
Beata Ondrusova,Argyrios Petras,Johannes Szasz et al.
Beata Ondrusova et al.
Background: Veno-venous extracorporeal membrane oxygenation (VV-ECMO) provides life support for patients with severe respiratory failure by oxygenating blood when the lungs are impaired. Standard VV-ECMO uses two cannulas...
Pre-discharge neutrophil:lymphocyte ratio and lymphopenia are associated with post-hospital long-term outcomes among survivors of critical illness [0.03%]
重症监护幸存者出院前的中性粒细胞与淋巴细胞比率和淋巴细胞减少与医院长期预后相关性研究
Lucas L Marinho,John C Marshall,Danielle Jeong et al.
Lucas L Marinho et al.
Mass cytometry reveals complex neutrophil heterogeneity in patients with severe sepsis [0.03%]
高通量质谱流式细胞术发现严重脓毒症患者复杂的中性粒细胞异质性
Patricia D A Lima,Christina Yu,Miranda Hunt et al.
Patricia D A Lima et al.
Rationale: Sepsis is a state of life-threatening organ dysfunction in the setting of infection. It is biologically heterogeneous, as evidenced by whole blood transcriptomic analyses that reveal distinct molecular subtypes...
Prospective and external evaluation of an AI model for continuous and early prediction of moderate and severe AKI in critically ill patients [0.03%]
前瞻性及外部评估人工智能模型在重症患者中持续且早期预测中重度急性肾损伤的能力
Francesca Alfieri,Simone Zappalà,Alessandro Bacci et al.
Francesca Alfieri et al.
Background: Acute kidney injury (AKI) is a major complication in critically ill patients, burdening both patients and healthcare systems. We previously introduced an AI-based model for early and continuous prediction of I...
Impact of noradrenaline, adrenergic receptors, and radical formation on cardiac mitochondria in resuscitated swine [0.03%]
去甲肾上腺素、肾上腺受体及自由基形成对复苏猪心脏线粒体的影响
Nadja Abele,Tamara Merz,Fabian Zink et al.
Nadja Abele et al.
Background: Equivocal data exist on whether noradrenaline during resuscitation from circulatory shock affects tissue mitochondrial respiration. Therefore, we examined the relation between myocardial mitochondrial respirat...
Acute brain dysfunction clusters in COVID-19: a pilot machine learning-based analysis of the COVID-D cohort [0.03%]
基于机器学习的COVID-D队列中新冠肺炎相关急性脑功能障碍类型的研究试点项目
Nekane Romero-García,Víctor Montosa-I-Micó,David Fernández-Narro et al.
Nekane Romero-García et al.
Purpose: While acute brain dysfunction (ABD, i.e., delirium and coma) is associated with significantly increased morbidity in critically ill patients, it presents with great heterogeneity that poses a challenge for manage...
Proteomic signatures of renal recovery from acute kidney injury-a translational study in critically ill postoperative patients [0.03%]
急性肾损伤后肾功能恢复的蛋白质组标志物——重症术后患者的转化研究
Thilo von Groote,Moritz J Mertes,Hendrik Booke et al.
Thilo von Groote et al.
Background: Acute kidney injury (AKI) is a common complication in critically ill patients and frequently progresses to persistent renal dysfunction. However, mechanisms underlying renal recovery versus persistent dysfunct...
Chest compression synchronized ventilation versus chest compression superimposed by sustained inflation in asphyxiated newborn piglets: a randomized animal trial [0.03%]
胸外按压与同步通气相比，外加持续正压通气在新生儿窒息仔猪模型中的效果：一项随机动物试验
Raza Hyderi,Shrieya Praveen,Megan O&#x;Reilly et al.
Raza Hyderi et al.
Background: Guidelines on neonatal resuscitation recommend 90 chest compressions (CCs) and 30 ventilations (3:1 C:V) per minute in newborns. We have described an alternative resuscitation strategy where CCs are superimpos...
Danielle R Lavage,Lauren N Ward,Derek C Angus et al.
Danielle R Lavage et al.