Timing of hypothermic temperature control does not affect neurological outcomes after cardiac arrest: a systematic review and meta-analysis [0.03%]
心脏骤停后诱导低温治疗的时机对神经预后无影响——系统评价和meta分析
Krisztina Csőke-Kabai,Zsolt Molnár,László Zubek et al.
Krisztina Csőke-Kabai et al.
Out-of-hospital cardiac arrest is associated with a low rate of favourable neurological recovery, estimated at 8%. Lowering the cerebral metabolic rate with hypothermic temperature control is hypothesized to improve this outcome. Given the ...
Source control within 12 h attenuates lung injury and systemic bacterial burden in a rat model of polymicrobial abdominal sepsis (cecal ligation and puncture) [0.03%]
源头控制在12小时内可减轻多微生物性腹腔脓毒症模型中肺损伤和全身细菌负荷
Maria Luisa Martinez,Eva Torrents,Marta Camprubí-Rimblas et al.
Maria Luisa Martinez et al.
Background: Early and adequate source control (SC) is a cornerstone of sepsis management, yet experimental data linking delays in SC to bacterial dissemination and remote organ injury remain limited. We aimed to determine...
In-depth tube assessment by ultrasound: double twist sign to evaluate endotracheal tube depth-results of a cadaver diagnostic accuracy study [0.03%]
超声深入气管评估：双扭征评估气管导管深度的结果——一项法医诊断准确性研究
Jorge Ernesto Lopez Matta,Marissa Ginette Vive,Carlos Vsevolod Elzo Kraemer et al.
Jorge Ernesto Lopez Matta et al.
Purpose: An adequate endotracheal tube depth is crucial for airway management and effective mechanical ventilation, as both too deep and superficial tube placement can be harmful to the patient. The aim of this study was ...
Leashing heterogeneous sepsis with phenotype-informed decision support modeling [0.03%]
基于表型的决策支持模型在异质性脓毒症中的应用
Joo Heung Yoon,Faraaz Ali Shah
Joo Heung Yoon
Experimental robustness and reproducibility of the murine cecal ligation and puncture sepsis model [0.03%]
结肠穿孔模型的实验可靠性和重复性研究
Korbinian Felix Schreyer,Julia Stettmer,Li Cheng Wu et al.
Korbinian Felix Schreyer et al.
Background: Sepsis, a dysregulated host response to infection leading to organ failure, remains a leading cause of death worldwide, reflecting the failure to translate preclinical findings into clinical therapies. This tr...
Dynamics of platelet activation in cold-stored low-titer group O whole blood over 8 days: insights relative to standard platelet concentrates [0.03%]
冷存O型低滴度全血血小板活化动力学变化（长达8天）及其与标准血小板浓缩制剂的对比研究
Fabrice Cognasse,Karine Desseux,Véronique Artero et al.
Fabrice Cognasse et al.
Background: Low-titer group O whole blood (LTOWB) is increasingly used for hemorrhagic resuscitation in trauma and critical care, but the phenotype of platelets maintained within refrigerated LTOWB remains incompletely ch...
Machine learning models predicting extubation success in mechanically ventilated patients: a systematic review and meta-analysis [0.03%]
预测机械通气患者拔管成功的机器学习模型：系统回顾和meta分析
Péter Bakos,Bence Szabó,Dávid Laczkó et al.
Péter Bakos et al.
Background: Optimal timing of extubation in mechanically ventilated patients remains a major challenge in intensive care. Machine learning (ML) models have been increasingly proposed to support clinical decision-making, y...
Hepatic and intestinal microcirculation and pulmonary inflammation in a model of veno-arterial extracorporeal membrane oxygenation in the rat [0.03%]
大鼠经皮静脉动脉体外膜式氧合模型中的肝脏和肠道微循环及肺部炎症反应
Fabian Edinger,Thomas Zajonz,Nico Mayer et al.
Fabian Edinger et al.
Background: Due to peripheral cannulation, veno-arterial (V-A) extracorporeal membrane oxygenation (ECMO) therapy is increasingly used outside the cardiac operation room. Despite significant efforts toward improving thera...
Decoy receptor 3 as a diagnostic marker for sepsis: a meta-analysis [0.03%]
decoy受体3作为诊断脓毒症的标记物的.meta.分析
Xiao-Ke Zhang,Rong-Yue Gao,Yu-Zhen Han et al.
Xiao-Ke Zhang et al.
Objective: Sepsis is a syndrome of systemic inflammatory reaction caused by a severe infection, leading to multiorgan damage and a high mortality rate. In recent years, several studies have shown that decoy receptor 3 (Dc...
Christopher Lai,Talal Shaikhain,Sheldon Magder
Christopher Lai
Background: Dobutamine exerts its pharmacological effects by stimulating α1-, β1-, and β2-adrenergic receptors. Activation of these receptors increase both the force of cardiac contraction (inotropy) and heart rate (ch...