Prospective and external evaluation of an AI model for continuous and early prediction of moderate and severe AKI in critically ill patients [0.03%]
前瞻性及外部评估人工智能模型在重症患者中持续且早期预测中重度急性肾损伤的能力
Francesca Alfieri,Simone Zappalà,Alessandro Bacci et al.
Francesca Alfieri et al.
Background: Acute kidney injury (AKI) is a major complication in critically ill patients, burdening both patients and healthcare systems. We previously introduced an AI-based model for early and continuous prediction of I...
Impact of noradrenaline, adrenergic receptors, and radical formation on cardiac mitochondria in resuscitated swine [0.03%]
去甲肾上腺素、肾上腺受体及自由基形成对复苏猪心脏线粒体的影响
Nadja Abele,Tamara Merz,Fabian Zink et al.
Nadja Abele et al.
Background: Equivocal data exist on whether noradrenaline during resuscitation from circulatory shock affects tissue mitochondrial respiration. Therefore, we examined the relation between myocardial mitochondrial respirat...
Acute brain dysfunction clusters in COVID-19: a pilot machine learning-based analysis of the COVID-D cohort [0.03%]
基于机器学习的COVID-D队列中新冠肺炎相关急性脑功能障碍类型的研究试点项目
Nekane Romero-García,Víctor Montosa-I-Micó,David Fernández-Narro et al.
Nekane Romero-García et al.
Purpose: While acute brain dysfunction (ABD, i.e., delirium and coma) is associated with significantly increased morbidity in critically ill patients, it presents with great heterogeneity that poses a challenge for manage...
Proteomic signatures of renal recovery from acute kidney injury-a translational study in critically ill postoperative patients [0.03%]
急性肾损伤后肾功能恢复的蛋白质组标志物——重症术后患者的转化研究
Thilo von Groote,Moritz J Mertes,Hendrik Booke et al.
Thilo von Groote et al.
Background: Acute kidney injury (AKI) is a common complication in critically ill patients and frequently progresses to persistent renal dysfunction. However, mechanisms underlying renal recovery versus persistent dysfunct...
Chest compression synchronized ventilation versus chest compression superimposed by sustained inflation in asphyxiated newborn piglets: a randomized animal trial [0.03%]
胸外按压与同步通气相比，外加持续正压通气在新生儿窒息仔猪模型中的效果：一项随机动物试验
Raza Hyderi,Shrieya Praveen,Megan O&#x;Reilly et al.
Raza Hyderi et al.
Background: Guidelines on neonatal resuscitation recommend 90 chest compressions (CCs) and 30 ventilations (3:1 C:V) per minute in newborns. We have described an alternative resuscitation strategy where CCs are superimpos...
Danielle R Lavage,Lauren N Ward,Derek C Angus et al.
Danielle R Lavage et al.
Innovation in sepsis trials: rethinking endpoints, statistics and patient stratification [0.03%]
创新的脓毒症试验：重新思考终点、统计和患者分层
Sascha David,Marc Leone,Massimo Girardis et al.
Sascha David et al.
Despite extensive research, effective causal therapies for sepsis remain elusive, highlighting a persistent translational gap between biological understanding and clinical outcomes. Traditional randomised clinical trials (RCTs) have largely...
Evaluation of plasma calprotectin as a marker for infection in various clinical settings: a prospective observational study [0.03%]
评估血浆Calprotectin在不同临床环境中的感染标志物价值：一项前瞻性观察研究
Tobias Zimmermann,Timothy Arthur Chandos Snow,Pedro Lopez-Ayala et al.
Tobias Zimmermann et al.
Background: Reliably distinguishing infection from sterile inflammation is a major clinical challenge. Uncertainty can lead to unnecessary courses of antibiotics, fueling antimicrobial resistance and adverse effects. Calp...
Identification of physiological clusters in acute hypoxemic respiratory failure patients undergoing non-invasive respiratory support using EIT-based t-SNE and spectral clustering [0.03%]
基于EIT的t-SNE和谱系聚类在急性低氧性呼吸衰竭非侵入性呼吸支持患者生理分类中的应用识别
Gaetano Scaramuzzo,Valentina Bellini,Matteo Trevisani et al.
Gaetano Scaramuzzo et al.
Purpose: Identifying physiological clusters in acute hypoxemic respiratory failure (AHRF) may help to personalize non-invasive respiratory support (NIRS). Electrical impedance tomography (EIT) provides real-time, regional...
Impact of air pollution on exacerbations of respiratory and cardiovascular diseases for the intensivist: a narrative review [0.03%]
空气污染对呼吸和心血管系统疾病加重的影响：一篇针对重症监护医生的综述文章
Alexandre Gaudet,Charlotte Lacombe,Gaetan Piga et al.
Alexandre Gaudet et al.
Air pollution is a major global health threat, yet its specific impact on critically ill patients remains underexplored. While the link between air pollution and respiratory and cardiovascular events is well-documented, its contribution to ...