Establishment of a neonatal rat model of sequential hyperoxic hypoxia to recapitulate clinical progression of bronchopulmonary dysplasia-associated pulmonary hypertension [0.03%]
建立连续过氧化-低氧暴露的新生大鼠模型以模拟支气管肺发育不良相关性肺高压的临床进程
Dan Wang,Siqi Hu,Jingke Cao et al.
Dan Wang et al.
Background: Bronchopulmonary dysplasia-associated pulmonary hypertension (BPD-PH) seriously threatens the lives of preterm infants. The absence of animal models that can simulate its progression from early hyperoxic lung ...
Timing of inotropic support is associated with mortality in patients with acute decompensated heart failure-associated cardiogenic shock [0.03%]
正性肌力支持的时机与急性心衰相关性心源性休克患者的死亡率的关系
John C Greenwood,Charith Ratnayake,Moizza Shabbir et al.
John C Greenwood et al.
Background: Inotropic support is often used to improve hemodynamics and organ perfusion in patients with advanced heart failure-related cardiogenic shock (ADHF-CS). We aimed to evaluate the effect of inotrope timing on pa...
Lung injury promoted by strong inspiratory efforts and breath stacking: impact of ventilation mode [0.03%]
由强力吸气努力和呼吸堆积所致的肺损伤：机械通气模式的影响
Yasuhiro Norisue,Sunao Usami,Yukie Ito et al.
Yasuhiro Norisue et al.
Background: Breath stacking, particularly double triggering, is a common patient-ventilator asynchrony during strong inspiratory effort. It can cause excessive tidal volumes and high transpulmonary pressures, contributing...
The ADVanced Organ Support (ADVOS) hemodialysis system balances blood pH within 24 h in patients with multiple organ failure and hypercapnic acidosis [0.03%]
先进的器官支持系统（ADVOS）血液透析系统可在24小时内平衡多器官衰竭和高碳酸血症酸中毒患者的血液PH值
Miriam Dibos,Aritz Perez Ruiz de Garibay,Ulrich Mayr et al.
Miriam Dibos et al.
Background: Severe hypercapnia, especially when associated with acidosis, should be avoided or actively managed, as it is an independent risk factor in critically ill patients. The ADVOS multi hemodialysis system offers t...
Transesophageal lung ultrasound score is associated with arterial oxygenation and clinical outcomes in mechanically ventilated critically ill patients [0.03%]
经食道肺超声评分与机械通气危重症患者的动脉血氧合及临床结局相关性研究
Daiyin Cao,Wenliang Song,Weining Zhu et al.
Daiyin Cao et al.
Background: Transesophageal lung ultrasound (TELUS) has emerged as a novel modality that utilizes the esophageal acoustic window to obtain high-resolution images of posterior lung regions. However, its quantitative assess...
Explainable AI identifies key biomarkers for acute kidney injury prediction in the ICU [0.03%]
可解释的人工智能识别急性肾损伤的生物标志物以预测重症监护室患者的急性肾损伤
Hazem Koozi,Jonas Engström,Hans Friberg et al.
Hazem Koozi et al.
Background: Early identification of acute kidney injury (AKI) in the intensive care unit (ICU) remains challenging. We aimed to identify key predictors of new-onset AKI within 48 h after ICU admission and renal replacemen...
Hypothermia after Cardiac Arrest in Large Animals (HACA-LA): a randomized controlled experimental study [0.03%]
大型动物心脏骤停后低温治疗(HACA-LA):一项随机对照实验研究
Olof Persson,Anna Valerianova,Leos Tejkl et al.
Olof Persson et al.
Background: Induced hypothermia after cardiac arrest is neuroprotective in several animal models of cardiac arrest, but few high-quality studies have been conducted in larger animals. Recent clinical trials have questione...
Differential effect on acute pulmonary perfusion according to mechanical support in acute myocardial infarction cardiogenic shock: an acute animal model [0.03%]
急性心肌梗死心脏源性休克机械支持对急性肺灌注影响的差异：急性动物模型研究
Stéphane Manzo-Silberman,Bart Meyns,Guillaume Lebreton
Stéphane Manzo-Silberman
Correction: Development and validation of a machine learning model for early prediction of intensive care unit acquired weakness [0.03%]
纠正：重症监护室获得性肌无力早期预测机器学习模型的开发和验证
Felipe Kenji Nakano,Nathalie Van Aerde,Gregoire Coppens et al.
Felipe Kenji Nakano et al.
Published Erratum
Intensive care medicine experimental. 2025 Oct 20;13(1):103. DOI:10.1186/s40635-025-00817-w 2025
Combined mechanical ventilatory and mechanical circulatory support aids pulmonary vascular state in cardiogenic shock [0.03%]
机械通气和机械循环支持有助于心源性休克患者的肺血管状态
Kimberly K Lamberti,Elazer R Edelman,Steven P Keller
Kimberly K Lamberti
Background: Percutaneous ventricular assist devices (pVADs) support patients in circulatory failure and increasingly concomitant respiratory failure. The presence of co-existent lung disease creates a management challenge...