4-Phenylbutyric acid extends the gold time of uncontrolled hemorrhagic shock at high altitude by alleviating vital organ injury [0.03%]
4-苯基丁酸钠通过缓解重要器官损伤延长高原难治性失血性休克的黄金救治时间
Jie Zhang,Xiao-Yong Peng,Yue Wu et al.
Jie Zhang et al.
Background: Uncontrolled hemorrhagic shock (UHS) is prevalent in military operations, disaster relief, and traffic accidents at high altitudes. Due to reduced tolerance to resuscitation fluids and prolonged evacuation tim...
The association of arterial partial oxygen pressure with mortality in patients with severe acute pancreatitis: a retrospective cohort study [0.03%]
急性重度胰腺炎患者动脉分压与病死率的关联性研究：回顾性队列研究
Yiji Chen,Jianhua Wan,Wenqing Shu et al.
Yiji Chen et al.
Background: Patients with severe acute pancreatitis (SAP) frequently develop hypoxic acute respiratory failure (AHRF), with a mortality rate as high as 37%. However, the optimal partial pressure of oxygen (PaO2) for SAP p...
Prediction and prevention of ventilation impairments during bronchoscopy [0.03%]
支气管镜检查过程中通气功能障碍的预测和预防
Ben Fabry,Navid Bonakdar,Christian Kuster et al.
Ben Fabry et al.
Background: Bronchoscopy in ventilated patients narrows the endotracheal tube lumen and increases resistance, which can lead to hypoventilation and intrinsic PEEP build-up. These ventilation impairments depend on the geom...
Effects of perioperative dexmedetomidine on renal vascular function and renovascular histopathology in ovine cardiopulmonary bypass [0.03%]
瑞米兌明对羊心脏肺阻断术周围血管功能和肾血管组织病理学的影响
Ashenafi H Betrie,Alemayehu H Jufar,Roger G Evans et al.
Ashenafi H Betrie et al.
Background: Cardiopulmonary bypass (CPB) is integral to the conduct of cardiac surgery but is associated with postoperative acute kidney injury (AKI). Dexmedetomidine, an α₂-adrenoceptor agonist with anti-inflammatory a...
The role of transcranial Doppler in predicting the incidence and prognosis of sepsis-associated encephalopathy [0.03%]
经颅多普勒在预测脓毒症相关性脑病发生及预后中的作用
Hanady Mohammed Elfeky,Mohamed Basyouni Helal,Reham Naser Sherif et al.
Hanady Mohammed Elfeky et al.
Background: Sepsis-associated encephalopathy (SAE) is a common complication of sepsis, contributing to poor outcomes and increased mortality. Early detection remains challenging due to the absence of observable direct bra...
Effects of therapeutic hypothermia on brain function in a refractory cardiac arrest model treated with extracorporeal cardiopulmonary resuscitation [0.03%]
体外心肺复苏术后难治性心脏骤停模型中目标温度管理对脑功能影响的实验研究
Anthony Moreau,Fuhong Su,Lorenzo Ferlini et al.
Anthony Moreau et al.
Background: Cardiac arrest (CA) remains a leading cause of mortality and long-term neurological disability. In cases of refractory CA, extracorporeal cardiopulmonary resuscitation (ECPR) may be implemented as a salvage th...
Elina Nazarian,Jante S Sinnige,Lieuwe D J Bos et al.
Elina Nazarian et al.
Lung ultrasound has become an indispensable tool in the management of acute respiratory failure, offering real-time, radiation-free bedside imaging. Its portability, repeatability, and high sensitivity for detecting pulmonary abnormalities ...
Assessment of V/Q mismatch during pressure support ventilation with electrical impedance tomography: a prospective physiological study [0.03%]
应用电气阻抗断层扫描技术评估压力支持通气时的血流灌注-通气不匹配现象：一项前瞻性生理学研究
Mariachiara Ippolito,Giacomo Grasselli,Antonino Giarratano et al.
Mariachiara Ippolito et al.
Introduction: Spontaneous breathing may have both protective and negative effects in patients with ARDS, according to the severity of lung injury. Scarce evidence is available for physicians to safely guide the transition...
Kinetics of molecular patterns captured by mannose-binding lectin in septic shock correlate with clinical outcome: a monocentric prospective observational study [0.03%]
由甘露聚糖结合凝集素捕获的分子图谱在休克中的动力学与临床结果相关：一项单中心前瞻性观察研究
Alain Bicart-See,Fanny Vardon,Stephanie Ruiz et al.
Alain Bicart-See et al.
Background: Various serum biomarkers and scoring systems are currently employed to manage septic critically ill patients. However, a paucity of biomarker evidence facilitates sepsis identification or prognosis. Mannose-bi...
Veno-arterial CO2 content gradient and veno-arterial CO2 to arterial-venous O2 content ratio for outcome prediction after pediatric cardiac surgery: a prospective study [0.03%]
儿童心脏手术后预后的预测：一项前瞻性研究中的静脉-动脉二氧化碳含量梯度和静脉-动脉二氧化碳与动静脉氧含量比值的研究
Vladimir L Cousin,Raphael Joye,Tomasz Nalecz et al.
Vladimir L Cousin et al.
Introduction: CO2-derived variables, veno-arterial CO2 content gradient (ΔCCO2) and the ratio of ΔCCO2 with arterio-venous oxygen difference (AV-DO2) (ΔCCO2/AV-DO2), may have a potential role as indicators of low cardi...