The complexity of interactions between female sex hormones and Chlamydia trachomatis infections [0.03%]
女性性激素与沙眼衣原体感染之间相互作用的复杂性
Amy Berry,Jennifer V Hall
Amy Berry
Purpose of review: This review focuses specifically on the mechanisms by which female sex hormones, estrogen and progesterone, affect Chlamydia trachomatis infections in vivo and in vitro. ...
Bernardo A Mainou
Bernardo A Mainou
Purpose of review: the ability of viruses to infect host cells is dependent on several factors including the availability of cell-surface receptors, antiviral state of cells, and presence of host factors needed for viral ...
Respiratory epithelial cells as master communicators during viral infections [0.03%]
呼吸道上皮细胞在病毒感染期间作为主要通讯者的角色
Tanya A Miura
Tanya A Miura
Purpose of review: Communication by epithelial cells during respiratory viral infections is critical in orchestrating effective anti-viral responses but also can lead to excessive inflammation. This review will evaluate s...
The role of neutrophils in host defense against invasive fungal infections [0.03%]
中性粒细胞在宿主防御侵袭性真菌感染中的作用
Jigar V Desai,Michail S Lionakis
Jigar V Desai
Purpose of review: Invasive fungal infections caused by the commensal yeast Candida and the ubiquitous, inhaled mold Aspergillus have emerged as major causes of morbidity and mortality in critically ill and immunosuppress...
Imtiaz A Khan,Charlotte Ouellette,Keer Chen et al.
Imtiaz A Khan et al.
Toxoplasma gondii infection induces a strong immunity in the host. Although the response is manifested by innate response during early infection, adaptive immunity is critical for long-term protection. Amongst the adaptive immune response C...
Tissue Destruction Caused by Entamoeba histolytica Parasite : Cell Death, Inflammation, Invasion, and the Gut Microbiome [0.03%]
溶组织内阿米巴原虫引起的组织损伤：细胞死亡、炎症、入侵和肠道菌群的影响
Swagata Ghosh,Jay Padalia,Shannon Moonah
Swagata Ghosh
Purpose of review: Entamoeba histolytica is a protozoan parasite that causes amebiasis, which remains a significant cause of morbidity and mortality worldwide. E. histolytica causes tissue destruction which leads to clini...
Transcriptional and post-transcriptional regulation of viral gene expression in the gamma-herpesvirus Kaposi's sarcoma-associated herpesvirus [0.03%]
卡波西肉瘤疱疹病毒的基因表达的转录及转录后的调节机制研究
Matthew Butnaru,Marta M Gaglia
Matthew Butnaru
Purpose of review: Kaposi's sarcoma-associated herpesvirus (KSHV), the etiological agent of the AIDS-associated tumor Kaposi's sarcoma, is a complex virus that expresses ~90 proteins in a regulated temporal cascade during...
Ashley Zani,Jacob S Yount
Ashley Zani
Purpose of review: Interferon-induced transmembrane protein 3 (IFITM3) is a cellular restriction factor that blocks fusion between virus and host membranes. Here, we provide an introduction to IFITM3 and the biochemical r...
Alexis Garcia,Sandeep Vellanki,Soo Chan Lee
Alexis Garcia
Purpose of review: Mucormycosis is an emerging opportunistic fungal infection whose causative agents are found within the Mucorales family. A recent increase in immunocompromised cohorts with solid organ transplants, diab...
Adaptation of Candida albicans during gastrointestinal tract colonization [0.03%]
白色念珠菌在肠道定植过程中的适应性变迁研究
Animesh A Mishra,Andrew Y Koh
Animesh A Mishra
Purpose of review: Colonization of the gastrointestinal (GI) tract with Candida albicans (CA), the most common human fungal pathogen, is the first step towards the development of invasive infection. Yet the fungal virulen...