Steven J Murdock,Justine R Bersonda,J Craig Forrest et al.
Steven J Murdock et al.
Purpose of review: This review summarizes results from recent studies that shed light on viral and cellular mechanisms that contribute to latency and persistence of Kaposi sarcoma-associated herpesvirus (KSHV). We discuss...
Asia S Wildeman,Valeria C Culotta
Asia S Wildeman
Purpose of review: Copper, zinc, iron and manganese are essential micronutrients for all living organisms. Microbial pathogens must acquire these elements from their host. Through a process termed nutritional immunity, an...
Long-Read Sequencing for the Rapid Response to Infectious Diseases Outbreaks [0.03%]
基于长读测序的传染病疫情快速应对策略
Josephine B Oehler,Kaitlin Burns,Jeffrey Warner et al.
Josephine B Oehler et al.
Purpose of review: Long-read sequencing (LRS) has revolutionized pathogen surveillance by enabling real-time, high-fidelity genomic analysis critical for outbreak response. This review synthesizes recent breakthroughs in ...
Bridging Ecology and Microbiomes: Applying Ecological Theories in Host-associated Microbial Ecosystems [0.03%]
生态学与微生物组：在宿主相关微生态系统中应用生态理论
Clara Flores,Sophie Millard,Anna M Seekatz
Clara Flores
Purpose of review: This review explores the application of classical ecological theory to host-associated microbiomes during initial colonization, maintenance, and recovery. We discuss unique challenges of applying these ...
Uxua Modrego Lopez,Md Mehedi Hasan,Brandon Havranek et al.
Uxua Modrego Lopez et al.
Purpose of the review: SARS-CoV-2 undergoes genetic mutations like many other viruses. Some mutations lead to the emergence of new Variants of Concern (VOCs), affecting transmissibility, illness severity, and the effectiv...
Integrating Genomic Data with the Development of CRISPR-Based Point-of-Care-Testing for Bacterial Infections [0.03%]
整合基因组数据与基于CRISPR的细菌感染即时检测(Point-of-Care-Testing)开发
Thanyapat Wanitchanon,Claire Chewapreecha,Chayasith Uttamapinant
Thanyapat Wanitchanon
Purpose of review: Bacterial infections and antibiotic resistance contribute to global mortality. Despite many infections being preventable and treatable, the lack of reliable and accessible diagnostic tools exacerbates t...
Sui Ting Hui,Hugh Gifford,Johanna Rhodes
Sui Ting Hui
Purpose of review: Over recent decades, the number of outbreaks caused by fungi has increased for humans, plants (including important crop species) and animals. Yet this problem is compounded by emerging antifungal drug r...
Intimate Relationship Between Stress and Human Alpha‑Herpes Virus 1 (HSV‑1) Reactivation from Latency [0.03%]
应激与人类α-疱疹病毒1型（HSV-1）从潜伏状态再活化的密切关系
Clinton Jones
Clinton Jones
Purpose of review: Numerous studies concluded stress (acute, episodic acute, or chronic) increases the incidence of human alpha-herpes virus 1 (HSV-1) reactivation from latency in neurons. This review will summarize how s...
Modeling and Remodeling the Cell: How Digital Twins and HCMV Can Elucidate the Complex Interactions of Viral Latency, Epigenetic Regulation, and Immune Responses [0.03%]
细胞的建模与再建模：数字孪生和HCMV如何阐明病毒潜伏、表观遗传调控和免疫反应的复杂相互作用
Hana McMahon-Cole,Alicia Johnson,Sara Sadat Aghamiri et al.
Hana McMahon-Cole et al.
Purpose of review: Human cytomegalovirus (HCMV), while asymptomatic in most, causes significant complications during fetal development, following transplant or in immunosuppressed individuals. The host-virus interactions ...
Conserved and Divergent Features of pH Sensing in Major Fungal Pathogens [0.03%]
主要真菌病原体中pH感应的保守性和差异性特征
Shadab Farhadi Cheshmeh Morvari,Bethany L McCann,Elaine M Bignell
Shadab Farhadi Cheshmeh Morvari
Purpose of review: For human fungal pathogens, sensory perception of extracellular pH is essential for colonisation of mammalian tissues and immune evasion. The molecular complexes that perceive and transmit the fungal pH...