Viral genetic diversity and its potential contributions to the development and progression of neonatal herpes simplex virus (HSV) disease [0.03%]
病毒的遗传多样性及其对新生儿单纯疱疹病毒(HSV)疾病的发生和发展可能做出的贡献
Lisa N Akhtar,Moriah L Szpara
Lisa N Akhtar
Purpose of review: Neonatal infection by herpes simplex virus (HSV) 1 or 2 presents a devastating burden to new parents, due to the unpredictability of severe clinical outcomes, as well as the potential for lifelong react...
Maria I Giraldo,Adam Hage,Sarah van Tol et al.
Maria I Giraldo et al.
Purpose of review: Tripartite motif (TRIM) proteins are a large group of E3 ubiquitin ligases involved in different cellular functions. Of special interest are their roles in innate immunity, inflammation, and virus repli...
Picornavirus Cellular Remodeling: Doubling Down in Response to Viral-Induced Inflammation [0.03%]
皮病毒对细胞重塑的反应：针对病毒引起的炎症加倍应对
Alexis Bouin,Bert L Semler
Alexis Bouin
Purpose of review: To highlight recent findings on how picornavirus infections of the airways and cardiac tissues impact cellular inflammation and remodeling events. ...
Depriving Iron Supply to the Virus Represents a Promising Adjuvant Therapeutic Against Viral Survival [0.03%]
剥夺病毒铁供应代表了抑制病毒生存的有前景的辅助治疗方案
Wei Liu,Shuping Zhang,Sergei Nekhai et al.
Wei Liu et al.
Purpose of the review: The ongoing outbreak of novel coronavirus pneumonia (COVID-19) caused by the 2019 novel coronavirus (SARS-CoV-2) in China is lifting widespread concerns. Thus, therapeutic options are urgently neede...
Ilan S Schwartz,Chris Kenyon,George R Thompson rd
Ilan S Schwartz
Infections with geographically constrained dimorphic fungi cause the endemic mycoses, which include blastomycosis, coccidioidomycosis, emmonsiosis, histoplasmosis, paracoccidioidomycosis, sporotrichosis, and penicilliosis. In the last 5 yea...
Molecular Pathogenesis of Middle East Respiratory Syndrome (MERS) Coronavirus [0.03%]
中东呼吸综合征冠状病毒的分子发病机制
Arinjay Banerjee,Kaushal Baid,Karen Mossman
Arinjay Banerjee
Purpose of review: Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 and is listed in the World Health Organization's blueprint of priority diseases that need immediate research. Camels are reservoir...
Claudia Bachofen
Claudia Bachofen
Purpose of review: The purpose of this review is to provide an update on recent literature and findings concerning selected foodborne viruses. Two groups of viruses were selected: (a) the most important viruses contaminat...
Attenuation of Viruses by Large-Scale Recoding of their Genomes: the Selection Is Always Biased [0.03%]
大规模基因组重编码削弱病毒效果：选择总是有偏差的
Nikolaus Osterrieder,Dusan Kunec
Nikolaus Osterrieder
Purpose of review: This review summarizes the current understanding of virus attenuation by large-scale recoding of viral genomes and discusses what would ultimately be necessary for construction of better and safer live ...
Allaura S Cone,Sara B York,David G Meckes Jr
Allaura S Cone
Purpose of review: Epstein-Barr virus (EBV) is a known determinant for numerous malignancies and may contribute to autoimmune diseases. The underlining mechanisms behind EBV pathologies is not completely understood. Recen...
The complexity of interactions between female sex hormones and Chlamydia trachomatis infections [0.03%]
女性性激素与沙眼衣原体感染之间相互作用的复杂性
Amy Berry,Jennifer V Hall
Amy Berry
Purpose of review: This review focuses specifically on the mechanisms by which female sex hormones, estrogen and progesterone, affect Chlamydia trachomatis infections in vivo and in vitro. ...