Derek J Pinto,Sumiti Vinayak
Derek J Pinto
Purpose of review: Cryptosporidium spp. (C. hominis and C. parvum) are a major cause of diarrhea-associated morbidity and mortality in young children globally. While C. hominis only infects humans, C. parvum is a zoonotic...
Anti-viral immunity in the tumor microenvironment: implications for the rational design of herpes simplex virus type 1 oncolytic virotherapy [0.03%]
肿瘤微环境中抗病毒免疫与溶瘤病毒治疗：HSV-1溶瘤病毒疗法的理性设计之考虑因素
Paul J F Rider,Ifeanyi K Uche,Larissa Sweeny et al.
Paul J F Rider et al.
Purpose of review: The design of novel herpes simplex type I (HSV-1)-derived oncolytic virotherapies is a balancing act between safety, immunogenicity and replicative potential. We have undertaken this review to better un...
Candida auris infection and biofilm formation: going beyond the surface [0.03%]
芽生菌感染及生物被膜形成：表面之下的问题
Mark V Horton,Jeniel E Nett
Mark V Horton
Purpose of review: Emergent fungal pathogen C. auris is spreading in hospitals throughout the world and mortality rates for patients with invasive disease approach 60%. This species exhibits a heightened capacity to colon...
Darin J Weed,Blossom Damania
Darin J Weed
Purpose of this review: Human gammaherpesviruses have complex lifecycles that drive their pathogenesis. KSHV and EBV are the etiological agents of multiple cancers worldwide. There is no FDA-approved vaccine for either KS...
Reovirus: Friend and Foe [0.03%]
轮状病毒：敌与友
Michael R Eledge,Marcelle Dina Zita,Karl W Boehme
Michael R Eledge
Purpose of review: Mammalian orthoreovirus (reovirus) is a powerful tool for studying viral replication and pathogenesis. Most reovirus infections are subclinical, however recent work has catapulted reovirus into the clin...
Qingxue Li,Jeffrey I Cohen
Qingxue Li
Purpose: While most adults are infected Epstein-Barr virus (EBV), 3-5% remain uninfected. The human leukocyte antigen (HLA) complex, which controls many pathogens, may influence infection and disease associated with EBV. ...
Listeria monocytogenes cancer vaccines: bridging innate and adaptive immunity [0.03%]
单核细胞李斯特氏菌癌症疫苗：连接先天和适应性免疫
Zachary T Morrow,Zachary M Powers,John-Demian Sauer
Zachary T Morrow
Purpose of the review: Immunotherapy has emerged as a promising cancer treatment, however success in only select clinical indications underscores the need for novel approaches. Recently Listeria monocytogenes-based vaccin...
Biology and function of exo-polysaccharides from human fungal pathogens [0.03%]
人类真菌病原体中exo-多糖的生物和功能
Krystal Y Chung,Jessica C S Brown
Krystal Y Chung
Purpose of review: Environmental fungi such as Cryptococcus neoformans and Aspergillus fumigatus must survive many different and changing environments as they transition from their environmental niches to human lungs and ...
Ibtissam Bentaleb,Kawther Ben Abdelghani,Samira Rostom et al.
Ibtissam Bentaleb et al.
Purpose of review: The aim of this paper is to provide an overview about reactive arthritis, with an update regarding pathophysiology and therapeutic approach of the disease, outlining the clinical features and diagnostic...
Océane Sorel,Ilhem Messaoudi
Océane Sorel
Purpose of review: Varicella zoster virus (VZV) is a highly contagious, neurotropic alpha herpes virus that causes varicella (chickenpox). VZV establishes lifelong latency in the sensory ganglia from which it can reactiva...